[go: up one dir, main page]

BR9910414A - Isolated protein, isolated nucleic acid, vector for the expression of a psidium guajava 13-hydroperoxide lyase, cell containing an exogenous nucleic acid, and processes for cleaving a 13-hydroperoxide of linoleic acid or an alpha-linolenic acid in a c6 aldehyde and a c12 oxocarboxylic acid, to prepare n-hexanal, 3- (z) -hexen-1-al, 2- (e) -hexen-1-al or its corresponding alcohols, and to express a recombinant protein - Google Patents

Isolated protein, isolated nucleic acid, vector for the expression of a psidium guajava 13-hydroperoxide lyase, cell containing an exogenous nucleic acid, and processes for cleaving a 13-hydroperoxide of linoleic acid or an alpha-linolenic acid in a c6 aldehyde and a c12 oxocarboxylic acid, to prepare n-hexanal, 3- (z) -hexen-1-al, 2- (e) -hexen-1-al or its corresponding alcohols, and to express a recombinant protein

Info

Publication number
BR9910414A
BR9910414A BR9910414-8A BR9910414A BR9910414A BR 9910414 A BR9910414 A BR 9910414A BR 9910414 A BR9910414 A BR 9910414A BR 9910414 A BR9910414 A BR 9910414A
Authority
BR
Brazil
Prior art keywords
acid
hexen
hydroperoxide
nucleic acid
protein
Prior art date
Application number
BR9910414-8A
Other languages
Portuguese (pt)
Other versions
BR9910414B1 (en
Inventor
Ian Michael Whitehead
Alan John Slusarenko
Urs Wospi
Duncan James Horatio Gaskin
Alan Richard Brash
Nathalie Tijet
Original Assignee
Firmenich & Cie
Univ Vanderbilt
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich & Cie, Univ Vanderbilt, Univ Zuerich filed Critical Firmenich & Cie
Publication of BR9910414A publication Critical patent/BR9910414A/en
Publication of BR9910414B1 publication Critical patent/BR9910414B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"PROTEìNA ISOLADA, áCIDO NUCLEICO ISOLADO, VETOR PARA A EXPRESSãO DE UMA 13-HIDROPERóXIDO LIASE DE PSIDIUM GUAJAVA, CéLULA CONTENDO UM áCIDO NUCLEICO EXóGENO, E, PROCESSOS PARA CLIVAR UM 13-HIDROPERóXIDO DE áCIDO LINOLEICO OU DE UM ALFA-LINOLêNICO EM UM ALDEìDO C6 E UM áCIDO OXOCARBOXìLICO C12, PARA PREPARAR N-HEXANAL, 3-(Z)-HEXEN-1-AL, 2-(E)-HEXEN-1-AL OU SEUS áLCOOIS CORRESPONDENTES, E PARA EXPRESSAR UMA PROTEìNA RECOMBINANTE". A presente invenção diz respeito a um ácido graxo da proteína 13-hidroperóxido liase de goiaba (Psidium guajava) e ao gene que codifica a protéina. Sistemas de expressão para a 13-hidroperóxido liase recombinante da goiaba e processos de usar 13-hidroperóxido liase recombinante da goiaba para a produção de caráteres verdes são fornecidos."ISOLATED PROTEIN, ISOLATED NUCLEIC ACID, VECTOR FOR THE EXPRESSION OF A 13-HYDROPEROXIDE LIASE FROM PSIDIUM GUAJAVA, CELL CONTAINING AN EXOGENOUS NUCLEIC ACID, AND PROCESSES TO CLAIM A 13-HYDROPEROXIC ALUMIN ALUMINUM LINEN C6 AND A C12 OXOCARBOXYLIC ACID, TO PREPARE N-HEXANAL, 3- (Z) -HEXEN-1-AL, 2- (E) -HEXEN-1-AL OR ITS CORRESPONDING ALCOHOLS, AND TO EXPRESS A RECOMBINANT PROTEIN ". The present invention concerns a fatty acid of guava 13-hydroperoxide lyase (Psidium guajava) and the gene encoding the protein. Expression systems for the recombinant guava 13-hydroperoxide lyase and processes for using recombinant guava 13-hydroperoxide lyase for the production of green characters are provided.

BRPI9910414-8A 1998-05-13 1999-05-05 transgenic escherichia coli or yeast cell, and process for cleaving a 13-hydroperoxide of linoleic or alpha-linolenic acid into a c6 aldehyde and a c12 oxocarboxylic acid. BR9910414B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/078,173 US6200794B1 (en) 1998-05-13 1998-05-13 Guava (Psidium guajava) 13-hydroperoxide lyase and uses thereof
PCT/IB1999/000807 WO1999058648A2 (en) 1998-05-13 1999-05-05 Guava (psidium guajava) 13-hydroperoxide lyase and uses thereof

Publications (2)

Publication Number Publication Date
BR9910414A true BR9910414A (en) 2001-09-04
BR9910414B1 BR9910414B1 (en) 2012-09-18

Family

ID=22142395

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9910414-8A BR9910414B1 (en) 1998-05-13 1999-05-05 transgenic escherichia coli or yeast cell, and process for cleaving a 13-hydroperoxide of linoleic or alpha-linolenic acid into a c6 aldehyde and a c12 oxocarboxylic acid.

Country Status (6)

Country Link
US (1) US6200794B1 (en)
EP (1) EP1080205B1 (en)
BR (1) BR9910414B1 (en)
DE (1) DE69938343T2 (en)
ES (1) ES2301238T3 (en)
WO (1) WO1999058648A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000022145A2 (en) * 1998-10-13 2000-04-20 Pioneer Hi-Bred International, Inc. A hydroperoxide lyase gene from maize and methods of use
US6271018B1 (en) * 2000-03-29 2001-08-07 Vanderbilt University Muskmelon (Cucumis melo) hydroperoxide lyase and uses thereof
DE10028639C2 (en) * 2000-06-09 2003-11-06 Ipk Inst Fuer Pflanzengenetik Process for the preparation of C9 aldehydes, C9 alcohols and their esters
US20040010822A1 (en) * 2002-05-10 2004-01-15 Mcgonigle Brian Hydroperoxyde lyases
PL2167658T3 (en) * 2007-06-28 2013-04-30 Firmenich & Cie Modified 13-hydroperoxide lyases and uses thereof
CN120005901A (en) * 2025-01-21 2025-05-16 浙江大学 A tomato SlMET1L gene and its application in regulating fruit ripening and preservation quality

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69320302T2 (en) 1992-05-26 1999-01-28 Dean, Christopher, Grand-Lancy Enzymatic process for the preparation of n-hexanal, 3- (Z) -hexen-1-al, 2- (E) -hexen-1-al, or corresponding alcohols using a soybean lipoxygenase and a guava lyase
EP0801133B1 (en) 1996-04-15 2004-09-08 Givaudan SA Hydroperoxide lyases
CA2301856A1 (en) 1998-06-26 2000-01-06 Calgene Llc Fatty acid hydroperoxide lyase nucleic acid sequences

Also Published As

Publication number Publication date
DE69938343D1 (en) 2008-04-24
US6200794B1 (en) 2001-03-13
ES2301238T3 (en) 2008-06-16
EP1080205B1 (en) 2008-03-12
WO1999058648A2 (en) 1999-11-18
DE69938343T2 (en) 2009-03-26
EP1080205A2 (en) 2001-03-07
WO1999058648A3 (en) 2000-02-24
BR9910414B1 (en) 2012-09-18

Similar Documents

Publication Publication Date Title
CL2021002740A1 (en) A prevotella and francisella crispr protein 1 (cpf1) isolated from acidaminococcus sp. bv3l6(ascpf1); fusion protein comprising it; nucleic acid; vector; methods for altering the genome of a cell or a dsna molecule in vitro using said proteins (divisional de sol. 201903004)
NO20101157L (en) FAD4, FAD5, FAD5-2 and FAD6, new fatty acid desaturase family members and uses thereof
WO2002008388A3 (en) Stem cell-like cells
AU2220800A (en) Compositions and methods for packaging of alphavirus vectors
BR0015631A (en) Plant, polynucleotide, vector, cell, composition, polypeptide, methods for producing a plant and for identifying a factor that is modulated by, or interacts with, a polypeptide encoded by a polynucleotide, a molecule that modulates the activity or expression of a polynucleotide or polypeptide of interest, and a sequence similar or homologous to one or more polynucleotides, and, integrated system, computerized or legible in computer
IL164803A0 (en) Means and methods for the production of adenovirusvectors
BR9811865A (en) Isolation of a new senescence factor gene, p23
AR004668A1 (en) A PURIFIED ISOLATED NUCLEIC ACID, A RECOMBINING VECTOR OF EXPRESSION THAT UNDERSTANDS IT, A CELL THAT INCLUDES SUCH A VECTOR, A METHOD FOR THE PRODUCTION OF A H.PYLORI POLYPEPTIDE, A COMPOSITION OF A VACCINE, A PREPARED COMPOSITION PURIFIED BY H.
BR0116033A (en) Isothermal amplification of nucleic acids on a solid support
MX428A (en) REGULATORY REGION FOR EXPRESSION OF HETEROLOGY GENE IN YEAST.
ES8800726A1 (en) METHOD FOR THE MANUFACTURE OF A TEST FOR THE DETECTION OF D.N.A. OF A LYMPHADENOCYTE VIRUS.
BR9813608A (en) Isolated polypeptide, isolated and mutant nucleic acid sequences, nucleic acid construction, recombinant expression vector, recombinant host cell, processes for producing a mutant nucleic acid sequence, for producing a polypeptide, for producing a mutant of an originating cell and for produce a protein, and, mutant cell
BR9910414A (en) Isolated protein, isolated nucleic acid, vector for the expression of a psidium guajava 13-hydroperoxide lyase, cell containing an exogenous nucleic acid, and processes for cleaving a 13-hydroperoxide of linoleic acid or an alpha-linolenic acid in a c6 aldehyde and a c12 oxocarboxylic acid, to prepare n-hexanal, 3- (z) -hexen-1-al, 2- (e) -hexen-1-al or its corresponding alcohols, and to express a recombinant protein
DE69933550D1 (en) MODIFIED ADENOVIRES CONTAINING A FIBER SPARE PROTEIN
BR0016867A (en) Insulin analog precursor, polynucleotide sequence, expression vector, host cell, and processes for making an insulin analog precursor and for making an insulin analog
ATE319848T1 (en) PRODUCTION OF POLYKETIDES
BR0103240A (en) Process for the production of a target fermentation product
ZA202501953B (en) Masking polypeptide, activatable novel prodrugs and methods of use thereof
DK0953644T3 (en) Systems for mass production of proteins or peptides by microorganisms of the genus Humicola
BR9811850A (en) Recombinant expression of insulin c peptide
BRPI0414670A (en) method for preparing a cell, cell, methods for providing a cell and for generating a batch of recombinant adenovirus, recombinant molecule, assembly of at least two nucleic acid molecules, and packaging system
BR0316510A (en) Expression vector, process for the preparation of heterologous gene products and selection process for high yield recombinant cells
ATE203770T1 (en) DNA COMPOSITION AND MODIFIED YEAST
Lithgow et al. Identification of a GTP-binding protein in the contact sites between inner and outer mitochondrial membranes
DE59913079D1 (en) RECOMBINANT MISTLE LEMONS

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DE C12N 9/00.

Ipc: C12N 9/88 (2009.01), C12P 7/42 (2009.01)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/09/2012, OBSERVADAS AS CONDICOES LEGAIS.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 18/09/2022