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BR9909388A - Use of at least one leishmania cysteine proteinase, vaccine, protein lpa. infantum, genes cpa and cpb of l. infantum, cpa or cpb, and, use of the cpa and / or cpb proteins or the nucleic acid sequences of the cpa and / or cpb - Google Patents

Use of at least one leishmania cysteine proteinase, vaccine, protein lpa. infantum, genes cpa and cpb of l. infantum, cpa or cpb, and, use of the cpa and / or cpb proteins or the nucleic acid sequences of the cpa and / or cpb

Info

Publication number
BR9909388A
BR9909388A BR9909388-0A BR9909388A BR9909388A BR 9909388 A BR9909388 A BR 9909388A BR 9909388 A BR9909388 A BR 9909388A BR 9909388 A BR9909388 A BR 9909388A
Authority
BR
Brazil
Prior art keywords
cpa
cpb
infantum
vaccine
proteins
Prior art date
Application number
BR9909388-0A
Other languages
Portuguese (pt)
Inventor
Jeremy Charles Mottram
Graham Herbert Coombs
Original Assignee
Univ Glasgow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Glasgow filed Critical Univ Glasgow
Publication of BR9909388A publication Critical patent/BR9909388A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/008—Leishmania antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

"USO DE PELO MENOS UMA LEISHMANIA CISTEìNA PROTEINASE, VACINA, PROTEìNA CPA DO L. INFANTUM, GENES CPA E CPB DO L. INFANTUM, CPA OU CPB, E, USO DAS PROTEìNAS CPA E/OU CPB OU DAS SEQUêNCIAS DE áCIDO NUCLéICO DO CPA E/OU CPB" A presente invenção diz respeito a uma vacina contra o Leishmania, mais particularmente uma vacina contra o Leishmania que compreenda cisteína proteinase(s) ativa(s) ou inativa(s), particularmente na forma recombinante, para o uso na imunização de mamíferos, tais como cães e/ou seres humanos."USE OF AT LEAST ONE CYSTAL LEISHMANIA PROTEINASE, VACCINE, L. INFANTUM CPA PROTEIN, L. INFANTUM CPA AND CPB GENES, CPA OR CPB, AND USE OF THE CPA AND / OR CPB PROTEINS OR THE CPA NUCLEIC ACID SEQUENCES AND / OR CPB "The present invention relates to a Leishmania vaccine, more particularly a Leishmania vaccine comprising active or inactive cysteine proteinase (s), particularly in recombinant form, for use in immunization of mammals, such as dogs and / or humans.

BR9909388-0A 1998-04-03 1999-04-06 Use of at least one leishmania cysteine proteinase, vaccine, protein lpa. infantum, genes cpa and cpb of l. infantum, cpa or cpb, and, use of the cpa and / or cpb proteins or the nucleic acid sequences of the cpa and / or cpb BR9909388A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9807293.7A GB9807293D0 (en) 1998-04-03 1998-04-03 Leishmania cysteine proteinases
PCT/GB1999/000889 WO1999051264A2 (en) 1998-04-03 1999-04-06 Leishmania cysteine proteinases

Publications (1)

Publication Number Publication Date
BR9909388A true BR9909388A (en) 2000-12-05

Family

ID=10829885

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9909388-0A BR9909388A (en) 1998-04-03 1999-04-06 Use of at least one leishmania cysteine proteinase, vaccine, protein lpa. infantum, genes cpa and cpb of l. infantum, cpa or cpb, and, use of the cpa and / or cpb proteins or the nucleic acid sequences of the cpa and / or cpb

Country Status (6)

Country Link
EP (1) EP1067961A2 (en)
AP (1) AP2000001945A0 (en)
BR (1) BR9909388A (en)
GB (1) GB9807293D0 (en)
IL (1) IL138639A0 (en)
WO (1) WO1999051264A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9706930D0 (en) 1997-04-04 1997-05-21 Univ Glasgow Leishmania vaccine
GB0008903D0 (en) * 2000-04-12 2000-05-31 Univ Glasgow Stage-specific sequences
DE60131423T2 (en) * 2000-09-08 2009-03-19 Prozymex A/S RAT SPECIFIC CATHEPSIN, DIPEPTIDYL PEPTIDASE I (DPPI): CRYSTAL STRUCTURE, INGREDIENTS AND ITS APPLICATIONS
US7736875B2 (en) 2000-09-08 2010-06-15 Prozymex A/S Dipeptidyl peptidase I crystal structure and its uses
BRPI0915371A2 (en) 2008-07-04 2016-10-18 Inst Rech Developpement Ird a method for evaluation of conserved secreted proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9706930D0 (en) * 1997-04-04 1997-05-21 Univ Glasgow Leishmania vaccine

Also Published As

Publication number Publication date
WO1999051264A2 (en) 1999-10-14
IL138639A0 (en) 2001-10-31
WO1999051264A3 (en) 1999-12-09
GB9807293D0 (en) 1998-06-03
AP2000001945A0 (en) 2000-12-31
EP1067961A2 (en) 2001-01-17

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DEPACHO 8.6 DA RPI 1994 DE 24/03/2009