BR9906833A - Processes and compositions to treat diagnosing insulin-related disorders - Google Patents
Processes and compositions to treat diagnosing insulin-related disordersInfo
- Publication number
- BR9906833A BR9906833A BR9906833-8A BR9906833A BR9906833A BR 9906833 A BR9906833 A BR 9906833A BR 9906833 A BR9906833 A BR 9906833A BR 9906833 A BR9906833 A BR 9906833A
- Authority
- BR
- Brazil
- Prior art keywords
- processes
- treat
- compositions
- insulin
- related disorders
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 102000004877 Insulin Human genes 0.000 title abstract 3
- 108090001061 Insulin Proteins 0.000 title abstract 3
- 229940125396 insulin Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 238000009825 accumulation Methods 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 230000017854 proteolysis Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Abstract
"PROCESSOS E COMPOSIçõES PARA TRATAR EDIAGNOSTICAR DISTúRBIOS RELACIONADOS à INSULINA".A presente invenção refere-se aos processos e composições paratratar ou reduzir sintomas de distúrbios de deficiência absoluta ourelativa à insulina, resistência severa à insulina, de acúmulo ouexcesso de síntese de lipídeos, ou de catabolismo ou degradaçãode proteína. A invenção também inclui processos para detectar eavaliar tratamentos de tais distúrbios."PROCESSES AND COMPOSITIONS TO TREAT EDIAGNOSTICATE INSULIN-RELATED DISORDERS" .The present invention relates to processes and compositions to treat or reduce symptoms of absolute insulin deficiency disorders, severe resistance to insulin, accumulation or excess lipid synthesis, or catabolism or protein degradation. The invention also includes processes for detecting and evaluating treatments for such disorders.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7082198P | 1998-01-08 | 1998-01-08 | |
| PCT/US1999/000471 WO1999035169A2 (en) | 1998-01-08 | 1999-01-08 | Methods and compositions for treating and diagnosing insulin related disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9906833A true BR9906833A (en) | 2001-11-27 |
Family
ID=22097585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9906833-8A BR9906833A (en) | 1998-01-08 | 1999-01-08 | Processes and compositions to treat diagnosing insulin-related disorders |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1045860A2 (en) |
| JP (1) | JP2002500234A (en) |
| CN (1) | CN1292798A (en) |
| AU (1) | AU2313899A (en) |
| BR (1) | BR9906833A (en) |
| CA (1) | CA2317674A1 (en) |
| WO (1) | WO1999035169A2 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6465714B2 (en) | 1999-11-05 | 2002-10-15 | Arexis Ab | Congenic animal models of non-insulin dependent diabetes mellitus |
| US20090023630A1 (en) * | 2005-01-31 | 2009-01-22 | Jan Wouter Drijfhout | Methods and Means for Use in Diagnostics and Treatment of Diabetes |
| JP2012507021A (en) * | 2008-10-31 | 2012-03-22 | ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | Methods and assays for classifying foods and / or beverages and / or diets and / or nutrition plans and / or drugs for effects on the cardiovascular system |
| EP2391377A2 (en) | 2009-02-02 | 2011-12-07 | Ramot at Tel-Aviv University Ltd. | Peptides, pharmaceutical compositions comprising same and uses thereof |
| US8901074B2 (en) | 2010-08-04 | 2014-12-02 | Ramot At Tel-Aviv University | Methods of treating autoimmune diseases of the central nervous system (CNS) and neurodegenerative diseases |
| CN104961706B (en) * | 2015-07-06 | 2017-03-01 | 成都知普莱生物医药科技有限公司 | A kind of method of insulin synthesis degraded enzyme inhibitor ML345 |
| CN115477686B (en) * | 2022-09-22 | 2024-01-30 | 北海黑珍珠海洋生物科技有限公司 | Pearl shell active peptide with whitening effect and application thereof |
| CN119322179B (en) * | 2024-09-03 | 2025-11-11 | 中日友好医院(中日友好临床医学研究所) | Application of biomarker in predicting diabetes strengthening treatment effect and kit |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5891435A (en) * | 1993-04-16 | 1999-04-06 | Research Corporation Technologies, Inc. | Methods and compositions for delaying or preventing the onset of autoimmune disease |
| AUPM411994A0 (en) * | 1994-02-25 | 1994-03-24 | Deakin Research Limited | Epitopes |
| US5594100A (en) * | 1995-02-22 | 1997-01-14 | Regents Of The University Of Colorado | Epitope for prevention of type I diabetes |
-
1999
- 1999-01-08 EP EP99903019A patent/EP1045860A2/en not_active Withdrawn
- 1999-01-08 WO PCT/US1999/000471 patent/WO1999035169A2/en not_active Ceased
- 1999-01-08 CN CN 99803812 patent/CN1292798A/en active Pending
- 1999-01-08 AU AU23138/99A patent/AU2313899A/en not_active Abandoned
- 1999-01-08 BR BR9906833-8A patent/BR9906833A/en not_active IP Right Cessation
- 1999-01-08 JP JP2000527564A patent/JP2002500234A/en active Pending
- 1999-01-08 CA CA002317674A patent/CA2317674A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2317674A1 (en) | 1999-07-15 |
| JP2002500234A (en) | 2002-01-08 |
| WO1999035169A9 (en) | 1999-11-11 |
| EP1045860A2 (en) | 2000-10-25 |
| CN1292798A (en) | 2001-04-25 |
| AU2313899A (en) | 1999-07-26 |
| WO1999035169A3 (en) | 1999-10-07 |
| WO1999035169A2 (en) | 1999-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 5A,6A,7A E 8A ANUIDADES |
|
| B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007. |