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BR9816013A - Proteìna de ligação de interleucina-18 - Google Patents

Proteìna de ligação de interleucina-18

Info

Publication number
BR9816013A
BR9816013A BR9816013-3A BR9816013A BR9816013A BR 9816013 A BR9816013 A BR 9816013A BR 9816013 A BR9816013 A BR 9816013A BR 9816013 A BR9816013 A BR 9816013A
Authority
BR
Brazil
Prior art keywords
protein
substance
binding
binding protein
interleukin
Prior art date
Application number
BR9816013-3A
Other languages
English (en)
Inventor
Kakuji Torigoe
Madoka Taniai
Masashi Kurimoto
Original Assignee
Hayashibara Biochem Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hayashibara Biochem Lab filed Critical Hayashibara Biochem Lab
Publication of BR9816013A publication Critical patent/BR9816013A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"PROTEìNA DE LIGAçãO DE INTERLEUCINA-18". Os objetivos desta invenção são prover uma substância que suprime as atividades fisiológicas de IL-18 através da ligação a IL-18, usos da substância, e um DNA que codifica a substância; esta invenção alcança estes objetivos por prover uma proteína de ligação de IL-18 compreendendo uma seq³ência de aminoácidos específica, um DNA que codifica esta proteína, e um supressor de IL-18 bem como agente para doenças suscetíveis contendo como um ingrediente eficaz esta proteína de ligação de IL-18.
BR9816013-3A 1998-09-01 1998-11-18 Proteìna de ligação de interleucina-18 BR9816013A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP24758898 1998-09-01
PCT/JP1998/005186 WO2000012555A1 (en) 1998-09-01 1998-11-18 Interleukin 18-binding protein
JP32791498 1998-11-18

Publications (1)

Publication Number Publication Date
BR9816013A true BR9816013A (pt) 2003-01-21

Family

ID=26538338

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9816013-3A BR9816013A (pt) 1998-09-01 1998-11-18 Proteìna de ligação de interleucina-18

Country Status (6)

Country Link
US (1) US20050191303A1 (pt)
EP (1) EP1110969A4 (pt)
KR (1) KR100537558B1 (pt)
BR (1) BR9816013A (pt)
CA (1) CA2340579A1 (pt)
WO (1) WO2000012555A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220717B2 (en) 1997-08-14 2007-05-22 Yeda Research And Development Company Ltd. Interleukin-18 binding proteins, their preparation and use
US7704944B2 (en) 1997-08-14 2010-04-27 Yeda Research And Development Company Ltd. Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis
IL121860A0 (en) 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
CA2399148A1 (en) 2000-02-10 2001-08-16 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
DK1257292T3 (da) * 2000-02-21 2011-07-18 Merck Serono Sa Anvendelse af IL-18-inhibitorer
KR100798545B1 (ko) * 2000-05-05 2008-01-28 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. 죽상경화증의 치료 또는 예방을 위한 ｉｌ-18 저해물질의용도
US6818444B2 (en) 2000-08-04 2004-11-16 Heska Corporation Canine and feline proteins, nucleic acid molecules and uses thereof
AU1174402A (en) 2000-10-11 2002-04-22 Viron Therapeutics Inc Nucleic acid molecules and polypeptides for immune modulation
EP1834960A3 (en) * 2000-12-04 2007-10-03 Viron Therapeutics, Inc. Immunomodulatory protein derived from the yaba monkey tumor virus
DE60128950T2 (de) * 2000-12-04 2008-02-28 Viron Therapeutics, Inc., London Immunmodulatorisches Protein abgeleitet vom Yaba-Affentumor-Virus
US7718368B2 (en) 2000-12-04 2010-05-18 Viron Therapeutics Inc. Immunomodulatory protein and useful embodiments thereof
ATE380558T1 (de) * 2001-01-29 2007-12-15 Serono Lab Verwendung von il-18 hemmern zur behandlung und/oder prävention von herzkrankheiten
ES2706902T3 (es) 2001-06-26 2019-04-01 Amgen Inc Anticuerpos para OPGL
UA78516C2 (en) * 2001-08-10 2007-04-10 Applied Research Systems Use of inhibitors of il-18 for treatment and/or prevention of hypersensitivity disorders, and in particular of delayed-type hypersensitivity
RS51755B (sr) * 2002-03-22 2011-12-31 Laboratoires Serono Sa. Korišćenje inhibitora il-18 za lečenje i/ili prevenciju perifernih vaskularnih bolesti
AU2003299971A1 (en) 2002-12-30 2004-07-29 Amgen Inc. Combination therapy with co-stimulatory factors
US20080076708A1 (en) * 2003-05-13 2008-03-27 Valter Altarocca Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
PT1689777E (pt) * 2003-11-05 2007-05-31 Ares Trading Sa Processo para a purificação da proteína de ligação a il-18
US20050100965A1 (en) 2003-11-12 2005-05-12 Tariq Ghayur IL-18 binding proteins
NZ549040A (en) 2004-02-17 2009-07-31 Schering Corp Use for interleukin-33 (IL33) and the IL-33 receptor complex
EP1761552B1 (en) * 2004-06-29 2008-09-17 Ares Trading S.A. Process for the purification of il-18 binding protein
US7141382B1 (en) 2004-10-12 2006-11-28 Parikh Chirag R Methods for detection of IL-18 as an early marker for diagnosis of acute renal failure and predictor of mortality
DK1888100T3 (da) * 2005-06-03 2012-01-23 Merck Serono Sa Anvendelse af IL-18BP-isoformer til behandling og/eller forebyggelse af neurologiske inflammatoriske sygdomme
WO2007145618A1 (en) * 2006-06-12 2007-12-21 Therakine Limited Topical treatment for diseases of eye surface
CL2008002153A1 (es) * 2007-07-24 2009-06-05 Amgen Inc Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
SG11201706879UA (en) * 2015-03-05 2017-09-28 Ab2 Bio Sa Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087116A (en) * 1997-03-12 2000-07-11 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18 (IL-18) receptor polypeptides and their uses
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use

Also Published As

Publication number Publication date
KR20010074925A (ko) 2001-08-09
EP1110969A1 (en) 2001-06-27
KR100537558B1 (ko) 2005-12-19
CA2340579A1 (en) 2000-03-09
WO2000012555A1 (en) 2000-03-09
US20050191303A1 (en) 2005-09-01
EP1110969A4 (en) 2002-01-09

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Legal Events

Date Code Title Description
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 37, SUGIRO O INDEFERIMENTO DO PRESENTE PEDIDO, TENDO POR BASE O ART. 10 (IX) DA LPI 9279 DE 14/05/96.