[go: up one dir, main page]

BR9815780A - Antibióticos na forma de dosagem seca para otratamento de úlceras superficiais da mucosaoral - Google Patents

Antibióticos na forma de dosagem seca para otratamento de úlceras superficiais da mucosaoral

Info

Publication number
BR9815780A
BR9815780A BR9815780-9A BR9815780A BR9815780A BR 9815780 A BR9815780 A BR 9815780A BR 9815780 A BR9815780 A BR 9815780A BR 9815780 A BR9815780 A BR 9815780A
Authority
BR
Brazil
Prior art keywords
antibiotics
troche
powder
treatment
dosage form
Prior art date
Application number
BR9815780-9A
Other languages
English (en)
Inventor
Kee Hung Hau
Original Assignee
Kee Hung Hau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kee Hung Hau filed Critical Kee Hung Hau
Publication of BR9815780A publication Critical patent/BR9815780A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/245—Bismuth; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: "ANTIBIóTICOS NA FORMA DEDOSAGEM SECA PARA O TRATAMENTO DE úLCERASSUPERFICIAIS DA MUCOSA ORAL". A invenção fornece ummedicamento para tratamento tópico de úlceras aftosas na mucosaoral e processo de utilização. O medicamento compreende umtrocisco ou pó que compreende uma dosagem seca de um ou maisantibióticos e, preferencialmente, um ou mais compostos de metalpolivalente. O trocisco ou pó é diretamente aplicado na úlceraaftosa e se dissolve na saliva, dentro de aproximadamente 5 atéaproximadamente 15 minutos, distribuindo desta forma diretamenteuma dosagem supraterapêutica do antibiótico no tecido oralulcerado. Ainda, em uma modalidade preferida o trocisco/pódistribui diretamente uma concentração terapeuticamente alta deum composto de metal polivalente em suspensão para a úlceraaftosa, formando desta forma uma barreira protetora sobre o tecidooral ulcerado.
BR9815780-9A 1998-02-20 1998-04-30 Antibióticos na forma de dosagem seca para otratamento de úlceras superficiais da mucosaoral BR9815780A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/026,901 US5981499A (en) 1998-02-20 1998-02-20 Lesion-directed antibiotics in dry dosage forms for the treatment of shallow ulcers of the oral mucosa
PCT/US1998/008661 WO1999042083A1 (en) 1998-02-20 1998-04-30 Antibiotics in dry dosage forms for the treatment of shallow ulcers of the oral mucosa

Publications (1)

Publication Number Publication Date
BR9815780A true BR9815780A (pt) 2001-11-20

Family

ID=21834443

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9815780-9A BR9815780A (pt) 1998-02-20 1998-04-30 Antibióticos na forma de dosagem seca para otratamento de úlceras superficiais da mucosaoral

Country Status (11)

Country Link
US (1) US5981499A (pt)
EP (1) EP1056442B1 (pt)
JP (1) JP2002503684A (pt)
CN (1) CN1181821C (pt)
AT (1) ATE245967T1 (pt)
AU (1) AU762585B2 (pt)
BR (1) BR9815780A (pt)
CA (1) CA2320731C (pt)
DE (1) DE69816870T2 (pt)
RU (1) RU2211022C2 (pt)
WO (1) WO1999042083A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458777B1 (en) * 1998-03-13 2002-10-01 Mucosal Therapeutics Llc Methods and compositions for treating and preventing mucositis
US6248718B1 (en) 1999-08-18 2001-06-19 Atlantic Biomed Corporation Lesion-directed dry dosage forms of antibacterial agents for the treatment of acute mucosal infections of the oral cavity
US6946118B1 (en) * 1999-09-14 2005-09-20 Orapharma, Inc. Formulations for treating or preventing mucositis
EP1212050B1 (en) * 1999-09-14 2006-12-06 Mucosal Therapeutics LLC Formulations containing tetracyclines for treating or preventing mucositis
EP1829546A1 (en) * 1999-09-14 2007-09-05 Mucosal Therapeutics LLC Formulations containing tetracyclines for treating or preventing mucositis
US6821953B1 (en) * 1999-12-16 2004-11-23 University Of Southern California Methods for treating and preventing damage to mucosal tissue
AU2001274420A1 (en) * 2000-07-11 2002-01-21 Micio Pharma Chemical Ag Anhydrous pharmaceutical composition of vancomycin for topical use
IT1320772B1 (it) * 2000-11-02 2003-12-10 Proge Farm Srl Composizione farmaceutica a base di agenti attivi contro la candidaper il trattamento di disturbi della mucosa orale e intestinale
CA2443944A1 (en) * 2001-04-17 2002-10-31 Tanabe Seiyaku Co., Ltd. Agent for prophylaxis or treatment of inflammatory diseases in mucosa of oral cavity and the like
RU2004137651A (ru) * 2001-06-07 2005-10-10 Чю Консалтинг Инк. (US) Составы и способы профилактики и лечения афтозных язв и поражений вирусом герпес симплекс
TNSN02063A1 (en) * 2001-07-07 2005-12-23 Egyptian Natural Oil Co Natoil The medical effect of jojoba oil
US20060073174A1 (en) * 2001-08-16 2006-04-06 Access Pharmaceuticals, Inc. Adherent and erodible film to treat a moist surface of a body tissue
US6585997B2 (en) 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US20040029843A1 (en) * 2002-06-20 2004-02-12 Orapharma, Inc. Rapidly disintegrating formulations for treating or preventing mucositis
US6616923B1 (en) 2002-07-26 2003-09-09 Chiou Consulting, Inc. Aqueous compositions for facial cosmetics
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
US7258875B2 (en) * 2003-12-04 2007-08-21 Chiou Consulting, Inc. Compositions and methods for topical treatment of skin infection
US20060115266A1 (en) * 2004-12-01 2006-06-01 Gil Levi All-optical protection signaling systems and methods in optical communication networks
US20060252731A1 (en) * 2005-05-06 2006-11-09 Pfeiffer David F Methods of treating recurrent aphthous stomatitis
KR20090055606A (ko) 2006-09-27 2009-06-02 니코노범 에이비 지향성 용도
ITBO20090070A1 (it) * 2009-02-12 2010-08-12 Monica Bonucci Farmaco per la stomatite aftosa
CN103127086A (zh) * 2012-10-25 2013-06-05 吴俊华 Eryngiolide A在治疗或预防口腔溃疡药物中的应用
WO2020089249A1 (en) * 2018-10-29 2020-05-07 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Tetracycline complexes with sustained activity
EP3646852A1 (en) * 2018-10-29 2020-05-06 Fraunhofer Gesellschaft zur Förderung der Angewand Tetracycline complexes with sustained activity

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA743895A (en) * 1966-10-04 R. Bird Herbert Feeds for poultry and livestock
GB1561301A (en) * 1976-01-02 1980-02-20 Beecham Group Ltd Orally administrable pharmaceutical composition
US4748022A (en) * 1985-03-25 1988-05-31 Busciglio John A Topical composition
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
JPS6330421A (ja) * 1986-07-23 1988-02-09 Green Cross Corp:The 口腔部局所投与剤
US5049384A (en) * 1988-07-08 1991-09-17 Kim Young S Antibacterial composition for medical use and a process for the preparation thereof
SU1680180A1 (ru) * 1989-02-10 1991-09-30 Центральный научно-исследовательский институт стоматологии Средство дл лечени рецидивирующего афтозного стоматита
IL95642A0 (en) * 1989-09-15 1991-06-30 Pehrom Pharmaceutical Corp Topical preparations for treatment of ulcers and other lesions
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
EP0583470A4 (en) * 1992-01-10 1995-07-26 Obschestvo S Ogranichennoy Otv PHARMACEUTICAL COMPOSITION IN GRANULATE FORM AND PRODUCTION METHOD.
DE59307753D1 (de) * 1992-03-11 1998-01-15 Asta Medica Ag Tabletten, Granulate und Pellets mit hohem Gehalt an Wirkstoffen für hochkonzentrierte, feste Darreichungsformen
US5637616A (en) * 1993-06-18 1997-06-10 Arcturus Pharmaceutical Corporation Method for treating diseases mediated by proteases
AU1969595A (en) * 1994-02-24 1995-09-11 Ddr Enterprises Incorporated Topical composition for the treatment of aphthous ulcers containing an antimicrobial agent and a corticosteroid
GB2290707A (en) * 1994-06-28 1996-01-10 Georgi Stankov Pharmaceutical uses of Amphotericin B
GB2290708A (en) * 1994-06-28 1996-01-10 Georgi Stankov Pharmaceutical uses of polyene macrolides
DE4434929A1 (de) * 1994-06-28 1996-01-04 Georgi Dr Med Stankov Nystatin-Haftsalbe
WO1996024341A1 (en) * 1995-02-07 1996-08-15 Narayan Krishnarao Athanikar Concomitant treatment with bismuth and antibacterials
US5679339A (en) * 1995-06-27 1997-10-21 Keith; James Method of using IL-11 for treating spondyloarthropies
US6132768A (en) * 1995-07-05 2000-10-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors
CA2154103C (en) * 1995-07-18 1998-02-24 Samuel Simon Asculai Treatment of mucous membrane disease, trauma or condition and for the relief of pain

Also Published As

Publication number Publication date
EP1056442B1 (en) 2003-07-30
CA2320731A1 (en) 1999-08-26
CA2320731C (en) 2007-04-17
AU762585B2 (en) 2003-06-26
JP2002503684A (ja) 2002-02-05
CN1181821C (zh) 2004-12-29
EP1056442A1 (en) 2000-12-06
RU2211022C2 (ru) 2003-08-27
DE69816870D1 (de) 2003-09-04
DE69816870T2 (de) 2004-05-19
ATE245967T1 (de) 2003-08-15
CN1226425A (zh) 1999-08-25
AU7169798A (en) 1999-09-06
US5981499A (en) 1999-11-09
WO1999042083A1 (en) 1999-08-26

Similar Documents

Publication Publication Date Title
BR9815780A (pt) Antibióticos na forma de dosagem seca para otratamento de úlceras superficiais da mucosaoral
MX9302203A (es) Una composicion para el cuidado oral que comprende antagonistas de histamina-2.
EE200800028A (et) Farmatseutiline kompositsioon ja selle kasutamineravimi valmistamiseks, mis on ette n„htud insomnia raviks
TR200102067T2 (tr) Topikal formülasyonların mukoza boşluğuna verilmesi için aplikatör
BG102526A (bg) Твърди дозирани форми, съдържащи флурбипрофен
DE60034667D1 (de) Pharmazeutische zusammensetzung aus komplexen kohlenhydraten deren anwendung
FI971969A0 (fi) Peräpukamien hoitoon tarkoitettuja koostumuksia ja käyttömenetelmä
FI880425A0 (fi) Antibakteriellinen plakkia ja hammaskiveä estävä oraalinen koostumus
KR950702405A (ko) 구강 조성물(oral compositions)
NO20011502D0 (no) Fentanylsammensetning for behandling av akutt smerte
UA50719C2 (uk) Проліки для терапії пухлин і запальних захворювань
IT1254321B (it) Composizione farmaceutica per il trattamento e la prevenzione delle infiammazioni cutanee e della mucosa orale.
WO2001012128A3 (en) Antibacterial agents for the treatment of acute mucosal infections
SE9700885D0 (sv) New pharmaceutical formulation
AU3435189A (en) Topically applied gold organic complex
UA37278C2 (uk) Протикашльова фармацевтична композиція для перорального введення
DE69626987D1 (de) Pharmaceutische komposition
SE0004101D0 (sv) New use
NO970178D0 (no) Terpenoidderivater (sarcodictyiner) som er nyttige som antitumormidler
IL111805A0 (en) Pharmaceutical compositions comprising dimeticone for the treatment of aphthae
ES2086536T3 (es) Uso de ketorolaco para el tratamiento de la enfermedad periodontal.
ATE405276T1 (de) Pharmazeutische gel-zusammensetzung
ATE83657T1 (de) Pharmazeutische zusammensetzung.
DK0927031T3 (da) Farmaceutisk sammensætning indeholdende nimesulid til oral admnistration
ES2106907T3 (es) Agente para dejar de fumar.

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO DISPOSTO NOS ARTIGOS 8O E 13 DA LPI.