BR9813961A - Metodo para remover sais biliares de um paciente, polimero de polidialilamina e seus sais, e seu uso. - Google Patents
Metodo para remover sais biliares de um paciente, polimero de polidialilamina e seus sais, e seu uso.Info
- Publication number
- BR9813961A BR9813961A BR9813961-4A BR9813961A BR9813961A BR 9813961 A BR9813961 A BR 9813961A BR 9813961 A BR9813961 A BR 9813961A BR 9813961 A BR9813961 A BR 9813961A
- Authority
- BR
- Brazil
- Prior art keywords
- salts
- patient
- removing bile
- polymer
- polydiallylamine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
"MéTODO PARA REMOVER SAIS BILIARES DE UM PACIENTE, POLìMERO DE POLIDIALILAMINA E SEUS SAIS E SEU USO. " Método para remover sais biliares de um paciente, que inclui administrar ao paciente uma quantidade terapeuticamente eficaz de polímeros de polidialilamina não absorvível.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/964,536 US6083497A (en) | 1997-11-05 | 1997-11-05 | Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers |
| PCT/US1998/022605 WO1999022721A2 (en) | 1997-11-05 | 1998-10-26 | Unsubstituted polydiallylamine for treating hypercholesterolemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9813961A true BR9813961A (pt) | 2000-09-26 |
Family
ID=25508662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9813961-4A BR9813961A (pt) | 1997-11-05 | 1998-10-26 | Metodo para remover sais biliares de um paciente, polimero de polidialilamina e seus sais, e seu uso. |
Country Status (20)
| Country | Link |
|---|---|
| US (6) | US6083497A (pt) |
| EP (1) | EP1028717B1 (pt) |
| JP (1) | JP4649039B2 (pt) |
| KR (1) | KR20010031822A (pt) |
| CN (1) | CN1278180A (pt) |
| AR (1) | AR013742A1 (pt) |
| AT (1) | ATE235236T1 (pt) |
| AU (1) | AU746876B2 (pt) |
| BR (1) | BR9813961A (pt) |
| CA (1) | CA2309027C (pt) |
| DE (1) | DE69812681T2 (pt) |
| ES (1) | ES2196625T3 (pt) |
| HU (1) | HUP0004279A3 (pt) |
| IL (1) | IL135858A0 (pt) |
| NO (1) | NO20002172L (pt) |
| NZ (1) | NZ504216A (pt) |
| PL (1) | PL340296A1 (pt) |
| TW (1) | TW453878B (pt) |
| WO (1) | WO1999022721A2 (pt) |
| ZA (1) | ZA989673B (pt) |
Families Citing this family (58)
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| US5667775A (en) * | 1993-08-11 | 1997-09-16 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
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| US6083497A (en) * | 1997-11-05 | 2000-07-04 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers |
| US6221897B1 (en) * | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
| WO2001028527A2 (en) * | 1999-10-19 | 2001-04-26 | Geltex Pharmaceuticals, Inc. | Direct compression polymer tablet core |
| US6733780B1 (en) | 1999-10-19 | 2004-05-11 | Genzyme Corporation | Direct compression polymer tablet core |
| GB9927088D0 (en) | 1999-11-17 | 2000-01-12 | Secr Defence | Use of poly(diallylamine) polymers |
| FI113613B (fi) * | 1999-11-24 | 2004-05-31 | Eritocap Oy | Elintarvikekoostumukset ja menetelmiä niiden valmistamiseksi |
| WO2002085379A1 (en) * | 2001-04-18 | 2002-10-31 | Geltex Pharmaceuticals, Inc. | Method for improving vascular access in patients with vascular shunts |
| ES2268013T3 (es) * | 2001-04-18 | 2007-03-16 | Genzyme Corporation | Formas de polialilamina bajas de sal. |
| WO2002085380A1 (en) * | 2001-04-18 | 2002-10-31 | Geltex Pharmaceuticals, Inc. | Method for treating gout and reducing serum uric acid |
| KR20040018359A (ko) * | 2001-04-18 | 2004-03-03 | 젠자임 코포레이션 | 지방족 폴리아민으로 x 증후군을 치료하는 방법 |
| EP1923064B1 (en) | 2001-04-18 | 2017-06-28 | Genzyme Corporation | Use of amine polymer for lowering serum glucose |
| JP4499363B2 (ja) * | 2001-04-18 | 2010-07-07 | ジェンザイム コーポレーション | 血清グルコースの減少方法 |
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| US7223887B2 (en) * | 2001-12-18 | 2007-05-29 | The University Of British Columbia | Multivalent cationic lipids and methods of using same in the production of lipid particles |
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| BR0312426A (pt) * | 2002-07-03 | 2005-12-06 | Esperion Therapeutics Inc | Composição farmacêutica, métodos para tratar, prevenir ou controlar um colesterol, dislipidemia ou distúrbio relacionado, para reduzir ou evitar um efeito adverso associado com monoterapia de pantetina e para reduzir ou evitar um efeito adverso associado com monoterapia de segundo agente ativo, e, kit |
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| AT412473B (de) | 2003-01-15 | 2005-03-25 | Dsm Fine Chem Austria Gmbh | Verfahren zur kontinuierlichen trocknung von n- bzw. amino-, ammonium- oder spirobicyclische ammoniumgruppen haltigen polymeren |
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| EP1951266A2 (en) * | 2005-09-02 | 2008-08-06 | Genzyme Corporation | Method for removing phosphate and polymer used therefore |
| AR056499A1 (es) * | 2005-09-06 | 2007-10-10 | Serapis Farmaceuticals Ltd | Compuestos |
| US20070122375A1 (en) * | 2005-09-12 | 2007-05-31 | Council Of Scientific And Industrial Research | Bile acid sequestrant and process for preparation thereof |
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| EP2016114A2 (en) * | 2006-05-05 | 2009-01-21 | Genzyme Corporation | Amine condensation polymers as phosphate sequestrants |
| BRPI0715053A2 (pt) * | 2006-07-18 | 2013-03-19 | Genzyme Corp | composiÇço farmacÊutica, mÉtodo para tratar doenÇas, e, polÍmero |
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| CN102993348B (zh) * | 2011-09-09 | 2014-11-12 | 北大方正集团有限公司 | 一种烟酸司维拉姆及其制备方法和用途 |
| CN103012789B (zh) * | 2011-09-23 | 2015-02-25 | 北大方正集团有限公司 | 烟酸司维拉姆的制备方法 |
| EP2771003B1 (en) | 2011-10-28 | 2017-04-19 | Lumena Pharmaceuticals LLC | Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases |
| KR20190135545A (ko) | 2011-10-28 | 2019-12-06 | 루메나 파마수티컬즈, 인코포레이티드 | 고담혈증 및 담즙 정체성 간 질환 치료용 담즙산 재순환 억제제 |
| CN103030713A (zh) * | 2012-12-21 | 2013-04-10 | 江南大学 | 一种具有降血脂活性的低分子量葡聚糖-烟酸聚合物的制备方法 |
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-
1997
- 1997-11-05 US US08/964,536 patent/US6083497A/en not_active Expired - Lifetime
-
1998
- 1998-03-11 AR ARP980105512A patent/AR013742A1/es not_active Application Discontinuation
- 1998-10-23 ZA ZA989673A patent/ZA989673B/xx unknown
- 1998-10-26 ES ES98957370T patent/ES2196625T3/es not_active Expired - Lifetime
- 1998-10-26 HU HU0004279A patent/HUP0004279A3/hu unknown
- 1998-10-26 EP EP98957370A patent/EP1028717B1/en not_active Expired - Lifetime
- 1998-10-26 CN CN98810752A patent/CN1278180A/zh active Pending
- 1998-10-26 JP JP2000518655A patent/JP4649039B2/ja not_active Expired - Lifetime
- 1998-10-26 CA CA002309027A patent/CA2309027C/en not_active Expired - Lifetime
- 1998-10-26 AU AU13646/99A patent/AU746876B2/en not_active Expired
- 1998-10-26 WO PCT/US1998/022605 patent/WO1999022721A2/en not_active Ceased
- 1998-10-26 AT AT98957370T patent/ATE235236T1/de active
- 1998-10-26 BR BR9813961-4A patent/BR9813961A/pt not_active Application Discontinuation
- 1998-10-26 PL PL98340296A patent/PL340296A1/xx unknown
- 1998-10-26 NZ NZ504216A patent/NZ504216A/xx not_active IP Right Cessation
- 1998-10-26 KR KR1020007004892A patent/KR20010031822A/ko not_active Withdrawn
- 1998-10-26 IL IL13585898A patent/IL135858A0/xx unknown
- 1998-10-26 DE DE69812681T patent/DE69812681T2/de not_active Expired - Lifetime
- 1998-11-03 TW TW087118239A patent/TW453878B/zh not_active IP Right Cessation
-
1999
- 1999-05-13 US US09/311,103 patent/US6365186B1/en not_active Expired - Lifetime
- 1999-05-13 US US09/311,402 patent/US6264938B1/en not_active Expired - Lifetime
-
2000
- 2000-03-09 US US09/521,975 patent/US6248318B1/en not_active Expired - Lifetime
- 2000-04-27 NO NO20002172A patent/NO20002172L/no not_active Application Discontinuation
-
2001
- 2001-12-19 US US10/025,184 patent/US7638524B2/en not_active Expired - Fee Related
-
2009
- 2009-11-09 US US12/590,511 patent/US20100266526A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69812681D1 (de) | 2003-04-30 |
| ZA989673B (en) | 1999-05-11 |
| DE69812681T2 (de) | 2004-04-29 |
| AR013742A1 (es) | 2001-01-10 |
| JP4649039B2 (ja) | 2011-03-09 |
| HUP0004279A2 (hu) | 2002-03-28 |
| JP2001521890A (ja) | 2001-11-13 |
| AU1364699A (en) | 1999-05-24 |
| HUP0004279A3 (en) | 2002-04-29 |
| CA2309027C (en) | 2007-10-02 |
| CA2309027A1 (en) | 1999-05-14 |
| NO20002172D0 (no) | 2000-04-27 |
| TW453878B (en) | 2001-09-11 |
| CN1278180A (zh) | 2000-12-27 |
| US6083497A (en) | 2000-07-04 |
| EP1028717A2 (en) | 2000-08-23 |
| WO1999022721A2 (en) | 1999-05-14 |
| AU746876B2 (en) | 2002-05-02 |
| US6248318B1 (en) | 2001-06-19 |
| NO20002172L (no) | 2000-07-04 |
| ATE235236T1 (de) | 2003-04-15 |
| US20020155091A1 (en) | 2002-10-24 |
| PL340296A1 (en) | 2001-01-29 |
| US7638524B2 (en) | 2009-12-29 |
| US20100266526A1 (en) | 2010-10-21 |
| KR20010031822A (ko) | 2001-04-16 |
| US6365186B1 (en) | 2002-04-02 |
| EP1028717B1 (en) | 2003-03-26 |
| IL135858A0 (en) | 2001-05-20 |
| US6264938B1 (en) | 2001-07-24 |
| ES2196625T3 (es) | 2003-12-16 |
| WO1999022721A3 (en) | 1999-08-05 |
| NZ504216A (en) | 2002-11-26 |
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