BR9813588A - Processo para produção de uma composição adoçante contendo apm e referido derivado de apm, composição adoçante, e, adoçante - Google Patents
Processo para produção de uma composição adoçante contendo apm e referido derivado de apm, composição adoçante, e, adoçanteInfo
- Publication number
- BR9813588A BR9813588A BR9813588-0A BR9813588A BR9813588A BR 9813588 A BR9813588 A BR 9813588A BR 9813588 A BR9813588 A BR 9813588A BR 9813588 A BR9813588 A BR 9813588A
- Authority
- BR
- Brazil
- Prior art keywords
- apm
- sweetener
- composition containing
- derivative
- sweetener composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- -1 and Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 235000003599 food sweetener Nutrition 0.000 title 3
- 239000003765 sweetening agent Substances 0.000 title 3
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 abstract 9
- 108010011485 Aspartame Proteins 0.000 abstract 8
- 229960003438 aspartame Drugs 0.000 abstract 8
- 235000010357 aspartame Nutrition 0.000 abstract 8
- 239000000605 aspartame Substances 0.000 abstract 8
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 238000005932 reductive alkylation reaction Methods 0.000 abstract 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 229960004717 insulin aspart Drugs 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
- A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Seasonings (AREA)
- Peptides Or Proteins (AREA)
Abstract
"PROCESSO PARA PRODUçãO DE UMA COMPOSIçãO ADOçANTE CONTENDO APM E REFERIDO DERIVADO DE APM, COMPOSIçãO ADOçANTE, E, ADOçANTE". Uma excelente composição adoçante contendo aspartame (APM) e éster metílico de N-[N-(3,3- dimetilbutil)-L-<244>-aspartil]-L-fenilalanina e sendo similar a sacarose em propriedades de gosto, pode ser facilmente, uniformemente e eficientemente produzida em um alto rendimento e uma alta pureza no processo para produzir o N-(3,3-dimetilbutil)-APM (derivado de APM) pela alquilação redutiva de APM com 3,3-dimetilbutilaldeído, que compreende: a produção do derivado de APM a partir de uma porção do APM existente no sistema de reação por uso de 3,3-dimetilbutilaldeído em uma quantidade no máximo equimolar a APM na alquilação redutiva, então separando o agente redutor da mistura de reação líquida, e efetuando a cristalização seguido pela separação dos cristais assim precipitados.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9344778A JPH11169133A (ja) | 1997-12-15 | 1997-12-15 | アスパルテーム及びアスパルテーム誘導体を含有する甘味料組成物 |
| PCT/JP1998/005555 WO1999030575A1 (en) | 1997-12-15 | 1998-12-08 | Sweetener compositions containing aspartame and aspartame derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9813588A true BR9813588A (pt) | 2000-10-17 |
Family
ID=18371915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9813588-0A BR9813588A (pt) | 1997-12-15 | 1998-12-08 | Processo para produção de uma composição adoçante contendo apm e referido derivado de apm, composição adoçante, e, adoçante |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6444251B1 (pt) |
| EP (1) | EP1048223A4 (pt) |
| JP (1) | JPH11169133A (pt) |
| KR (1) | KR20010033122A (pt) |
| CN (1) | CN1282222A (pt) |
| BR (1) | BR9813588A (pt) |
| CA (1) | CA2310761C (pt) |
| WO (1) | WO1999030575A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010075419A (ko) | 1998-10-30 | 2001-08-09 | 에가시라 구니오 | 안정성이 우수한 아스파르탐 유도체 결정의 결정 석출법 |
| RU2244491C1 (ru) * | 2003-05-15 | 2005-01-20 | Общество с ограниченной ответственностью "Зеленый лист" | Подсластитель для пищевых продуктов |
| WO2012026499A1 (ja) * | 2010-08-25 | 2012-03-01 | 味の素株式会社 | アスパルチルジペプチドエステル誘導体の保存方法及び安定化剤 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2697844B1 (fr) * | 1992-11-12 | 1995-01-27 | Claude Nofre | Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation. |
| FR2719590B1 (fr) * | 1994-05-09 | 1996-07-26 | Claude Nofre | Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant. |
-
1997
- 1997-12-15 JP JP9344778A patent/JPH11169133A/ja active Pending
-
1998
- 1998-12-08 WO PCT/JP1998/005555 patent/WO1999030575A1/ja not_active Ceased
- 1998-12-08 EP EP98967081A patent/EP1048223A4/en not_active Withdrawn
- 1998-12-08 BR BR9813588-0A patent/BR9813588A/pt not_active IP Right Cessation
- 1998-12-08 KR KR1020007006494A patent/KR20010033122A/ko not_active Withdrawn
- 1998-12-08 CA CA002310761A patent/CA2310761C/en not_active Expired - Fee Related
- 1998-12-08 CN CN98812180A patent/CN1282222A/zh active Pending
-
2000
- 2000-06-15 US US09/594,039 patent/US6444251B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1282222A (zh) | 2001-01-31 |
| JPH11169133A (ja) | 1999-06-29 |
| US6444251B1 (en) | 2002-09-03 |
| CA2310761C (en) | 2008-02-05 |
| KR20010033122A (ko) | 2001-04-25 |
| WO1999030575A1 (en) | 1999-06-24 |
| EP1048223A4 (en) | 2001-09-12 |
| CA2310761A1 (en) | 1999-06-24 |
| EP1048223A1 (en) | 2000-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A,5A,6A,7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007. |
|
| B15K | Others concerning applications: alteration of classification |
Ipc: C07K 5/072 (2006.01), A23L 27/30 (2016.0 |