BR9811478A - Composições de polìmero-ácido tânico para a liberação controlada de agentes farmacêuticos particularmente na cavidade oral - Google Patents
Composições de polìmero-ácido tânico para a liberação controlada de agentes farmacêuticos particularmente na cavidade oralInfo
- Publication number
- BR9811478A BR9811478A BR9811478-6A BR9811478A BR9811478A BR 9811478 A BR9811478 A BR 9811478A BR 9811478 A BR9811478 A BR 9811478A BR 9811478 A BR9811478 A BR 9811478A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical agents
- oral cavity
- tannic acid
- controlled release
- polymer
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000013270 controlled release Methods 0.000 title abstract 3
- 239000008177 pharmaceutical agent Substances 0.000 title abstract 3
- 239000001263 FEMA 3042 Substances 0.000 title abstract 2
- 210000000214 mouth Anatomy 0.000 title abstract 2
- 229920002258 tannic acid Polymers 0.000 title abstract 2
- 229940033123 tannic acid Drugs 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 229920000642 polymer Polymers 0.000 abstract 2
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 abstract 1
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 abstract 1
- 235000015523 tannic acid Nutrition 0.000 abstract 1
- 229920001864 tannin Polymers 0.000 abstract 1
- 235000018553 tannin Nutrition 0.000 abstract 1
- 239000001648 tannin Substances 0.000 abstract 1
- 230000001256 tonic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Physiology (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"COMPOSIçõES DE POLìMERO-áCIDO TâNICO PARA A LIBERAçãO CONTROLADA DE AGENTES FARMACêUTICOS PARTICULARMENTE NA CAVIDADE ORAL" A presente invenção está orientada para composições de liberação controlada ou sustentada de agentes farmacêuticos ou outros. Os componentes essenciais nas composições da presente invenção incluem um ou mais polímeros e ácido tânico ou tanino. A liberação de agentes farmacêuticos ou outros agentes é por um período de tempo predeterminado e a uma concentração predeterminada. O campo de ação do agente é tópico, local ou sistêmico. Os polímeros são celulósicos ou proteináceos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89912197A | 1997-07-23 | 1997-07-23 | |
| PCT/US1998/015096 WO1999004764A1 (en) | 1997-07-23 | 1998-07-22 | Tannic acid-polymer compositions for controlled release of pharmaceutical agents, particularly in the oral cavity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9811478A true BR9811478A (pt) | 2000-08-15 |
Family
ID=25410514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9811478-6A BR9811478A (pt) | 1997-07-23 | 1998-07-22 | Composições de polìmero-ácido tânico para a liberação controlada de agentes farmacêuticos particularmente na cavidade oral |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1003483A1 (pt) |
| JP (1) | JP2001510788A (pt) |
| KR (1) | KR20010021911A (pt) |
| AU (1) | AU8578498A (pt) |
| BR (1) | BR9811478A (pt) |
| CA (1) | CA2296654A1 (pt) |
| HU (1) | HUP0002490A2 (pt) |
| IL (1) | IL134151A0 (pt) |
| NO (1) | NO20000284L (pt) |
| WO (1) | WO1999004764A1 (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001268722B8 (en) * | 2000-06-23 | 2005-09-29 | Teva Pharmaceutical Industries Ltd. | Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition |
| US6476006B2 (en) | 2000-06-23 | 2002-11-05 | Teva Pharmaceutical Industries, Ltd. | Composition and dosage form for delayed gastric release of alendronate and/or other bis-phosphonates |
| US7674480B2 (en) | 2000-06-23 | 2010-03-09 | Teva Pharmaceutical Industries Ltd. | Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition |
| US6881420B2 (en) | 2000-06-23 | 2005-04-19 | Teva Pharmaceutical Industries Ltd. | Compositions and dosage forms for gastric delivery of irinotecan and methods of treatment that use it to inhibit cancer cell proliferation |
| DE50014547D1 (de) * | 2000-09-01 | 2007-09-20 | Cognis Ip Man Gmbh | Mund- und Zahnpflegemittel |
| JP4820024B2 (ja) | 2001-01-10 | 2011-11-24 | 昭和薬品化工株式会社 | 局所麻酔用組成物 |
| JP5089840B2 (ja) * | 2001-09-25 | 2012-12-05 | 救急薬品工業株式会社 | ニコチン含有フィルム製剤 |
| CN1309425C (zh) * | 2001-11-05 | 2007-04-11 | 奥拉黑尔斯公司 | 用贴片治疗口腔溃疡以加速痊愈和缓解疼痛的方法 |
| ES2536713T3 (es) | 2003-03-12 | 2015-05-27 | Epitome Pharmaceuticals Limited | Composiciones para la piel lipófilas de rápida absorción y usos de las mismas |
| US20040185009A1 (en) * | 2003-03-19 | 2004-09-23 | Dexcel Pharma Technologies Ltd. | Composition and device for treating periodontal diseases |
| US8469036B2 (en) | 2003-11-07 | 2013-06-25 | U.S. Smokeless Tobacco Company Llc | Tobacco compositions |
| US8627828B2 (en) | 2003-11-07 | 2014-01-14 | U.S. Smokeless Tobacco Company Llc | Tobacco compositions |
| WO2005048965A2 (en) * | 2003-11-13 | 2005-06-02 | Wm. Wrigley Jr. Company | Method and composition for breath freshening |
| US7323169B2 (en) | 2004-04-23 | 2008-01-29 | Amgen Inc. | Sustained release formulations |
| US20100247653A1 (en) * | 2006-04-11 | 2010-09-30 | Hans Lautenschlager | Nanoparticles containing nicotine and/or cotinine, dispersions, and use thereof |
| US8642088B2 (en) | 2009-09-04 | 2014-02-04 | Wisconsin Alumni Research Foundation | Tannin-chitosan composites |
| KR101307367B1 (ko) | 2010-09-14 | 2013-09-25 | 주식회사 이노테라피 | 탄닌, 폴리에틸렌글리콜 및 물, 저급 알코올 또는 이들의 혼합물을 포함하는 접착제 조성물 |
| US8865198B2 (en) | 2010-10-25 | 2014-10-21 | Dexcel Pharma Technologies Ltd. | Method for treating a periodontal disease |
| FR2972327B1 (fr) * | 2011-03-11 | 2017-08-11 | Laboratoires Le Stum | Composition nutraceutique mucoadhesive comprenant une association d'antioxydants |
| GB2496654A (en) * | 2011-11-18 | 2013-05-22 | Reckitt & Colman Overseas | Self-assembling peptides |
| US20130158132A1 (en) * | 2011-12-19 | 2013-06-20 | Aida Salatinjants | Formulation Solution Adapted To Prolong Plasma Times Of Drugs In Mammals Including Humans |
| WO2015167257A1 (ko) * | 2014-04-29 | 2015-11-05 | 포항공과대학교 산학협력단 | 구강 도포용 조성물 및 그 제조 방법 |
| RU2606589C2 (ru) * | 2015-02-16 | 2017-01-10 | Александр Александрович Кролевец | Способ получения нанокапсул танина |
| US10532046B2 (en) * | 2015-12-03 | 2020-01-14 | Niconovum Usa, Inc. | Multi-phase delivery compositions and products incorporating such compositions |
| EP4013452A4 (en) * | 2019-08-16 | 2023-10-18 | AMD Pharma Ltd. | ADHESIVE DRUG DELIVERY FILM AND MICROPARTICLES THEREOF |
| US12234578B2 (en) | 2020-01-29 | 2025-02-25 | Wisconsin Alumni Research Foundation | Tannin composite fibers |
| US12303564B2 (en) | 2021-03-19 | 2025-05-20 | Wisconsin Alumni Research Foundation | Composite chitosan-tannin-active agent compositions and methods of making and using same |
| CN115477920A (zh) * | 2021-06-15 | 2022-12-16 | 西南大学 | 一种单宁酸基水下粘合剂制备方法及制品 |
| KR102836840B1 (ko) | 2022-04-13 | 2025-07-21 | 경북대학교 산학협력단 | 치아 수복을 위한 약물 서방성 자가 치유 코팅층 형성용 조성물 및 이의 제조방법 |
| CN117322671A (zh) * | 2023-11-01 | 2024-01-02 | 东莞市吉纯生物技术有限公司 | 一种烟碱脂质体及其制备方法与电子雾化液 |
| CN119488503B (zh) * | 2024-11-14 | 2025-06-27 | 沈阳盛京生物细胞研发中心有限公司 | 一种纳米型外泌体胶囊及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB104609A (en) * | 1916-06-05 | 1917-03-15 | Monneron & Guye | A Method of Manufacturing a Medicinal Aluminium Preparation. |
| GB918754A (en) * | 1959-08-14 | 1963-02-20 | Armour & Co | Improvements in or relating to corticotrophin preparations |
| GB2036750B (en) * | 1978-11-23 | 1983-05-05 | Payne M | Tannin complexes |
| JPS5846011A (ja) * | 1981-09-14 | 1983-03-17 | Kao Corp | 毛髪処理剤 |
| JPH01166763A (ja) * | 1987-12-22 | 1989-06-30 | Nitta Gelatin Inc | 医科用および歯科用硬化性材料 |
| WO1989010745A1 (en) * | 1988-05-02 | 1989-11-16 | Pomerantz, Edwin | Compositions and in situ methods for forming films on body tissue |
| JPH04114655A (ja) * | 1990-09-03 | 1992-04-15 | Shinonaga Kasei Kk | 医療用硬化組成物 |
| JPH04312522A (ja) * | 1991-04-08 | 1992-11-04 | Yoshiaki Kawashima | 徐放性錠剤の製造方法 |
| JP3496727B2 (ja) * | 1993-12-27 | 2004-02-16 | 救急薬品工業株式会社 | 製剤用基剤 |
| JPH08319232A (ja) * | 1995-03-22 | 1996-12-03 | Takeda Chem Ind Ltd | 粉粒状組成物 |
| JP2885668B2 (ja) * | 1995-09-29 | 1999-04-26 | 沢井製薬株式会社 | テプレノン製剤 |
-
1998
- 1998-07-22 BR BR9811478-6A patent/BR9811478A/pt not_active Application Discontinuation
- 1998-07-22 WO PCT/US1998/015096 patent/WO1999004764A1/en not_active Ceased
- 1998-07-22 CA CA002296654A patent/CA2296654A1/en not_active Abandoned
- 1998-07-22 JP JP2000503824A patent/JP2001510788A/ja not_active Withdrawn
- 1998-07-22 KR KR1020007000475A patent/KR20010021911A/ko not_active Withdrawn
- 1998-07-22 IL IL13415198A patent/IL134151A0/xx unknown
- 1998-07-22 HU HU0002490A patent/HUP0002490A2/hu unknown
- 1998-07-22 AU AU85784/98A patent/AU8578498A/en not_active Abandoned
- 1998-07-22 EP EP98936955A patent/EP1003483A1/en not_active Withdrawn
-
2000
- 2000-01-20 NO NO20000284A patent/NO20000284L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010021911A (ko) | 2001-03-15 |
| NO20000284L (no) | 2000-03-22 |
| AU8578498A (en) | 1999-02-16 |
| EP1003483A1 (en) | 2000-05-31 |
| IL134151A0 (en) | 2001-04-30 |
| JP2001510788A (ja) | 2001-08-07 |
| NO20000284D0 (no) | 2000-01-20 |
| HUP0002490A2 (hu) | 2000-12-28 |
| WO1999004764A1 (en) | 1999-02-04 |
| CA2296654A1 (en) | 1999-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |