BR9807048A - Processo aperfeiçoado para a preparação de halo-4-fenoxiquinolinas - Google Patents
Processo aperfeiçoado para a preparação de halo-4-fenoxiquinolinasInfo
- Publication number
- BR9807048A BR9807048A BR9807048-7A BR9807048A BR9807048A BR 9807048 A BR9807048 A BR 9807048A BR 9807048 A BR9807048 A BR 9807048A BR 9807048 A BR9807048 A BR 9807048A
- Authority
- BR
- Brazil
- Prior art keywords
- phenoxyquinolines
- halo
- preparation
- improved process
- improved
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 3
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- OFUFXTHGZWIDDB-UHFFFAOYSA-N 2-chloroquinoline Chemical compound C1=CC=CC2=NC(Cl)=CC=C21 OFUFXTHGZWIDDB-UHFFFAOYSA-N 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000012320 chlorinating reagent Substances 0.000 abstract 1
- 238000006482 condensation reaction Methods 0.000 abstract 1
- 229920000728 polyester Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Patente de Invenção: <B>"PROCESSO APERFEIçOADO PARA A PREPARAçãO DE HALO-4-FENOXIQUINOLINAS"<D>. A presente invenção refere-se a um processo aperfeiçoado e simplificado para a preparação de halo-4-fenoxiquinolinas, através do quel é usado cloreto de tionila como o agente de cloração para preparar o intermediário de cloroquinolina antes da reação de condensação final e ser usado um único solvente de poliéster inerte de alto ponto de ebulição ao longo de todo procedimento de reação.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3662397P | 1997-01-31 | 1997-01-31 | |
| PCT/US1998/000714 WO1998033774A1 (en) | 1997-01-31 | 1998-01-15 | Improved process for the preparation of halo-4-phenoxyquinolines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR9807048A true BR9807048A (pt) | 2000-03-28 |
| BR9807048B1 BR9807048B1 (pt) | 2009-08-11 |
Family
ID=21889659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9807048-7A BR9807048B1 (pt) | 1997-01-31 | 1998-01-15 | processo aperfeiçoado para a preparação de halo-4-fenoxiquinolinas. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5973153A (pt) |
| EP (1) | EP0960099B1 (pt) |
| JP (1) | JP4368948B2 (pt) |
| KR (1) | KR100692106B1 (pt) |
| CN (1) | CN1119331C (pt) |
| AT (1) | ATE237591T1 (pt) |
| AU (1) | AU729797B2 (pt) |
| BR (1) | BR9807048B1 (pt) |
| DE (1) | DE69813511T2 (pt) |
| DK (1) | DK0960099T3 (pt) |
| ES (1) | ES2191923T3 (pt) |
| HU (1) | HU228752B1 (pt) |
| IL (1) | IL131148A0 (pt) |
| WO (1) | WO1998033774A1 (pt) |
| ZA (1) | ZA98794B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2783826B1 (fr) * | 1998-09-29 | 2002-07-19 | Rhodia Chimie Sa | Procede de preparation de 4-hydroxyquinoleines et/ou formes tautomeres |
| FR2786483B1 (fr) | 1998-12-01 | 2001-02-16 | Rhodia Chimie Sa | Procede de preparation de 4-hydroxyquinoleines et/ou formes tautomeres |
| ZA200302088B (en) * | 2000-09-08 | 2004-03-15 | Dow Agrosciences Llc | Process to produce halo-4-phenoxyquinolines. |
| CN108689927B (zh) * | 2018-07-09 | 2020-07-03 | 陕西恒润化学工业有限公司 | 一种苯氧喹啉及其合成方法 |
| CN109225323B (zh) * | 2018-10-26 | 2021-07-27 | 闽江学院 | 磺酸基官能化有机/无机双阳离子-钒掺杂杂多酸阴离子复合杂化体及其合成与应用 |
| CN114621141A (zh) * | 2020-12-10 | 2022-06-14 | 帕潘纳(北京)科技有限公司 | 制备喹啉类化合物的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR7731M (pt) * | 1968-08-22 | 1970-03-09 | ||
| IL89029A (en) * | 1988-01-29 | 1993-01-31 | Lilly Co Eli | Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them |
| US5245036A (en) * | 1992-05-07 | 1993-09-14 | Dowelanco | Process for the preparation of 4-phenoxyquinoline compounds |
| CH685560A5 (de) * | 1993-12-07 | 1995-08-15 | Lonza Ag | Verfahren zur Herstellung von 4-Hydroxychinolinen. |
-
1998
- 1998-01-15 CN CN98802189A patent/CN1119331C/zh not_active Expired - Lifetime
- 1998-01-15 US US09/007,429 patent/US5973153A/en not_active Expired - Lifetime
- 1998-01-15 AT AT98902547T patent/ATE237591T1/de active
- 1998-01-15 BR BRPI9807048-7A patent/BR9807048B1/pt not_active IP Right Cessation
- 1998-01-15 DK DK98902547T patent/DK0960099T3/da active
- 1998-01-15 EP EP98902547A patent/EP0960099B1/en not_active Expired - Lifetime
- 1998-01-15 ES ES98902547T patent/ES2191923T3/es not_active Expired - Lifetime
- 1998-01-15 AU AU59179/98A patent/AU729797B2/en not_active Expired
- 1998-01-15 DE DE69813511T patent/DE69813511T2/de not_active Expired - Lifetime
- 1998-01-15 HU HU0001757A patent/HU228752B1/hu unknown
- 1998-01-15 KR KR1019997006910A patent/KR100692106B1/ko not_active Expired - Lifetime
- 1998-01-15 WO PCT/US1998/000714 patent/WO1998033774A1/en not_active Ceased
- 1998-01-15 JP JP53291298A patent/JP4368948B2/ja not_active Expired - Lifetime
- 1998-01-15 IL IL13114898A patent/IL131148A0/xx not_active IP Right Cessation
- 1998-01-30 ZA ZA9800794A patent/ZA98794B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0960099B1 (en) | 2003-04-16 |
| BR9807048B1 (pt) | 2009-08-11 |
| CN1119331C (zh) | 2003-08-27 |
| ZA98794B (en) | 1999-09-29 |
| US5973153A (en) | 1999-10-26 |
| KR20000070661A (ko) | 2000-11-25 |
| WO1998033774A1 (en) | 1998-08-06 |
| HU228752B1 (en) | 2013-05-28 |
| ATE237591T1 (de) | 2003-05-15 |
| DK0960099T3 (da) | 2003-08-11 |
| EP0960099A1 (en) | 1999-12-01 |
| ES2191923T3 (es) | 2003-09-16 |
| KR100692106B1 (ko) | 2007-03-12 |
| DE69813511D1 (de) | 2003-05-22 |
| CN1246112A (zh) | 2000-03-01 |
| DE69813511T2 (de) | 2003-11-13 |
| IL131148A0 (en) | 2001-01-28 |
| HUP0001757A2 (hu) | 2000-09-28 |
| AU5917998A (en) | 1998-08-25 |
| HUP0001757A3 (en) | 2002-12-28 |
| JP4368948B2 (ja) | 2009-11-18 |
| JP2001520642A (ja) | 2001-10-30 |
| AU729797B2 (en) | 2001-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 20/10/2009, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 20.10.2019 |