BR9608804A - Processos para sintetizar (1s,2r) indandiol para sintetizar (1s) amino (2r) indanol substancialmente isento de qualquer estereoisômero de bio-resolução para remover cis (1s,2r) indandiol de uma mistura de cis (1s,2r) indandiol e cis (1r,2s) indandiol e cultura pura - Google Patents
Processos para sintetizar (1s,2r) indandiol para sintetizar (1s) amino (2r) indanol substancialmente isento de qualquer estereoisômero de bio-resolução para remover cis (1s,2r) indandiol de uma mistura de cis (1s,2r) indandiol e cis (1r,2s) indandiol e cultura puraInfo
- Publication number
- BR9608804A BR9608804A BR9608804A BR9608804A BR9608804A BR 9608804 A BR9608804 A BR 9608804A BR 9608804 A BR9608804 A BR 9608804A BR 9608804 A BR9608804 A BR 9608804A BR 9608804 A BR9608804 A BR 9608804A
- Authority
- BR
- Brazil
- Prior art keywords
- indandiol
- cis
- stereoisomer
- synthesize
- bio
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
- C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/38—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36095P | 1995-06-20 | 1995-06-20 | |
| GBGB9602938.4A GB9602938D0 (en) | 1996-02-13 | 1996-02-13 | Conversion of indene |
| PCT/US1996/010445 WO1997000966A1 (fr) | 1995-06-20 | 1996-06-14 | Conversion d'indene en (1s)-amino-(2r)-indanol depourvu de tout stereo-isomere, par combinaison de bioconversion de dioxygenase et d'etapes chimiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9608804A true BR9608804A (pt) | 1999-02-17 |
Family
ID=26308684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9608804A BR9608804A (pt) | 1995-06-20 | 1996-06-14 | Processos para sintetizar (1s,2r) indandiol para sintetizar (1s) amino (2r) indanol substancialmente isento de qualquer estereoisômero de bio-resolução para remover cis (1s,2r) indandiol de uma mistura de cis (1s,2r) indandiol e cis (1r,2s) indandiol e cultura pura |
Country Status (5)
| Country | Link |
|---|---|
| CN (1) | CN1194006A (fr) |
| AR (1) | AR002536A1 (fr) |
| AU (1) | AU6180096A (fr) |
| BR (1) | BR9608804A (fr) |
| WO (1) | WO1997000966A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9420067D0 (en) * | 1994-10-05 | 1994-11-16 | Zeneca Ltd | Process |
| US5858737A (en) * | 1995-06-20 | 1999-01-12 | Merck & Co., Inc. | Conversion of indene to (1S)-amino-(2R)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps |
| US5824540A (en) * | 1995-06-20 | 1998-10-20 | Merck & Co., Inc. | Pseudomonas putida strain with dioxygenase activity |
| EP0874059A4 (fr) * | 1996-01-12 | 1999-10-27 | Nippon Steel Chemical Co | Procede de production de derives de l'indane |
| NL1005832C2 (nl) * | 1997-04-17 | 1998-10-20 | Dsm Nv | Werkwijze voor de bereiding van CIS-(1S,2R)-aminoindanol. |
| GB2336841A (en) | 1998-04-28 | 1999-11-03 | Merck & Co Inc | Preparation of cis-(is,2r)-indanediol by the microbial reduction of 1,2-indanedione |
| WO2000009659A1 (fr) * | 1998-08-13 | 2000-02-24 | Lonza Ag | Procede pour la production de derives d'indane |
| NL1010354C2 (nl) * | 1998-10-20 | 2000-04-25 | Dsm Biotech Gmbh | Bereiding van aminoalcoholen. |
| HRP20180282T1 (hr) * | 2008-04-17 | 2018-03-23 | Io Biotech Aps | Imunoterapija na bazi indoleamin 2, 3-dioksigenaze |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599985A (en) * | 1993-09-14 | 1997-02-04 | Sepracor, Inc. | Optically pure 1-amido-2-indanols |
| US5420353A (en) * | 1994-03-11 | 1995-05-30 | Merck & Co., Inc. | Regiospecific process to make cis-1-amino-2-alkanol from epoxide |
| GB9420067D0 (en) * | 1994-10-05 | 1994-11-16 | Zeneca Ltd | Process |
-
1996
- 1996-06-14 BR BR9608804A patent/BR9608804A/pt not_active Application Discontinuation
- 1996-06-14 AU AU61800/96A patent/AU6180096A/en not_active Abandoned
- 1996-06-14 WO PCT/US1996/010445 patent/WO1997000966A1/fr not_active Ceased
- 1996-06-14 CN CN96196419A patent/CN1194006A/zh active Pending
- 1996-06-20 AR ARP960103234A patent/AR002536A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6180096A (en) | 1997-01-22 |
| AR002536A1 (es) | 1998-03-25 |
| WO1997000966A1 (fr) | 1997-01-09 |
| CN1194006A (zh) | 1998-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| B09B | Decision: refusal |