BR9306345A - Métodos para suprimir a habilidade de células-t de um mamífero de proliferar e para suprimir resposta imune composições para uso na supressão da capacidade de células-t de proliferarem e na supressão de resposta imune - Google Patents
Métodos para suprimir a habilidade de células-t de um mamífero de proliferar e para suprimir resposta imune composições para uso na supressão da capacidade de células-t de proliferarem e na supressão de resposta imuneInfo
- Publication number
- BR9306345A BR9306345A BR9306345A BR9306345A BR9306345A BR 9306345 A BR9306345 A BR 9306345A BR 9306345 A BR9306345 A BR 9306345A BR 9306345 A BR9306345 A BR 9306345A BR 9306345 A BR9306345 A BR 9306345A
- Authority
- BR
- Brazil
- Prior art keywords
- mammal
- suppressing
- proliferate
- cells
- ability
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title abstract 8
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000028993 immune response Effects 0.000 title abstract 3
- 102000018713 Histocompatibility Antigens Class II Human genes 0.000 abstract 1
- 108010027412 Histocompatibility Antigens Class II Proteins 0.000 abstract 1
- 102000043131 MHC class II family Human genes 0.000 abstract 1
- 108091054438 MHC class II family Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000004044 response Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Transplantation (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87128992A | 1992-04-20 | 1992-04-20 | |
| US96177992A | 1992-10-15 | 1992-10-15 | |
| US97773792A | 1992-11-13 | 1992-11-13 | |
| US08/027,127 US5593698A (en) | 1990-10-31 | 1993-03-05 | Suppression of proliferative response and induction of tolerance with polymorphic class II MHC allopeptides |
| PCT/US1993/003708 WO1993020842A1 (en) | 1992-04-20 | 1993-04-20 | Suppression of proliferative response and induction of tolerance with polymorphic class ii mhc allopeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9306345A true BR9306345A (pt) | 1998-06-30 |
Family
ID=27487557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9306345A BR9306345A (pt) | 1992-04-20 | 1993-04-20 | Métodos para suprimir a habilidade de células-t de um mamífero de proliferar e para suprimir resposta imune composições para uso na supressão da capacidade de células-t de proliferarem e na supressão de resposta imune |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5593698A (pt) |
| EP (1) | EP0637249B1 (pt) |
| JP (1) | JPH07505892A (pt) |
| KR (1) | KR100275656B1 (pt) |
| AT (1) | ATE205400T1 (pt) |
| AU (1) | AU686101B2 (pt) |
| BR (1) | BR9306345A (pt) |
| CA (1) | CA2118502A1 (pt) |
| DE (1) | DE69330752D1 (pt) |
| HU (1) | HUT71310A (pt) |
| IL (1) | IL105472A (pt) |
| NO (1) | NO943967L (pt) |
| WO (1) | WO1993020842A1 (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL99699A (en) | 1990-10-10 | 2002-04-21 | Autoimmune Inc | Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes |
| US6156306A (en) * | 1994-08-17 | 2000-12-05 | Albert Einstein College Of Medicine Of Yeshiva University | Pancreatic β-cells for allogeneic transplantation without immunosuppression |
| GB9505784D0 (en) * | 1995-03-22 | 1995-05-10 | Lynxvale Ltd | Anti-tumour treatment |
| US7361331B2 (en) * | 1996-10-18 | 2008-04-22 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food | Plant bioreactors |
| US6617171B2 (en) * | 1998-02-27 | 2003-09-09 | The General Hospital Corporation | Methods for diagnosing and treating autoimmune disease |
| US6599710B1 (en) | 1999-03-10 | 2003-07-29 | The General Hospital Corporation | Treatment of autoimmune disease |
| WO2001076617A2 (en) * | 2000-03-15 | 2001-10-18 | Advanced Research And Technology Institute | Oral tolerance induction by collagen to prevent allograft rejection |
| US7348005B2 (en) * | 2000-03-15 | 2008-03-25 | Advanced Research And Technology Institute | Oral tolerance induction by collagen to prevent allograft rejection |
| ES2292594T3 (es) | 2000-05-24 | 2008-03-16 | The Government Of The Usa As Represented By The Secretary Of Department Of Health And Human Services | E-selectina para tratar o prevenir accidentes cerebrovasculares. |
| AU2001278637B2 (en) * | 2000-08-21 | 2006-05-25 | Apitope Technology (Bristol) Limited | Peptide selection method |
| US7582313B2 (en) * | 2002-06-27 | 2009-09-01 | The General Hospital Corporation | Methods of organ regeneration using Hox 11-expressing pluripotent cells |
| US7628988B2 (en) | 2002-06-27 | 2009-12-08 | The General Hospital Corporation | Methods and compositions for treating type 1 diabetes |
| AU2003290948A1 (en) * | 2002-11-15 | 2004-06-15 | The General Hospital Corporation | Screening methods to identify treatments for autoimmune disease |
| US20080102054A1 (en) * | 2005-01-18 | 2008-05-01 | Faustman Denise L | Compositions Containing Agm Cells And Methods Of Use Thereof |
| GB0710529D0 (en) | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| EP2286833A3 (en) | 2007-08-15 | 2011-09-14 | Circassia Limited | Peptides for desensibilization against allergens |
| ES2885423T3 (es) | 2013-02-07 | 2021-12-13 | Massachusetts Gen Hospital | Procedimientos para la expansión o el empobrecimiento de células T reguladoras |
| KR102393711B1 (ko) | 2013-10-17 | 2022-05-04 | 더 제너럴 하스피탈 코포레이션 | 자가면역 질환의 치료에 반응하는 대상체의 식별 방법 및 그의 치료를 위한 조성물 |
| EP3126374B1 (en) * | 2014-04-01 | 2018-11-07 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An isolated donor mhc-derived peptide and uses thereof |
| CN107849142B (zh) | 2015-05-15 | 2022-04-26 | 综合医院公司 | 拮抗性抗肿瘤坏死因子受体超家族抗体 |
| US20190135929A1 (en) | 2015-08-28 | 2019-05-09 | The General Hospital Corporation | Agonistic anti-tumor necrosis factor receptor 2 antibodies |
| WO2017059132A1 (en) | 2015-09-29 | 2017-04-06 | The General Hospital Corporation | Methods of treating and diagnosing disease using biomarkers for bcg therapy |
| EP3455262A4 (en) | 2016-05-13 | 2020-04-08 | The General Hospital Corporation | ANTAGONIST ANTIBODIES OF THE NECROSIS FACTOR RECEPTOR SUPERFAMILY AGAINST TUMORS |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364762A (en) * | 1990-03-21 | 1994-11-15 | Board Of Trustees Of The Leland Stanford Junior University | Major histocompatibility complex (MHC) molecules |
-
1993
- 1993-03-05 US US08/027,127 patent/US5593698A/en not_active Expired - Fee Related
- 1993-04-20 JP JP5518673A patent/JPH07505892A/ja not_active Ceased
- 1993-04-20 WO PCT/US1993/003708 patent/WO1993020842A1/en not_active Ceased
- 1993-04-20 EP EP93910671A patent/EP0637249B1/en not_active Expired - Lifetime
- 1993-04-20 BR BR9306345A patent/BR9306345A/pt not_active Application Discontinuation
- 1993-04-20 CA CA002118502A patent/CA2118502A1/en not_active Abandoned
- 1993-04-20 HU HU9403006A patent/HUT71310A/hu unknown
- 1993-04-20 KR KR1019940703715A patent/KR100275656B1/ko not_active Expired - Fee Related
- 1993-04-20 DE DE69330752T patent/DE69330752D1/de not_active Expired - Lifetime
- 1993-04-20 AT AT93910671T patent/ATE205400T1/de not_active IP Right Cessation
- 1993-04-20 AU AU41083/93A patent/AU686101B2/en not_active Ceased
- 1993-04-20 IL IL10547293A patent/IL105472A/en not_active IP Right Cessation
-
1994
- 1994-10-19 NO NO943967A patent/NO943967L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU686101B2 (en) | 1998-02-05 |
| KR950701228A (ko) | 1995-03-23 |
| NO943967D0 (no) | 1994-10-19 |
| ATE205400T1 (de) | 2001-09-15 |
| HUT71310A (en) | 1995-11-28 |
| EP0637249A4 (en) | 1997-01-08 |
| DE69330752D1 (de) | 2001-10-18 |
| JPH07505892A (ja) | 1995-06-29 |
| CA2118502A1 (en) | 1993-10-28 |
| WO1993020842A1 (en) | 1993-10-28 |
| IL105472A0 (en) | 1993-08-18 |
| US5593698A (en) | 1997-01-14 |
| EP0637249A1 (en) | 1995-02-08 |
| EP0637249B1 (en) | 2001-09-12 |
| HU9403006D0 (en) | 1994-12-28 |
| IL105472A (en) | 1999-06-20 |
| KR100275656B1 (ko) | 2000-12-15 |
| AU4108393A (en) | 1993-11-18 |
| NO943967L (no) | 1994-10-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal | ||
| FC | Decision: refusal |