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BR8907798A - Sequencia recombinavel de dna,sistema de expressao recombinavel,celula hospedeira recombinavel,processo para produzir proteina humana,proteina humana,processo para produzir proteina murina,proteinas murina,proteinas tendo adipsina e atividade em relacao ao complemento d em seres humanos,proteina,composicao farmaceutica,preparacao de anticorpo,processo para diagnosticar deficiencia de adipsina ou complemento d.processo para tratar deficiencia de adipsina,processo para proteger mamiferos,processo para controle de obesidade,processo para controlar obesidade em mamiferos - Google Patents

Sequencia recombinavel de dna,sistema de expressao recombinavel,celula hospedeira recombinavel,processo para produzir proteina humana,proteina humana,processo para produzir proteina murina,proteinas murina,proteinas tendo adipsina e atividade em relacao ao complemento d em seres humanos,proteina,composicao farmaceutica,preparacao de anticorpo,processo para diagnosticar deficiencia de adipsina ou complemento d.processo para tratar deficiencia de adipsina,processo para proteger mamiferos,processo para controle de obesidade,processo para controlar obesidade em mamiferos

Info

Publication number
BR8907798A
BR8907798A BR898907798A BR8907798A BR8907798A BR 8907798 A BR8907798 A BR 8907798A BR 898907798 A BR898907798 A BR 898907798A BR 8907798 A BR8907798 A BR 8907798A BR 8907798 A BR8907798 A BR 8907798A
Authority
BR
Brazil
Prior art keywords
recombinable
adipsin
deficiency
proteins
obesity
Prior art date
Application number
BR898907798A
Other languages
English (en)
Inventor
Jeffrey S Flier
Bruce M Spiegelman
Barry M Rosen
R Tyler White
Original Assignee
Beth Israel Hospital
Dana Farber Cancer Inst Inc
Metabolic Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beth Israel Hospital, Dana Farber Cancer Inst Inc, Metabolic Biosystems Inc filed Critical Beth Israel Hospital
Publication of BR8907798A publication Critical patent/BR8907798A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
BR898907798A 1988-11-30 1989-11-21 Sequencia recombinavel de dna,sistema de expressao recombinavel,celula hospedeira recombinavel,processo para produzir proteina humana,proteina humana,processo para produzir proteina murina,proteinas murina,proteinas tendo adipsina e atividade em relacao ao complemento d em seres humanos,proteina,composicao farmaceutica,preparacao de anticorpo,processo para diagnosticar deficiencia de adipsina ou complemento d.processo para tratar deficiencia de adipsina,processo para proteger mamiferos,processo para controle de obesidade,processo para controlar obesidade em mamiferos BR8907798A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/277,963 US5223425A (en) 1987-04-02 1988-11-30 DNA encoding human adipsin with complement D activity
PCT/US1989/005374 WO1990006365A1 (en) 1988-11-30 1989-11-21 Recombinant proteins with adipsin and complement d activities

Publications (1)

Publication Number Publication Date
BR8907798A true BR8907798A (pt) 1991-08-27

Family

ID=23063108

Family Applications (1)

Application Number Title Priority Date Filing Date
BR898907798A BR8907798A (pt) 1988-11-30 1989-11-21 Sequencia recombinavel de dna,sistema de expressao recombinavel,celula hospedeira recombinavel,processo para produzir proteina humana,proteina humana,processo para produzir proteina murina,proteinas murina,proteinas tendo adipsina e atividade em relacao ao complemento d em seres humanos,proteina,composicao farmaceutica,preparacao de anticorpo,processo para diagnosticar deficiencia de adipsina ou complemento d.processo para tratar deficiencia de adipsina,processo para proteger mamiferos,processo para controle de obesidade,processo para controlar obesidade em mamiferos

Country Status (9)

Country Link
US (1) US5223425A (pt)
JP (1) JPH04505098A (pt)
AU (1) AU4808190A (pt)
BR (1) BR8907798A (pt)
DK (1) DK103091A (pt)
FI (1) FI912586A7 (pt)
IL (1) IL92504A0 (pt)
WO (1) WO1990006365A1 (pt)
ZA (1) ZA899161B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994012645A2 (en) * 1992-11-25 1994-06-09 University Of Pittsburgh Of The Commonwealth System Of Higher Education cDNA CLONE FOR HUMAN INDUCIBLE NITRIC OXYDE SYNTHASE AND PROCESS FOR PREPARING SAME
US6310034B1 (en) 1993-05-21 2001-10-30 Ut-Battelle, Llc Agouti polypeptide compositions
US5843652A (en) * 1993-05-21 1998-12-01 Lockheed Martin Energy Systems, Inc. Isolation and characterization of Agouti: a diabetes/obesity related gene
US6150152A (en) * 1993-05-28 2000-11-21 Washington University Human macrophage metalloelastase
US5869330A (en) * 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
WO2002013854A1 (en) * 2000-08-11 2002-02-21 Temple University Of The Commonwealth System Of Higher Education Obesity controlling method
US7737109B2 (en) * 2000-08-11 2010-06-15 Temple University Of The Commonwealth System Of Higher Education Obesity controlling method
US6867189B2 (en) * 2001-07-26 2005-03-15 Genset S.A. Use of adipsin/complement factor D in the treatment of metabolic related disorders
CA2499843A1 (en) * 2002-09-25 2004-04-08 Genentech, Inc. Novel compositions and methods for the treatment of psoriasis
US20060263774A1 (en) * 2002-11-01 2006-11-23 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
EP1572116A4 (en) * 2002-11-26 2007-12-12 Genentech Inc COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE DISEASES
WO2007141004A1 (en) * 2006-06-09 2007-12-13 Bayer Healthcare Ag Use of adipsin (adn) as a therapeutic or diagnostic target
FR2966734B1 (fr) * 2010-10-29 2014-07-18 Max Rombi Composition comprenant au moins une enzyme proteolytique pour son utilisation pour empecher la synthese des triglycerides
CN103760341B (zh) * 2014-01-28 2017-05-31 成都创宜生物科技有限公司 以Adipsin作为标志物制备检测工具的应用及检测工具
US10328131B2 (en) 2014-03-13 2019-06-25 Dana-Farber Cancer Institute, Inc. Compositions and methods for regulating pancreatic beta cell function using adipsin
EP4032543A1 (en) * 2021-01-20 2022-07-27 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Peptides from the sequence of the complement factor d for medical use, especially for the treatment of ebv-associated diseases
US12252629B2 (en) 2021-10-28 2025-03-18 Kismet Technologies Inc. Electronic device with self-disinfecting touch screen and method of manufacture

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684623A (en) * 1985-05-02 1987-08-04 The Board Of Trustees Of The Cetus Corporation Use of tumor necrosis factor as a weight regulator

Also Published As

Publication number Publication date
DK103091A (da) 1991-07-30
IL92504A0 (en) 1990-08-31
WO1990006365A1 (en) 1990-06-14
US5223425A (en) 1993-06-29
FI912586A0 (fi) 1991-05-29
ZA899161B (en) 1990-09-26
FI912586A7 (fi) 1991-05-29
AU4808190A (en) 1990-06-26
JPH04505098A (ja) 1992-09-10
DK103091D0 (da) 1991-05-30

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Legal Events

Date Code Title Description
FD3 Appl. lapsed due to non-payment of renewal fee
B15K Others concerning applications: alteration of classification

Ipc: C12N 9/64 (2006.01), C07K 16/40 (2006.0