BR0309375A - Treatment of metabolic syndrome - Google Patents
Treatment of metabolic syndromeInfo
- Publication number
- BR0309375A BR0309375A BR0309375-1A BR0309375A BR0309375A BR 0309375 A BR0309375 A BR 0309375A BR 0309375 A BR0309375 A BR 0309375A BR 0309375 A BR0309375 A BR 0309375A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- metabolic syndrome
- metformin
- analog
- growth hormone
- Prior art date
Links
- 208000001145 Metabolic Syndrome Diseases 0.000 title abstract 3
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 title abstract 3
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 102000018997 Growth Hormone Human genes 0.000 abstract 1
- 108010051696 Growth Hormone Proteins 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000122 growth hormone Substances 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 abstract 1
- 229960003105 metformin Drugs 0.000 abstract 1
- 230000001235 sensitizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"TRATAMENTO DE SìNDROME METABóLICA". A presente invenção refere-se ao uso de um hormónio de crescimento ou um seu análogo com um agente de sensibilização de insulina (por exemplo, metformin) no tratamento de síndrome metabólica."TREATMENT OF METABOLIC SYNDROME". The present invention relates to the use of a growth hormone or analog thereof with an insulin sensitizing agent (e.g. metformin) in the treatment of metabolic syndrome.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0209642A GB0209642D0 (en) | 2002-04-26 | 2002-04-26 | Metabolic syndrome |
| GB0218912A GB0218912D0 (en) | 2002-08-14 | 2002-08-14 | Metabolic syndrome |
| PCT/EP2003/004357 WO2003090784A1 (en) | 2002-04-26 | 2003-04-24 | Treatment of metabolic syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0309375A true BR0309375A (en) | 2005-03-29 |
Family
ID=29272006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0309375-1A BR0309375A (en) | 2002-04-26 | 2003-04-24 | Treatment of metabolic syndrome |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1499357A1 (en) |
| JP (1) | JP2005523915A (en) |
| KR (1) | KR20040101545A (en) |
| CN (1) | CN1646167A (en) |
| AU (1) | AU2003227683A1 (en) |
| BR (1) | BR0309375A (en) |
| CA (1) | CA2483005A1 (en) |
| IL (1) | IL164670A0 (en) |
| MX (1) | MXPA04010544A (en) |
| PL (1) | PL372900A1 (en) |
| WO (1) | WO2003090784A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2406493C1 (en) * | 2009-05-27 | 2010-12-20 | Илья Николаевич Медведев | Method for normalisation of adenosine diphosphate and adenosine triphosphate thrombocyte secretion activity in patients with arterial hypertension and impaired glucose tolerance |
| RU2016101363A (en) * | 2010-02-08 | 2018-11-21 | Прэари Фармасьютикалз, Ллк | METHOD FOR TREATING DISEASES ASSOCIATED WITH Glucocorticoid Insensitivity |
-
2003
- 2003-04-24 JP JP2003587413A patent/JP2005523915A/en active Pending
- 2003-04-24 EP EP03725104A patent/EP1499357A1/en not_active Withdrawn
- 2003-04-24 WO PCT/EP2003/004357 patent/WO2003090784A1/en not_active Ceased
- 2003-04-24 CA CA002483005A patent/CA2483005A1/en not_active Abandoned
- 2003-04-24 BR BR0309375-1A patent/BR0309375A/en not_active IP Right Cessation
- 2003-04-24 AU AU2003227683A patent/AU2003227683A1/en not_active Abandoned
- 2003-04-24 MX MXPA04010544A patent/MXPA04010544A/en active IP Right Grant
- 2003-04-24 CN CNA038088312A patent/CN1646167A/en active Pending
- 2003-04-24 PL PL03372900A patent/PL372900A1/en not_active Application Discontinuation
- 2003-04-24 KR KR10-2004-7016843A patent/KR20040101545A/en not_active Withdrawn
-
2004
- 2004-10-18 IL IL16467004A patent/IL164670A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL164670A0 (en) | 2005-12-18 |
| JP2005523915A (en) | 2005-08-11 |
| PL372900A1 (en) | 2005-08-08 |
| EP1499357A1 (en) | 2005-01-26 |
| CA2483005A1 (en) | 2003-11-06 |
| MXPA04010544A (en) | 2005-08-16 |
| WO2003090784A1 (en) | 2003-11-06 |
| KR20040101545A (en) | 2004-12-02 |
| CN1646167A (en) | 2005-07-27 |
| AU2003227683A1 (en) | 2003-11-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A,6A E 7A ANUIDADES. |
|
| B08J | Incorrect entry in the gazette republished [chapter 8.10 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2051 DE 27/04/2010. TEXTO CORRETO: REFERENTE A 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.10 DA RPI 2068 DE 24/08/2010. |