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BR0307018A - Corpos e veìculos farmaceuticamente aceitáveis de fosfato-glicerol - Google Patents

Corpos e veìculos farmaceuticamente aceitáveis de fosfato-glicerol

Info

Publication number
BR0307018A
BR0307018A BR0307018-2A BR0307018A BR0307018A BR 0307018 A BR0307018 A BR 0307018A BR 0307018 A BR0307018 A BR 0307018A BR 0307018 A BR0307018 A BR 0307018A
Authority
BR
Brazil
Prior art keywords
bodies
synthetic
vehicles
pharmaceutically acceptable
relates
Prior art date
Application number
BR0307018-2A
Other languages
English (en)
Inventor
Anthony E Bolton
Arkady Mandel
Original Assignee
Vasogen Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vasogen Ireland Ltd filed Critical Vasogen Ireland Ltd
Publication of BR0307018A publication Critical patent/BR0307018A/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G19/00—Compounds of tin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G15/00—Compounds of gallium, indium or thallium
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/24—Electrically-conducting paints

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Nanotechnology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)

Abstract

"CORPOS E VEìCULOS FARMACEUTICAMENTE ACEITáVEIS DE FOSFATO-GLICEROL". A presente invenção se refere a composições sintéticas e semi-sintéticas tridimensionais tendo atividade biológica e aos usos das mesmas no tratamento e/ou profilaxia de vários distúrbios em pacientes mamíferos. Mais particularmente, ela se refere a preparados e usos de corpos sintéticos e semi-sintéticos, tais como lipossomas os quais, após introdução no corpo de um paciente, produzem efeitos, anti-inflamatórios, órgão-protetores e regulatórios imunes benéficos. A invenção também se refere a tratamentos e composições para alívio de doenças inflamatórias e autoimunes e seus sintomas.
BR0307018-2A 2002-01-21 2003-01-21 Corpos e veìculos farmaceuticamente aceitáveis de fosfato-glicerol BR0307018A (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CA002368656A CA2368656A1 (en) 2002-01-21 2002-01-21 Receptor-ligand pairing for anti-inflammatory response
US5138102A 2002-01-22 2002-01-22
US35142702P 2002-01-28 2002-01-28
US36462002P 2002-03-18 2002-03-18
US37210602P 2002-04-15 2002-04-15
US40085702P 2002-08-02 2002-08-02
PCT/CA2003/000065 WO2003061667A1 (en) 2002-01-21 2003-01-21 Pharmaceutically acceptable phosphate-glycerol carrying bodies

Publications (1)

Publication Number Publication Date
BR0307018A true BR0307018A (pt) 2005-02-09

Family

ID=27617925

Family Applications (2)

Application Number Title Priority Date Filing Date
BR0307018-2A BR0307018A (pt) 2002-01-21 2003-01-21 Corpos e veìculos farmaceuticamente aceitáveis de fosfato-glicerol
BR0307041-7A BR0307041A (pt) 2002-01-21 2003-01-21 Corpos de fosfolipìdio e uso dos mesmos no tratamento de doenças inflamatórias e autoimunes

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR0307041-7A BR0307041A (pt) 2002-01-21 2003-01-21 Corpos de fosfolipìdio e uso dos mesmos no tratamento de doenças inflamatórias e autoimunes

Country Status (14)

Country Link
US (3) US20040013718A1 (pt)
EP (2) EP1467741A1 (pt)
JP (2) JP2005515242A (pt)
KR (1) KR20040089118A (pt)
CN (1) CN1620301A (pt)
AR (2) AR047005A1 (pt)
BR (2) BR0307018A (pt)
CA (5) CA2368656A1 (pt)
EA (1) EA007426B1 (pt)
MA (1) MA27168A1 (pt)
MX (1) MXPA04007042A (pt)
PE (1) PE20030973A1 (pt)
TW (2) TW200302281A (pt)
WO (3) WO2003061667A1 (pt)

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US20050058698A1 (en) * 2002-01-21 2005-03-17 Nolan Yvonne Mairead Pharmaceutically acceptable phosphate-glycerol carrying bodies and uses relating to Parkinson's Disease
WO2004082688A1 (en) * 2003-03-20 2004-09-30 Vasogen Ireland Limited Phosphatidylglycerol (pg) receptor agonists and antagonists
US20070238708A1 (en) * 2003-07-21 2007-10-11 Vasogen Ireland Limited Acute Inflammatory Condition Treatment
US20060008517A1 (en) * 2004-07-09 2006-01-12 Lynch Marina A Treatment of age-related memory impairment
EA200700626A1 (ru) * 2004-09-15 2007-10-26 Васоджен Айеленд Лимитед Лечение множественного склероза
WO2006107107A1 (ja) * 2005-04-01 2006-10-12 Fumitaka Ohsuzu リン脂質小胞体を含む心筋保護剤および虚血・再潅流時の心筋障害を予防する方法
EP1928420A1 (en) * 2005-09-26 2008-06-11 Vasogen Ireland Limited Treatment of inflammation and vascular abnormalities of the eye
JP5815915B2 (ja) * 2005-10-11 2015-11-17 ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 過活動膀胱障害の治療のためのスフィンゴミエリンリポソーム
WO2007131329A1 (en) * 2006-05-12 2007-11-22 Vasogen Ireland Limited Treatment of ubiquitin-proteasome system dysfunction related disorders
AU2010283998B2 (en) * 2009-08-21 2015-01-29 Targeted Delivery Technologies Limited Vesicular formulations
GB201205642D0 (en) 2012-03-29 2012-05-16 Sequessome Technology Holdings Ltd Vesicular formulations
RU2672106C2 (ru) * 2012-06-14 2018-11-12 Университэт Берн Специально разработанные липосомы для лечения бактериальных инфекций
JP6417648B2 (ja) * 2013-07-30 2018-11-07 株式会社豊田中央研究所 エタノールアミンリン酸の利用
EP3135297A4 (en) * 2014-04-04 2018-02-07 Osaka University Drug delivery promoter containing substance for activating lysophospholipid receptors
WO2016185816A1 (ja) * 2015-05-18 2016-11-24 不二製油グループ本社株式会社 ＩＬ－１β産生抑制作用を有する食品添加用組成物
CA3026484A1 (en) 2015-06-30 2017-01-05 Sequessome Technology Holdings Limited Multiphasic compositions comprising a collodial dispersion and uses thereof
CN110636839B (zh) 2017-03-02 2023-06-27 康柏辛股份有限公司 抑制生物膜形成的脂质体
CN115531399A (zh) * 2022-09-15 2022-12-30 首都医科大学 溶血磷脂酰胆碱在治疗阿尔茨海默病中的应用

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US20080160074A1 (en) 2008-07-03
CA2473490A1 (en) 2003-07-31
MXPA04007042A (es) 2005-06-20
TW200302735A (en) 2003-08-16
TWI283181B (en) 2007-07-01
EP1467741A1 (en) 2004-10-20
CN1620301A (zh) 2005-05-25
JP2005515243A (ja) 2005-05-26
CA2471740A1 (en) 2003-07-31
US20030175334A1 (en) 2003-09-18
US20040013718A1 (en) 2004-01-22
CA2368656A1 (en) 2003-07-21
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EP1467740A1 (en) 2004-10-20
PE20030973A1 (es) 2003-12-09
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WO2003061667A1 (en) 2003-07-31
JP2005515242A (ja) 2005-05-26
CA2416791A1 (en) 2003-07-21
CA2473395A1 (en) 2003-07-31
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WO2003061620A2 (en) 2003-07-31
BR0307041A (pt) 2004-10-26

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