BE1031771B1 - Fungicide composition - Google Patents

Abstract

This document discloses agricultural compositions comprising difenoconazole. Such compositions exhibit stability over a long period of time and are therefore more flexible in storage and use.

Description

Fungicide composition

Description

Technical domain

The present invention relates to stable compositions comprising difenoconazole and the use of such compositions for controlling, preventing and/or treating phytopathogenic fungi in agricultural crops.

State of the art

Difenoconazole is a broad spectrum triazole fungicide that controls a wide variety of foliar, seed and soil-borne fungi — including members of the

Aschomycetes, Basidomycetes and Deuteromycetes.

CH3 pe 9 (0 ÆN

N. —

Ci N

CI

Difenoconazol

Summary of invention

The aim of this invention is to provide commercially viable products of formulations with a high loading of difenoconazole.

Generally it is desirable to provide a higher concentration of difenoconazole, as the end user can adjust the amount of active ingredient applied to the field by adjusting the dilution rate, and avoid having to handle a large volume of product.

Furthermore, it is desirable to provide concentrates containing difenoconazole in as high a concentration as possible, because the higher the concentration, the more active ingredient is present in a given volume, which reduces transportation costs and makes it possible to prepare large volumes of final solution from small volumes of concentrate by simply adding water.

Furthermore, existing “low load” formulations are EC formulations, solvent based, and the switch to SC and “high load” not only offers the advantage of obtaining a more concentrated product, and therefore less packaging, but also that the solvent has now been replaced by water, which has a positive impact on the environment.

Consequently, it is desirable to increase the maximum loading of difenoconazole that can be successfully formulated into a commercially viable product.

Surprisingly, it has been found that in compositions according to the present invention, the degradation of active ingredient and the consequent formation of its degradation products is prevented or delayed, i.e. the stability of the compositions is maintained for a longer period of time and flexible storage and handling is obtained.

According to the present invention, stable compositions comprise: a) difenoconazole in an amount of 400 - 600 g/L, b) one or more dispersants in an amount of 50 - 100 g/L,

Cc) thickeners in a quantity of 0,1 — 50 g/L, d) one or more agents selected from antifoam agents and/or biocides in a quantity of 2 — 15 g/L, e) water in a quantity of 200 — 600 g/L.

In one aspect, stable compositions of the present invention comprise: a) difenoconazole in an amount of 500 g/L, b) one or more dispersants in an amount of 50 - 100 g/L,

Cc) one or more thickeners in a quantity of 0,1 — 50 g/L, d) one or more agents selected from antifoam agents and/or biocides in a quantity of 2 — 15 g/L, €) water in a quantity of 400 — 500 g/L.

Such compositions have a preventive and curative effect against numerous pathogenic fungi, such as Affernaria, Ascochyta, Cercospora, Cercosporidium, Colletotrichum, Guignardia,

Mycosphaerella, Phoma, Ramularia, Rhizoctonia, Septoria, Uncinula, Venturia spp., Erysiphaceae,

Uredinales in fruits, potatoes, sugar beets, rapeseed for oil, bananas, cereals, rice, soybeans, ornamentals and vegetables.

Compositions according to the present invention are used as fungicides for controlling, preventing and/or treating phytopathogenic fungi in agricultural crops.

Disclosure of invention

This document reports stable, high-loading formulations comprising difenoconazole.

The disclosed formulations exhibit acceptable stability with respect to the maintenance of efficacy and potency of active ingredient and avoid unacceptable degradation of active substances to undesirable related substances.

The term “stable” as used herein refers to formulations containing less than 5% degradation products of active ingredient(s), as determined by HPLC analysis, under typical storage conditions, such as storage at 15°C for periods up to 24 months.

An analysis of the compositions of the present invention may be performed using other techniques known in the art.

The stability of the formulations of the present invention is demonstrated by the results below:

Initial difenoconazole content: 521.5 g/L

After storage for 2 weeks at 54°C, difenoconazole content: 518.7 g/L

After storage for 2 years at ambient temperature, difenoconazole content: 513.9 g/L.

This shows that formulations according to the present invention exhibit acceptable stability.

Claims (1)

Conclusions Conclusion 1. Composition comprising: (a) difenoconazole in an amount of 400 — 600 g/L, (b) one or more dispersants in an amount of 50 — 100 g/L, (c) thickeners in an amount of 0,1 — 50 g/L, (d) one or more agents selected from antifoams and/or biocides in an amount of 2 — 15 g/L, (e) water in an amount of 200 — 600 g/L. Claim 2. Composition according to claim 1 comprising: a) difenoconazole in an amount of 500 g/L, b) one or more dispersants in an amount of 50 - 100 g/L, c) one or more thickeners in an amount of 0.1 - 50 g/L, d) one or more agents selected from antifoams and/or biocides in an amount of 2 - 15 g/L, e) water in an amount of 400 - 500 g/L. Conclusion 3. Use of the compositions according to any of the preceding claims in controlling, preventing and/or treating phytopathogenic fungi in agricultural crops.