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AU8800598A - B7-binding molecules for treating immune diseases - Google Patents

B7-binding molecules for treating immune diseases

Info

Publication number
AU8800598A
AU8800598A AU88005/98A AU8800598A AU8800598A AU 8800598 A AU8800598 A AU 8800598A AU 88005/98 A AU88005/98 A AU 88005/98A AU 8800598 A AU8800598 A AU 8800598A AU 8800598 A AU8800598 A AU 8800598A
Authority
AU
Australia
Prior art keywords
binding molecules
immune diseases
treating immune
treating
diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU88005/98A
Inventor
Alfons Bosman
Marie-Ange Buyse
Katrien Lorre
Erwin Sablon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Innogenetics NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA
Publication of AU8800598A publication Critical patent/AU8800598A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70521CD28, CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AU88005/98A 1997-06-20 1998-06-22 B7-binding molecules for treating immune diseases Abandoned AU8800598A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97870092 1997-06-20
EP97870092 1997-06-20
PCT/EP1998/003791 WO1998058965A2 (en) 1997-06-20 1998-06-22 B7-binding molecules for treating immune diseases

Publications (1)

Publication Number Publication Date
AU8800598A true AU8800598A (en) 1999-01-04

Family

ID=8231013

Family Applications (1)

Application Number Title Priority Date Filing Date
AU88005/98A Abandoned AU8800598A (en) 1997-06-20 1998-06-22 B7-binding molecules for treating immune diseases

Country Status (4)

Country Link
EP (1) EP0988321A2 (en)
AU (1) AU8800598A (en)
CA (1) CA2292415A1 (en)
WO (1) WO1998058965A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001068132A1 (en) * 2000-03-14 2001-09-20 Genetics Institute, Inc. Use of a combination of agents that modulate b7 activity in inhibiting intestinal allograft rejection
WO2001068133A1 (en) * 2000-03-14 2001-09-20 Genetics Institute, Inc. Use of rapamycin and agents that inhibit b7 activity in immunomodulation
AU2001247401A1 (en) * 2000-03-14 2001-09-24 Genetics Institute Inc. Therapies that improve graft survival, using antibodies against a b7 antigen
MXPA02010011A (en) 2000-04-11 2003-04-25 Genentech Inc Multivalent antibodies and uses therefor.
JP2004500863A (en) 2000-06-06 2004-01-15 ブリストル−マイヤーズ スクイブ カンパニー B7-related nucleic acids and polypeptides useful for immunomodulation
US20030031675A1 (en) * 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
US7531168B2 (en) 2001-02-16 2009-05-12 Genetics Institute Llc Method for downmodulating immune response in type I diabetes
EP1423402A4 (en) * 2001-08-02 2006-07-05 Lilly Co Eli Novel polypeptide analogs and fusions and their methods of use
US20060002935A1 (en) 2002-06-28 2006-01-05 Domantis Limited Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor
US9321832B2 (en) 2002-06-28 2016-04-26 Domantis Limited Ligand
AU2005250216B2 (en) 2004-06-01 2009-12-10 Domantis Limited Bispecific fusion antibodies with enhanced serum half-life
US7563443B2 (en) 2004-09-17 2009-07-21 Domantis Limited Monovalent anti-CD40L antibody polypeptides and compositions thereof
KR20070084069A (en) 2004-10-08 2007-08-24 도만티스 리미티드 Single domain antibody against TENF1 and method of using the same
EP1841796A2 (en) 2004-12-02 2007-10-10 Domantis Limited Bispecific domain antibodies targeting serum albumin and glp-1 or pyy
GB0621513D0 (en) 2006-10-30 2006-12-06 Domantis Ltd Novel polypeptides and uses thereof
CN102159590A (en) 2008-07-18 2011-08-17 百时美施贵宝公司 CD28 binding monovalent compositions and methods of use
EA024877B1 (en) 2008-10-02 2016-10-31 Эмерджент Продакт Дивелопмент Сиэтл, Ллс Cd86 antagonist multi-target binding proteins
WO2014120916A1 (en) 2013-02-01 2014-08-07 Bristol-Myers Squibb Company Pegylated domain antibodies monovalent for cd28 binding and methods of use
IL254335B2 (en) * 2015-03-16 2023-04-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Isolated peptides derived from the b7 ligand dimer interface and uses thereof
EP3371208B8 (en) 2015-11-02 2024-10-23 Five Prime Therapeutics, Inc. Cd80 extracellular domain polypeptides and their use in cancer treatment
EP3515494A4 (en) 2016-09-26 2020-10-07 The Brigham and Women's Hospital, Inc. B-CELL-MEDIATED IMMUNSUPPRESSION REGULATORS
EA201992586A1 (en) 2017-04-28 2020-03-03 Файв Прайм Терапьютикс, Инк. METHODS FOR TREATING USING THE EXTRACELLULAR DOMAIN CD80 POLYPEPTIDES
CN110305220B (en) * 2018-03-27 2022-10-11 孙嘉琳 Cancer-targeted enhanced anti-tumor fusion protein and preparation method and application thereof
CN110305221B (en) * 2018-03-27 2022-10-11 孙嘉琳 Enhanced anti-tumor fusion protein, preparation method and application
JP2024537689A (en) * 2021-09-22 2024-10-16 ノーティラス・サブシディアリー・インコーポレイテッド Methods and systems for determining polypeptide interactions - Patents.com

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747034A (en) * 1992-07-09 1998-05-05 Chiron Corporation Methods and materials for the induction of T cell anergy
AU4158396A (en) * 1994-11-10 1996-06-06 Dana-Farber Cancer Institute Methods for inhibiting graft versus host disease in bone marrow transplantation
US6113898A (en) * 1995-06-07 2000-09-05 Idec Pharmaceuticals Corporation Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
EP0922111B1 (en) * 1996-07-23 2004-12-01 Tanox Pharma B.V. Induction of t cell tolerance using a soluble molecule that can simultaneously block two costimulatory pathways

Also Published As

Publication number Publication date
WO1998058965A2 (en) 1998-12-30
WO1998058965A3 (en) 1999-05-14
EP0988321A2 (en) 2000-03-29
CA2292415A1 (en) 1998-12-30

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase