[go: up one dir, main page]

AU8847798A - Semliki forest virus vectors for gene transfer into non-endothelial cardiovascular cells - Google Patents

Semliki forest virus vectors for gene transfer into non-endothelial cardiovascular cells

Info

Publication number
AU8847798A
AU8847798A AU88477/98A AU8847798A AU8847798A AU 8847798 A AU8847798 A AU 8847798A AU 88477/98 A AU88477/98 A AU 88477/98A AU 8847798 A AU8847798 A AU 8847798A AU 8847798 A AU8847798 A AU 8847798A
Authority
AU
Australia
Prior art keywords
endothelial
gene transfer
virus vectors
forest virus
semliki forest
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU88477/98A
Other languages
English (en)
Inventor
Yigal M. Pinto
Frens Pries
Anton J. M. Roks
Wiek H. Van Gilst
Jan Wilschut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inex Pharmaceuticals Corp
Original Assignee
Inex Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inex Pharmaceuticals Corp filed Critical Inex Pharmaceuticals Corp
Publication of AU8847798A publication Critical patent/AU8847798A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36141—Use of virus, viral particle or viral elements as a vector
    • C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU88477/98A 1997-08-15 1998-08-14 Semliki forest virus vectors for gene transfer into non-endothelial cardiovascular cells Abandoned AU8847798A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5593397P 1997-08-15 1997-08-15
US60055933 1997-08-15
US5611397P 1997-08-20 1997-08-20
US60056113 1997-08-20
PCT/CA1998/000784 WO1999009192A1 (fr) 1997-08-15 1998-08-14 Vecteurs tires du virus de la la foret du semliki pour le transfert de genes dans des cellules cardiovasculaires non endotheliales

Publications (1)

Publication Number Publication Date
AU8847798A true AU8847798A (en) 1999-03-08

Family

ID=26734773

Family Applications (1)

Application Number Title Priority Date Filing Date
AU88477/98A Abandoned AU8847798A (en) 1997-08-15 1998-08-14 Semliki forest virus vectors for gene transfer into non-endothelial cardiovascular cells

Country Status (3)

Country Link
EP (1) EP0996737A1 (fr)
AU (1) AU8847798A (fr)
WO (1) WO1999009192A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015686A (en) 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
US6451592B1 (en) 1996-04-05 2002-09-17 Chiron Corporation Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
US8647864B2 (en) 1999-04-14 2014-02-11 Novartis Ag Compositions and methods for generating an immune response utilizing alphavirus-based vector systems
EP1248653A2 (fr) * 2000-01-07 2002-10-16 Stichting Klinische Farmacologie Groningen Therapie genique visant a stimuler l'angiogenese et/ou le traitement de l'insuffisance cardiaque
CA2410948C (fr) 2000-05-31 2012-07-17 Chiron Corporation Procede de purification de particules de replicon des alphavirus
EP1802361B1 (fr) 2004-10-21 2009-11-18 Medtronic, Inc. Dispositif medical recouvert d'un polymere permettant l'elution d'angiotensine-(1-7) pour reduire la restenose et ameliorer la fonction cellulaire endotheliale

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646042A (en) * 1992-08-26 1997-07-08 Ribozyme Pharmaceuticals, Inc. C-myb targeted ribozymes
WO1996017072A2 (fr) * 1994-11-30 1996-06-06 Chiron Viagene, Inc. Vecteurs d'alphavirus de recombinaison
ES2301178T3 (es) * 1996-04-05 2008-06-16 Novartis Vaccines & Diagnostic Vectores basados en alfavirus recombinantes con inhibicion reducida de la sintesis macromolecular celular.

Also Published As

Publication number Publication date
WO1999009192A1 (fr) 1999-02-25
WO1999009192A9 (fr) 1999-05-06
EP0996737A1 (fr) 2000-05-03

Similar Documents

Publication Publication Date Title
AU4095999A (en) Cell cycle genes, proteins and uses thereof
AU1265197A (en) Target cell-specific vectors for inserting genes into cells, pharmaceuticals comprising such vectors and their use
EP1019028A4 (fr) PROTEINE DE $i(CHLAMYDIA), SEQUENCE GENIQUE, ET UTILISATIONS CORRESPONDANTES
AU6443298A (en) Self-assembling genes, vectors and uses thereof
AU6337698A (en) Fractional cell sorter
AU8828598A (en) Retrovirus and viral vectors
EP1025486A4 (fr) Architecture de multiplicateur regulier rapide
AU2678097A (en) Targeted viral vectors
AU3081899A (en) Viral vector directed to predetermined target cells
AU8836398A (en) Mass-mass cell gas centrifuge
EP1005561A4 (fr) Vecteurs et vecteurs viraux et lignees de cellules d'encapsidation les propageant
PL337942A1 (en) Isolated genes of dendricall cell membranic proteins
AU8368098A (en) Handling atm multicast cells
AU7476198A (en) Cell proliferation related genes
AU7042198A (en) Highly transparent, colour-pigmented high molecular weight material
AU6229098A (en) Cancer-associated genes
AU6229498A (en) Composition for gene introduction into cell
AU7962398A (en) Mammalian genes; related reagents
AU8847798A (en) Semliki forest virus vectors for gene transfer into non-endothelial cardiovascular cells
IL136679A0 (en) Grafted copolymers as gene carriers
AU8396198A (en) Axin gene and uses thereof
AU8382998A (en) P53 influenced gene expression
AU6537798A (en) Targeted cytolysis of cancer cells
AU4964097A (en) Novel semaphorin genes (i)
AU8999198A (en) Viral vector system capable of expressing an apoptosis-associated gene

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase