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AU7998794A - Nitrophenyl derivatives that can be activated by light - Google Patents

Nitrophenyl derivatives that can be activated by light

Info

Publication number
AU7998794A
AU7998794A AU79987/94A AU7998794A AU7998794A AU 7998794 A AU7998794 A AU 7998794A AU 79987/94 A AU79987/94 A AU 79987/94A AU 7998794 A AU7998794 A AU 7998794A AU 7998794 A AU7998794 A AU 7998794A
Authority
AU
Australia
Prior art keywords
activated
light
nitrophenyl derivatives
nitrophenyl
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU79987/94A
Inventor
Colin Henry Self
Stephen Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Newcastle University of Upon Tyne
Original Assignee
Newcastle University of Upon Tyne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newcastle University of Upon Tyne filed Critical Newcastle University of Upon Tyne
Publication of AU7998794A publication Critical patent/AU7998794A/en
Abandoned legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0042Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6891Pre-targeting systems involving an antibody for targeting specific cells
    • A61K47/6899Antibody-Directed Enzyme Prodrug Therapy [ADEPT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
AU79987/94A 1993-10-27 1994-10-26 Nitrophenyl derivatives that can be activated by light Abandoned AU7998794A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939322156A GB9322156D0 (en) 1993-10-27 1993-10-27 Activation of molecules
GB9322156 1993-10-27
PCT/GB1994/002359 WO1995011703A1 (en) 1993-10-27 1994-10-26 Nitrophenyl derivatives that can be activated by light

Publications (1)

Publication Number Publication Date
AU7998794A true AU7998794A (en) 1995-05-22

Family

ID=10744198

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79987/94A Abandoned AU7998794A (en) 1993-10-27 1994-10-26 Nitrophenyl derivatives that can be activated by light

Country Status (3)

Country Link
AU (1) AU7998794A (en)
GB (2) GB9322156D0 (en)
WO (1) WO1995011703A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0404187D0 (en) * 2004-02-25 2004-03-31 Biotransformations Ltd Binding agents
CA3128656A1 (en) 2007-08-22 2009-02-26 The Regents Of The University Of California Activatable binding polypeptides and methods of identification and use thereof
CN102482347B (en) 2009-01-12 2017-04-26 希托马克斯医疗有限责任公司 Modified antibody compositions and methods of making and using the same
RU2011138951A (en) 2009-02-23 2013-03-27 Сайтомкс Терапьютикс, Инк. PROTEINS AND WAYS OF THEIR APPLICATION
US10633453B2 (en) 2013-05-28 2020-04-28 Kaohsiung Medical University Antibody locker for the inactivation of protein drug
EA201991353A1 (en) 2016-12-09 2019-11-29 BIVALENT ANTIBODIES MASKED BY SPIRALIZED SPIRALS

Also Published As

Publication number Publication date
GB2298714A (en) 1996-09-11
WO1995011703A1 (en) 1995-05-04
GB9608530D0 (en) 1996-07-03
GB2298714B (en) 1998-01-28
GB9322156D0 (en) 1993-12-15

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