AU7209498A - Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist - Google Patents
Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonistInfo
- Publication number
- AU7209498A AU7209498A AU72094/98A AU7209498A AU7209498A AU 7209498 A AU7209498 A AU 7209498A AU 72094/98 A AU72094/98 A AU 72094/98A AU 7209498 A AU7209498 A AU 7209498A AU 7209498 A AU7209498 A AU 7209498A
- Authority
- AU
- Australia
- Prior art keywords
- quinoline
- antagonist
- carboxylic acid
- amino acids
- acid derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9706294 | 1997-03-26 | ||
| GBGB9706294.7A GB9706294D0 (en) | 1997-03-26 | 1997-03-26 | Heterocyclic compound |
| PCT/EP1998/001700 WO1998042673A1 (en) | 1997-03-26 | 1998-03-24 | Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7209498A true AU7209498A (en) | 1998-10-20 |
| AU731394B2 AU731394B2 (en) | 2001-03-29 |
Family
ID=10809909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU72094/98A Ceased AU731394B2 (en) | 1997-03-26 | 1998-03-24 | Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0971896A1 (en) |
| JP (1) | JP2001518901A (en) |
| KR (1) | KR20010005567A (en) |
| CN (1) | CN1257482A (en) |
| AP (1) | AP9901659A0 (en) |
| AU (1) | AU731394B2 (en) |
| BR (1) | BR9808424A (en) |
| CA (1) | CA2284710A1 (en) |
| EA (1) | EA199900755A1 (en) |
| GB (1) | GB9706294D0 (en) |
| HU (1) | HUP0001661A3 (en) |
| ID (1) | ID24306A (en) |
| IL (1) | IL131919A0 (en) |
| IS (1) | IS5186A (en) |
| NO (1) | NO994679L (en) |
| NZ (1) | NZ337793A (en) |
| PL (1) | PL335865A1 (en) |
| TR (1) | TR199902315T2 (en) |
| WO (1) | WO1998042673A1 (en) |
| YU (1) | YU47699A (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9917822D0 (en) * | 1999-07-29 | 1999-09-29 | Imperial College | Nmda antagonist |
| DE10132725A1 (en) | 2001-07-05 | 2006-08-03 | Grünenthal GmbH | Substituted γ-lactone compounds |
| DE10137487A1 (en) * | 2001-08-03 | 2003-03-27 | Gruenenthal Gmbh | Substituted 5,6,6a, 11b-tetrahydro-7-oxa-6-aza-benzo [c] fluorene-6-carboxylic acid derivatives |
| DE10306202A1 (en) * | 2003-02-13 | 2004-08-26 | Grünenthal GmbH | 2-(hetero)aryl-2-(N-((hetero)aryl)-amino)-acetic acid derivatives useful e.g. for treating anxiety, inflammation, allergy, depression, diarrhea or especially pain is NMDA antagonist |
| JP4360891B2 (en) | 2003-12-09 | 2009-11-11 | アルパイン株式会社 | Electronic device having broadcast receiving function and display method of electronic program guide in the device |
| NZ565080A (en) | 2005-07-22 | 2011-03-31 | Mochida Pharm Co Ltd | Novel heterocyclidene acetamide derivative |
| RU2451014C2 (en) * | 2005-07-22 | 2012-05-20 | Мотида Фармасьютикал Ко., Лтд. | Novel heterocyclidene acetamide derivative |
| US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| KR102609676B1 (en) | 2017-06-12 | 2023-12-05 | 글리테크 엘엘씨. | Treatment of depression with NMDA antagonists and D2/5HT2A or selective 5HT2A antagonists |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69029668T2 (en) * | 1989-03-08 | 1997-08-07 | Merck Sharp & Dohme | Tetrahydroquinoline derivatives, useful for neurodegenerative diseases |
| PL186781B1 (en) * | 1995-09-29 | 2004-02-27 | Glaxo Wellcome Spa | Tetraguinolines as nmda antagonists |
| GB9617305D0 (en) * | 1996-08-17 | 1996-09-25 | Glaxo Wellcome Spa | Heterocyclic compounds |
-
1997
- 1997-03-26 GB GBGB9706294.7A patent/GB9706294D0/en active Pending
-
1998
- 1998-03-24 EP EP98919133A patent/EP0971896A1/en not_active Withdrawn
- 1998-03-24 CN CN98805302A patent/CN1257482A/en active Pending
- 1998-03-24 AU AU72094/98A patent/AU731394B2/en not_active Ceased
- 1998-03-24 IL IL13191998A patent/IL131919A0/en unknown
- 1998-03-24 CA CA002284710A patent/CA2284710A1/en not_active Abandoned
- 1998-03-24 HU HU0001661A patent/HUP0001661A3/en unknown
- 1998-03-24 YU YU47699A patent/YU47699A/en unknown
- 1998-03-24 BR BR9808424-0A patent/BR9808424A/en not_active IP Right Cessation
- 1998-03-24 TR TR1999/02315T patent/TR199902315T2/en unknown
- 1998-03-24 WO PCT/EP1998/001700 patent/WO1998042673A1/en not_active Ceased
- 1998-03-24 NZ NZ337793A patent/NZ337793A/en unknown
- 1998-03-24 EA EA199900755A patent/EA199900755A1/en unknown
- 1998-03-24 AP APAP/P/1999/001659A patent/AP9901659A0/en unknown
- 1998-03-24 ID IDW991108A patent/ID24306A/en unknown
- 1998-03-24 JP JP54323498A patent/JP2001518901A/en active Pending
- 1998-03-24 PL PL98335865A patent/PL335865A1/en unknown
- 1998-03-24 KR KR1019997008630A patent/KR20010005567A/en not_active Withdrawn
-
1999
- 1999-09-17 IS IS5186A patent/IS5186A/en unknown
- 1999-09-24 NO NO994679A patent/NO994679L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1257482A (en) | 2000-06-21 |
| YU47699A (en) | 2001-12-26 |
| PL335865A1 (en) | 2000-05-22 |
| NO994679L (en) | 1999-11-24 |
| AP9901659A0 (en) | 1999-09-30 |
| BR9808424A (en) | 2000-05-23 |
| WO1998042673A1 (en) | 1998-10-01 |
| GB9706294D0 (en) | 1997-05-14 |
| TR199902315T2 (en) | 2000-05-22 |
| NO994679D0 (en) | 1999-09-24 |
| HUP0001661A2 (en) | 2000-09-28 |
| ID24306A (en) | 2000-07-13 |
| JP2001518901A (en) | 2001-10-16 |
| CA2284710A1 (en) | 1998-10-01 |
| NZ337793A (en) | 2001-02-23 |
| EA199900755A1 (en) | 2000-08-28 |
| IL131919A0 (en) | 2001-03-19 |
| HUP0001661A3 (en) | 2001-12-28 |
| IS5186A (en) | 1999-09-17 |
| EP0971896A1 (en) | 2000-01-19 |
| KR20010005567A (en) | 2001-01-15 |
| AU731394B2 (en) | 2001-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |