AU7102594A - Oligonucleotides which inhibit hiv protease function - Google Patents

Oligonucleotides which inhibit hiv protease function

Info

Publication number: AU7102594A
Authority: AU; Australia
Prior art keywords: oligonucleotides; hiv protease; inhibit hiv; protease function; function
Prior art date: 1993-06-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU71025/94A

Inventor

Bruce A Beutel

George R Coppola

Michael I. Sherman

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pharmagenics Inc

Original Assignee

Pharmagenics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-09

Filing date

1994-06-09

Publication date

1995-01-03

1994-06-09 Application filed by Pharmagenics Inc filed Critical Pharmagenics Inc

1995-01-03 Publication of AU7102594A publication Critical patent/AU7102594A/en

Status Abandoned legal-status Critical Current

Links

108091034117 Oligonucleotide Proteins 0.000 title 1
108091005804 Peptidases Proteins 0.000 title 1
239000004365 Protease Substances 0.000 title 1
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AU71025/94A 1993-06-09 1994-06-09 Oligonucleotides which inhibit hiv protease function Abandoned AU7102594A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US7387393A	1993-06-09	1993-06-09
US073873		1993-06-09
PCT/US1994/006456 WO1994029479A1 (en)	1993-06-09	1994-06-09	Oligonucleotides which inhibit hiv protease function

Publications (1)

Publication Number	Publication Date
AU7102594A true AU7102594A (en)	1995-01-03

Family

ID=22116321

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU71025/94A Abandoned AU7102594A (en)	1993-06-09	1994-06-09	Oligonucleotides which inhibit hiv protease function

Country Status (2)

Country	Link
AU (1)	AU7102594A (en)
WO (1)	WO1994029479A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6465188B1 (en)	1990-06-11	2002-10-15	Gilead Sciences, Inc.	Nucleic acid ligand complexes
US6011020A (en) *	1990-06-11	2000-01-04	Nexstar Pharmaceuticals, Inc.	Nucleic acid ligand complexes
US6147204A (en) *	1990-06-11	2000-11-14	Nexstar Pharmaceuticals, Inc.	Nucleic acid ligand complexes
US6168778B1 (en)	1990-06-11	2001-01-02	Nexstar Pharmaceuticals, Inc.	Vascular endothelial growth factor (VEGF) Nucleic Acid Ligand Complexes
EP1564290B1 (en) *	1995-05-03	2008-07-16	Gilead Sciences, Inc.	Method for identifying nucleic acid ligands of tissue targets
US5859228A (en) *	1995-05-04	1999-01-12	Nexstar Pharmaceuticals, Inc.	Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
US8071737B2 (en)	1995-05-04	2011-12-06	Glead Sciences, Inc.	Nucleic acid ligand complexes
US6229002B1 (en)	1995-06-07	2001-05-08	Nexstar Pharmaceuticlas, Inc.	Platelet derived growth factor (PDGF) nucleic acid ligand complexes
US6426335B1 (en)	1997-10-17	2002-07-30	Gilead Sciences, Inc.	Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
US6051698A (en) *	1997-06-06	2000-04-18	Janjic; Nebojsa	Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
US8853376B2 (en)	2002-11-21	2014-10-07	Archemix Llc	Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
WO2023220087A1 (en) *	2022-05-10	2023-11-16	Amylyx Pharmaceuticals, Inc.	Oligonucleotide compositions and methods thereof

1994
- 1994-06-09 AU AU71025/94A patent/AU7102594A/en not_active Abandoned
- 1994-06-09 WO PCT/US1994/006456 patent/WO1994029479A1/en not_active Ceased

Also Published As

Publication number	Publication date
WO1994029479A1 (en)	1994-12-22

Publication	Publication Date	Title
NZ329626A (en)	1999-08-30	1-phenylthio-2-benzamido-3-hydroxy-4-piperidino-butane, hiv protease inhibitors
AU7583794A (en)	1995-05-11	1-amino-ethylindole-derivatives
AU6001594A (en)	1994-08-29	Imidazoazines
AU6710294A (en)	1994-11-08	Tetrahydro-beta-carbolines
AU6705294A (en)	1994-11-08	Tetrahydro-pyrido-indole
AU7102594A (en)	1995-01-03	Oligonucleotides which inhibit hiv protease function
AU7131991A (en)	1991-08-29	Hiv protease inhibiting agents
AU5314794A (en)	1994-08-18	New pseudopeptides having an antiviral action
AUPM982594A0 (en)	1995-01-05	HIV protease inhibitors
AU5798394A (en)	1994-10-06	Thiadiazinones
AU6259294A (en)	1994-10-11	Life-savingfloat
AU6828894A (en)	1994-12-12	Hiv protease inhibitors
AU1035495A (en)	1995-06-13	Improved polymerase
AU6389494A (en)	1994-10-11	Tv-projector
AU8104694A (en)	1995-05-29	Bagbottle
AU6971594A (en)	1995-01-03	Cyclobutylazoles
AU6427194A (en)	1994-10-24	Aza-androstane-17beta -carboxamides
AU7285994A (en)	1995-03-23	Suncap
AU5780894A (en)	1994-09-22	Crankhead
AU6726594A (en)	1994-12-20	Tee-box
AU6327994A (en)	1994-11-24	Bridging member
AU7194594A (en)	1995-02-28	7alpha-amino-1,1-dioxocefem l-valylamides
AU674745B2 (en)	1997-01-09	Eco-brick
AU6312794A (en)	1994-11-24	Pallets
HK1008334A (en)	1999-05-07	Hiv protease inhibitors