AU637049B2 - Recombinant flagellin vaccines - Google Patents

Recombinant flagellin vaccines Download PDF

Info

Publication number: AU637049B2
Authority: AU; Australia
Prior art keywords: recombinant; flagellin; epitope; gene; protein
Prior art date: 1988-05-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

AU36979/89A

Other languages

English (en)

Other versions

AU3697989A (en

Inventor

William Robert Marjarian

Salete Maria Cardozo Newton

Bruce Arnold Dunbar Stocker

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wyeth Holdings LLC

Leland Stanford Junior University

Original Assignee

Praxis Biologics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-05-05

Filing date

1989-05-05

Publication date

1993-05-20

1989-05-05 Application filed by Praxis Biologics Inc filed Critical Praxis Biologics Inc

1989-11-29 Publication of AU3697989A publication Critical patent/AU3697989A/en

1993-05-20 Application granted granted Critical

1993-05-20 Publication of AU637049B2 publication Critical patent/AU637049B2/en

1995-10-26 Assigned to AMERICAN CYANAMID COMPANY, BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIVERSITY, THE reassignment AMERICAN CYANAMID COMPANY Alteration of Name(s) in Register under S187 Assignors: BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIVERSITY, THE, PRAXIS BIOLOGICS, INC.

2009-05-05 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Zoology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Tropical Medicine & Parasitology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AU36979/89A 1988-05-05 1989-05-05 Recombinant flagellin vaccines Ceased AU637049B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US190570		1980-09-25
US19057088A	1988-05-05	1988-05-05

Publications (2)

Publication Number	Publication Date
AU3697989A AU3697989A (en)	1989-11-29
AU637049B2 true AU637049B2 (en)	1993-05-20

Family

ID=22701885

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU36979/89A Ceased AU637049B2 (en)	1988-05-05	1989-05-05	Recombinant flagellin vaccines

Country Status (10)

Country	Link
EP (1)	EP0419513B1 (fr)
JP (1)	JP2793673B2 (fr)
AT (1)	ATE121782T1 (fr)
AU (1)	AU637049B2 (fr)
CA (1)	CA1340817C (fr)
DE (1)	DE68922394T2 (fr)
DK (1)	DK263390A (fr)
FI (1)	FI104638B (fr)
NO (1)	NO302031B1 (fr)
WO (1)	WO1989010967A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU660945B2 (en) *	1990-10-01	1995-07-13	Minister for Agriculture, Fisheries and Food in Her Britannic Majesty's Government of The United Kingdom of Great Britain and Northern Ireland, The	Salmonella polynucleotide sequence

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5712088A (en) *	1987-11-18	1998-01-27	Chiron Corporation	Methods for detecting Hepatitis C virus using polynucleotides specific for same
US5714596A (en) *	1987-11-18	1998-02-03	Chiron Corporation	NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus
US6171782B1 (en)	1987-11-18	2001-01-09	Chiron Corporation	Antibody compositions to HCV and uses thereof
US5698390A (en) *	1987-11-18	1997-12-16	Chiron Corporation	Hepatitis C immunoassays
US6861212B1 (en)	1987-11-18	2005-03-01	Chiron Corporation	NANBV diagnostics and vaccines
US7118757B1 (en)	1988-12-19	2006-10-10	Wyeth Holdings Corporation	Meningococcal class 1 outer-membrane protein vaccine
JP3436756B2 (ja) *	1988-12-19	2003-08-18	アメリカン・サイアナミド・カンパニー	髄膜炎菌のクラスｉの外膜タンパク質のワクチン
US6027729A (en) *	1989-04-20	2000-02-22	Chiron Corporation	NANBV Diagnostics and vaccines
ATE190656T1 (de) *	1990-10-01	2000-04-15	Mini Agriculture & Fisheries	Verfahren zur prüfung für salmonella
GB9101550D0 (en) *	1991-01-24	1991-03-06	Mastico Robert A	Antigen-presenting chimaeric protein
IL101639A0 (en) *	1992-04-17	1992-12-30	Yeda Res & Dev	Recombinant influenza vaccines
DE60011560T2 (de) *	1999-12-28	2005-08-18	Akzo Nobel N.V.	Salmonella Impfstoff, der keinen Antikörper gegen Flagellin oder gegen Flagella induziert
JPWO2004055045A1 (ja) *	2002-12-16	2006-04-20	株式会社シーエーエフラボラトリーズ	サルモネラ抗原処方物、それを使用した抗体検査キット及びサブユニットワクチン
US20080248068A1 (en)	2004-05-07	2008-10-09	Hans-Gustaf Ljunggren	Use of Flagellin as an Adjuvant for Vaccine
JP2008521431A (ja) *	2004-12-02	2008-06-26	シーエスアイアール	破壊されたフラゲリン遺伝子を含むグラム陽性細菌細胞、フラゲリンベースの融合タンパク質及び金属イオンの液体からの除去における使用
CA2589556A1 (fr)	2004-12-16	2006-08-03	Wake Forest University Health Sciences	Utilisation de flagelline en immunotherapie antitumorale
AU2006206647C1 (en)	2005-01-19	2011-01-20	Vaxinnate Corporation	Compositions comprising pathogen-associated molecular patterns and antigens and their use to stimulate an immune response
EP2476432B1 (fr)	2006-03-07	2015-08-19	Vaxinnate Corporation	Compositions incluant de l'hémagglutinine, procédés pour leur fabrication et leurs méthodes d'utilisation
WO2009128951A2 (fr)	2008-04-18	2009-10-22	Vaxinnate Corporation	Compositions de protéines du virus respiratoire syncytial et leurs méthodes d'utilisation
US8932598B2 (en)	2012-08-28	2015-01-13	Vaxinnate Corporation	Fusion proteins and methods of use
CN102816246B (zh) *	2012-09-04	2014-07-23	成都蓉生药业有限责任公司	一种人巨细胞病毒免疫原融合蛋白及其制备方法和用途
WO2016046357A1 (fr)	2014-09-26	2016-03-31	Bavarian Nordic A/S	Procédés et compositions pour l'immunisation intra-nasale avec un mva recombinant codant pour une flagelline
EP3221464B1 (fr) *	2014-11-18	2022-02-23	The Trustees of Columbia University in the City of New York	Détection d'analytes à l'aide de cellules vivantes
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1989
- 1989-05-05 AT AT89906507T patent/ATE121782T1/de not_active IP Right Cessation
- 1989-05-05 EP EP89906507A patent/EP0419513B1/fr not_active Expired - Lifetime
- 1989-05-05 DE DE68922394T patent/DE68922394T2/de not_active Expired - Fee Related
- 1989-05-05 CA CA000598847A patent/CA1340817C/fr not_active Expired - Fee Related
- 1989-05-05 AU AU36979/89A patent/AU637049B2/en not_active Ceased
- 1989-05-05 WO PCT/US1989/001932 patent/WO1989010967A1/fr not_active Ceased
- 1989-05-05 JP JP1505981A patent/JP2793673B2/ja not_active Expired - Fee Related
1990
- 1990-11-02 FI FI905441A patent/FI104638B/fi not_active IP Right Cessation
- 1990-11-02 DK DK263390A patent/DK263390A/da not_active Application Discontinuation
- 1990-11-05 NO NO904806A patent/NO302031B1/no not_active IP Right Cessation

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* Cited by examiner, † Cited by third party
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AU660945B2 (en) *	1990-10-01	1995-07-13	Minister for Agriculture, Fisheries and Food in Her Britannic Majesty's Government of The United Kingdom of Great Britain and Northern Ireland, The	Salmonella polynucleotide sequence

Also Published As

Publication number	Publication date
EP0419513B1 (fr)	1995-04-26
CA1340817C (fr)	1999-11-09
WO1989010967A1 (fr)	1989-11-16
ATE121782T1 (de)	1995-05-15
DK263390D0 (da)	1990-11-02
DE68922394D1 (de)	1995-06-01
DE68922394T2 (de)	1995-10-05
NO904806D0 (no)	1990-11-05
FI104638B (fi)	2000-03-15
NO904806L (no)	1991-01-03
JPH04502402A (ja)	1992-05-07
AU3697989A (en)	1989-11-29
FI905441A0 (fi)	1990-11-02
DK263390A (da)	1991-01-04
NO302031B1 (no)	1998-01-12
EP0419513A1 (fr)	1991-04-03
JP2793673B2 (ja)	1998-09-03

Publication	Publication Date	Title
US6130082A (en)	2000-10-10	Recombinant flagellin vaccines
AU637049B2 (en)	1993-05-20	Recombinant flagellin vaccines
US5112749A (en)	1992-05-12	Vaccines for the malaria circumsporozoite protein
EP0652962B1 (fr)	1998-12-16	Expression de proteines recombinantes fusionnees dans des bacteries attenuees
Wu et al.	1989	Expression of immunogenic epitopes of hepatitis B surface antigen with hybrid flagellin proteins by a vaccine strain of Salmonella.
JP5566684B2 (ja)	2014-08-06	Ｃｌｏｓｔｒｉｄｉｕｍｄｉｆｆｉｃｉｌｅに対する、組換え毒素Ａ／毒素Ｂワクチン
EP0672116B1 (fr)	2003-06-04	Mutants de deletion utilises en tant que vaccins contre le cholera
Olive et al.	2003	Potential of lipid core peptide technology as a novel self-adjuvanting vaccine delivery system for multiple different synthetic peptide immunogens
US5708155A (en)	1998-01-13	Enhanced immunogenicity using leukotoxin chimeras
Barry et al.	1996	Expression and immunogenicity of pertussis toxin S1 subunit-tetanus toxin fragment C fusions in Salmonella typhi vaccine strain CVD 908
CN101180312A (zh)	2008-05-14	来自尿路病原性大肠杆菌的免疫原
US5422110A (en)	1995-06-06	Enhanced immunogenicity using leukotoxin chimeras
WO1992005192A1 (fr)	1992-04-02	Epitopes des lymphocytes t
US6096320A (en)	2000-08-01	Vaccines with chimeric protein comprising gamma-interferon and leukotoxin derived from pasteurella haemolytica
LeClerc et al.	1990	Induction of virus-neutralizing antibodies by bacteria expressing the C3 poliovirus epitope in the periplasm. The route of immunization influences the isotypic distribution and the biologic activity of the antipoliovirus antibodies.
Stocker	1990	Aromatic-dependent Salmonella as live vaccine presenters of foreign epitopes as inserts in flagellin
Schmidt et al.	1988	Synthetic peptides corresponding to protective epitopes of Escherichia coli digalactoside-binding pilin prevent infection in a murine pyelonephritis model.
US5273889A (en)	1993-12-28	Gamma-iterferon-leukotoxin gene fusions and uses thereof
US5874088A (en)	1999-02-23	Deletion mutants of cholera vaccines expressing heterologous antigens
US7235245B2 (en)	2007-06-26	Chimeric lyssavirus nucleic acids and polypeptides
Alves et al.	1998	Epitope specificity of antibodies raised against enterotoxigenic Escherichia coli CFA/I fimbriae in mice immunized with naked DNA
US6797272B1 (en)	2004-09-28	Enhanced immunogenicity using leukotoxin chimeras
AU617402B2 (en)	1991-11-28	Vaccines for malaria
Makoff et al.	2020	Recombinant Antigens as Components of a Diphtheria-Tetanys-PerSüssis Vaccine
WO1994006911A2 (fr)	1994-03-31	Antigenes de mycoplasma pulmonis, et procedes et compositions destines a etre utilises dans le clonage et la vaccination

AU637049B2 - Recombinant flagellin vaccines - Google Patents

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