AU6152000A - Copolymers for the transfer of nucleic acids to the cell - Google Patents
Copolymers for the transfer of nucleic acids to the cellInfo
- Publication number
- AU6152000A AU6152000A AU61520/00A AU6152000A AU6152000A AU 6152000 A AU6152000 A AU 6152000A AU 61520/00 A AU61520/00 A AU 61520/00A AU 6152000 A AU6152000 A AU 6152000A AU 6152000 A AU6152000 A AU 6152000A
- Authority
- AU
- Australia
- Prior art keywords
- copolymers
- cell
- transfer
- nucleic acids
- nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229920001577 copolymer Polymers 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
- A61K47/6929—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
- A61K47/6931—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer
- A61K47/6935—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer the polymer being obtained otherwise than by reactions involving carbon to carbon unsaturated bonds, e.g. polyesters, polyamides or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33396—Polymers modified by chemical after-treatment with organic compounds containing nitrogen having oxygen in addition to nitrogen
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Nanotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99112260A EP1063254A1 (en) | 1999-06-25 | 1999-06-25 | Copolymers for the transport of nucleic acids in the cell |
| EP99112260 | 1999-06-25 | ||
| PCT/EP2000/005869 WO2001000709A1 (en) | 1999-06-25 | 2000-06-23 | Copolymers for the transfer of nucleic acids to the cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU6152000A true AU6152000A (en) | 2001-01-31 |
Family
ID=8238431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU61520/00A Abandoned AU6152000A (en) | 1999-06-25 | 2000-06-23 | Copolymers for the transfer of nucleic acids to the cell |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP1063254A1 (en) |
| JP (1) | JP2003503569A (en) |
| AU (1) | AU6152000A (en) |
| CA (1) | CA2377211A1 (en) |
| MX (1) | MXPA01012802A (en) |
| WO (1) | WO2001000709A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003300380B2 (en) | 2002-12-30 | 2008-11-06 | Nektar Therapeutics | Multi-arm polypeptide-poly(ethylene glycol) block copolymers as drug delivery vehicles |
| JP4535229B2 (en) | 2003-05-08 | 2010-09-01 | 国立大学法人 東京大学 | Polyethylene glycol-polycation block copolymer |
| JP2005080598A (en) * | 2003-09-10 | 2005-03-31 | Japan Science & Technology Agency | Method for introducing plasmid DNA using β-1,3-glucan derivative |
| JPWO2005078084A1 (en) * | 2004-02-13 | 2008-01-10 | 株式会社東京大学Tlo | Polyion complex carrying double-stranded oligonucleic acid, process for producing the same and pharmaceutical composition containing the same |
| JP4870941B2 (en) * | 2005-05-09 | 2012-02-08 | 公立大学法人大阪府立大学 | High molecular compound |
| DE102005023993A1 (en) * | 2005-05-20 | 2006-11-23 | TransMIT Gesellschaft für Technologietransfer mbH | Non-viral vector system for the transport of nucleic acid into the lung |
| EP1979407B1 (en) * | 2006-01-19 | 2014-08-06 | Allexcel, Inc. | Solubilization and targeted delivery of drugs with self-assembling amphiphilic polymers |
| CN101636169B (en) * | 2007-01-22 | 2014-05-07 | 阿列克斯塞尔公司 | Self-assembling amphiphilic polymers as antiviral agents |
| KR101470679B1 (en) * | 2007-07-19 | 2014-12-08 | 올엑셀, 인크. | Self-assembling amphiphilic polymers as anticancer agents |
| CN111727049A (en) | 2017-12-07 | 2020-09-29 | 阿道恰公司 | An injectable solution at pH 7 comprising at least one basal insulin with a PI between 5.8 and 8.5 and a copolyamino acid with a carboxylate charge and a hydrophobic group |
| TW201938190A (en) | 2017-12-07 | 2019-10-01 | 法商阿道洽公司 | Injectable solution at PH 7 comprising at least one basal insulin wherein the PI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5219564A (en) * | 1990-07-06 | 1993-06-15 | Enzon, Inc. | Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon |
| CA2146990A1 (en) * | 1992-10-14 | 1994-04-28 | Robert A. Snow | Chelating polymers |
| AU4690596A (en) * | 1994-12-30 | 1996-07-24 | Chiron Viagene, Inc. | Nucleic acid condensing agents with reduced immunogenicity |
| GB9600272D0 (en) * | 1996-01-06 | 1996-03-06 | Univ Nottingham | Polymers |
| JP3808938B2 (en) * | 1996-07-16 | 2006-08-16 | 久光製薬株式会社 | Nucleic acid carrier |
| GB9623051D0 (en) * | 1996-11-06 | 1997-01-08 | Schacht Etienne H | Delivery of DNA to target cells in biological systems |
| KR20010071279A (en) * | 1998-05-20 | 2001-07-28 | 추후제출 | A hepatocyte targeting polyethylene glyco-grafted poly-l-lysine polymeric gene carrier |
-
1999
- 1999-06-25 EP EP99112260A patent/EP1063254A1/en not_active Withdrawn
-
2000
- 2000-06-23 CA CA002377211A patent/CA2377211A1/en not_active Abandoned
- 2000-06-23 MX MXPA01012802A patent/MXPA01012802A/en unknown
- 2000-06-23 AU AU61520/00A patent/AU6152000A/en not_active Abandoned
- 2000-06-23 JP JP2001506716A patent/JP2003503569A/en active Pending
- 2000-06-23 WO PCT/EP2000/005869 patent/WO2001000709A1/en not_active Ceased
- 2000-06-23 EP EP00947874A patent/EP1208133A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2377211A1 (en) | 2001-01-04 |
| JP2003503569A (en) | 2003-01-28 |
| MXPA01012802A (en) | 2003-06-24 |
| WO2001000709A1 (en) | 2001-01-04 |
| EP1208133A1 (en) | 2002-05-29 |
| EP1063254A1 (en) | 2000-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |