AU3718595A - Transduction of genes into human hematopoietic stem cells using recombinant adeno-associated viral vectors - Google Patents
Transduction of genes into human hematopoietic stem cells using recombinant adeno-associated viral vectorsInfo
- Publication number
- AU3718595A AU3718595A AU37185/95A AU3718595A AU3718595A AU 3718595 A AU3718595 A AU 3718595A AU 37185/95 A AU37185/95 A AU 37185/95A AU 3718595 A AU3718595 A AU 3718595A AU 3718595 A AU3718595 A AU 3718595A
- Authority
- AU
- Australia
- Prior art keywords
- transduction
- genes
- stem cells
- viral vectors
- hematopoietic stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30798094A | 1994-09-16 | 1994-09-16 | |
| US307980 | 1994-09-16 | ||
| PCT/US1995/011858 WO1996008560A1 (en) | 1994-09-16 | 1995-09-18 | Transduction of genes into human hematopoietic stem cells using recombinant adeno-associated viral vectors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU3718595A true AU3718595A (en) | 1996-03-29 |
Family
ID=23192009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU37185/95A Abandoned AU3718595A (en) | 1994-09-16 | 1995-09-18 | Transduction of genes into human hematopoietic stem cells using recombinant adeno-associated viral vectors |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU3718595A (en) |
| WO (1) | WO1996008560A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998024924A1 (en) * | 1996-12-05 | 1998-06-11 | Introgene B.V. | Genetic modification of primate hemopoietic repopulating stem cells |
| US6919209B1 (en) | 1998-12-04 | 2005-07-19 | City Of Hope | Method of genetically modifying very primitive quiescent human hematopoietic stem cells |
| AU2036700A (en) * | 1998-12-04 | 2000-06-26 | City Of Hope | A method of genetically modifying very primitive quiescent human hematopoietic stem cells |
| US10610606B2 (en) | 2018-02-01 | 2020-04-07 | Homology Medicines, Inc. | Adeno-associated virus compositions for PAH gene transfer and methods of use thereof |
| WO2019152843A1 (en) | 2018-02-01 | 2019-08-08 | Homology Medicines, Inc. | Adeno-associated virus compositions for restoring pah gene function and methods of use thereof |
| US11306329B2 (en) | 2018-02-19 | 2022-04-19 | City Of Hope | Adeno-associated virus compositions for restoring F8 gene function and methods of use thereof |
| TW202140791A (en) | 2020-01-13 | 2021-11-01 | 美商霍蒙拉奇醫藥公司 | Methods of treating phenylketonuria |
| TW202208632A (en) | 2020-05-27 | 2022-03-01 | 美商同源醫藥公司 | Adeno-associated virus compositions for restoring pah gene function and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5225834A (en) * | 1975-08-20 | 1977-02-26 | Hitachi Cable Ltd | Adhesive |
| JPS6092379A (en) * | 1983-10-27 | 1985-05-23 | Daiabondo Kogyo Kk | Hot-melt sealing agent composition for headlamp |
| US4851462A (en) * | 1988-01-21 | 1989-07-25 | Uniroyal Plastics Company, Inc. | Adhesive for bonding cured EPDM rubber containing a crosslinked halogenated butyl rubber |
| JPH06116539A (en) * | 1991-10-01 | 1994-04-26 | Shoei Kagaku Kogyo Kk | Water-based adhesive for polyolefin foam |
-
1995
- 1995-09-18 WO PCT/US1995/011858 patent/WO1996008560A1/en not_active Ceased
- 1995-09-18 AU AU37185/95A patent/AU3718595A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996008560A1 (en) | 1996-03-21 |
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