[go: up one dir, main page]

AU3198200A - Prrsv vaccines - Google Patents

Prrsv vaccines

Info

Publication number
AU3198200A
AU3198200A AU31982/00A AU3198200A AU3198200A AU 3198200 A AU3198200 A AU 3198200A AU 31982/00 A AU31982/00 A AU 31982/00A AU 3198200 A AU3198200 A AU 3198200A AU 3198200 A AU3198200 A AU 3198200A
Authority
AU
Australia
Prior art keywords
prrsv vaccines
prrsv
vaccines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU31982/00A
Inventor
Helene Groot-Bramel Verheije
Janneke Meulenberg
Helene Verheije
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ID Lelystad Instituut voor Dierhouderij en Diergezondheid BV
Original Assignee
ID Lelystad Instituut voor Dierhouderij en Diergezondheid BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ID Lelystad Instituut voor Dierhouderij en Diergezondheid BV filed Critical ID Lelystad Instituut voor Dierhouderij en Diergezondheid BV
Publication of AU3198200A publication Critical patent/AU3198200A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10041Use of virus, viral particle or viral elements as a vector
    • C12N2770/10043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10061Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU31982/00A 1999-03-08 2000-03-08 Prrsv vaccines Abandoned AU3198200A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99200668 1999-03-08
EP99200668 1999-03-08
PCT/NL2000/000152 WO2000053787A1 (en) 1999-03-08 2000-03-08 Prrsv vaccines

Publications (1)

Publication Number Publication Date
AU3198200A true AU3198200A (en) 2000-09-28

Family

ID=8239954

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31982/00A Abandoned AU3198200A (en) 1999-03-08 2000-03-08 Prrsv vaccines

Country Status (7)

Country Link
US (2) US20030049274A1 (en)
EP (1) EP1157121B1 (en)
JP (1) JP3961222B2 (en)
AU (1) AU3198200A (en)
CA (1) CA2366072C (en)
PL (1) PL204373B1 (en)
WO (1) WO2000053787A1 (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
JP3961222B2 (en) 1999-03-08 2007-08-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー PRRSV vaccine
CA2370372C (en) 1999-04-22 2009-02-24 United States Department Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
WO2002095040A1 (en) * 2001-05-21 2002-11-28 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Delections in arterivirus replicons
ATE380529T1 (en) * 1999-10-22 2007-12-15 Archus Orthopedics Inc FACET ARTHROPLASTY DEVICES
EP1156111A1 (en) * 2000-05-19 2001-11-21 Stichting Dienst Landbouwkundig Onderzoek Chimeric arterivirus-like particles
PL370541A1 (en) * 2001-03-09 2005-05-30 Boehringer Ingelheim Vetmedica Gmbh Live attenuated strains of prrs virus
US7595054B2 (en) * 2003-06-09 2009-09-29 Healthbanks Biotech Co., Ltd. Fusion antigen used as vaccine
US8206950B2 (en) * 2003-06-09 2012-06-26 Animal Technology Institute Taiwan Fusion antigen used as vaccine and method of making them
RU2007101725A (en) 2004-06-18 2008-07-27 Риджентс Оф Дзе Юниверсити Оф Миннесота (Us) IDENTIFICATION OF VIRUS-INFECTED AND VIRUS-VACCINATED ORGANISMS
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
JP4320357B2 (en) * 2005-02-25 2009-08-26 ファイザー・プロダクツ・インク N protein variant of porcine genital respiratory syndrome virus
US7449296B2 (en) 2005-02-28 2008-11-11 Mj Biologics, Inc. Method and kit for detecting porcine reproductive and respiratory syndrome virus
CA2894069C (en) 2005-06-24 2019-02-26 Regents Of The University Of Minnesota Prrs viruses, infectious clones, mutants thereof, and methods of use
US7608272B2 (en) * 2005-08-30 2009-10-27 Board Of Regents Of The University Of Nebraska Methods and compositions for vaccination of animals with PRRSV antigens with improved immunogenicity
US7666585B2 (en) * 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
JP2010531143A (en) * 2007-06-25 2010-09-24 サウス ダコタ ステート ユニバーシティー Recombinant North American type 1 porcine genital respiratory syndrome virus and method of use
US20090246226A1 (en) * 2008-03-28 2009-10-01 Zeon Corporation Avian vaccines possessing a positive marker gene
CN102316895A (en) * 2008-08-25 2012-01-11 贝林格尔.英格海姆维特梅迪卡有限公司 Vaccine against highly pathogenic porcine reproductive and respiratory syndrome (HP PRRS)
CN101748125B (en) * 2008-12-11 2012-05-30 中国科学院动物研究所 siRNA fragment and application thereof for treating and/or preventing porcine reproductive and respiratory syndrome
TWI627281B (en) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 Methods of reducing viricidal activity in pcv-2 compositions and pcv-2 compositions with an improved immunogenicity
CA2800824A1 (en) 2010-06-02 2011-12-08 Virginia Tech Intellectual Properties, Inc. Novel modified live-attenuated vaccines (mlv) and subunit vaccines created by dna shuffling against porcine reproductive and respiratory syndrome virus (prrsv)
PH12017500962B1 (en) 2011-02-17 2023-02-22 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
EP2675476B1 (en) 2011-02-17 2015-09-16 Boehringer Ingelheim Vetmedica GmbH Commercial scale process for production of prrsv
WO2012166493A1 (en) * 2011-06-01 2012-12-06 Merial Limited Needle-free administration of prrsv vaccines
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
EP2737058A1 (en) 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
CN103087996B (en) * 2013-01-18 2014-07-16 中国农业大学 Recombinant porcine reproductive and respiratory syndrome virus as well as preparation method and application thereof
CN105073130A (en) 2013-03-15 2015-11-18 勃林格殷格翰动物保健公司 Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
AU2014369774B2 (en) 2013-12-20 2020-11-26 Boehringer Ingelheim Vetmedica Gmbh PRRS virus variant, European PRRS virus cDNA clone, and uses thereof
CN104991061B (en) * 2015-06-12 2017-04-12 中国农业科学院哈尔滨兽医研究所 Peste des petits ruminant virus antibody detection kit based on IPMA
US10279031B2 (en) 2016-05-11 2019-05-07 Phibro Animal Health Corporation Composition comprising antigens and a mucosal adjuvant and a method for using
CN111748530B (en) * 2020-07-20 2023-08-15 河南省农业科学院 Method for improving in-vitro culture infection amount of porcine reproductive and respiratory syndrome virus and application thereof
CN114395583B (en) * 2021-11-01 2024-03-29 扬州大学 cDNA clone of porcine reproductive and respiratory syndrome virus for expressing secretion type luciferase, construction method and application thereof
CN115025212B (en) * 2022-06-20 2025-08-01 天康制药股份有限公司 MRNA vaccine for preventing porcine reproductive and respiratory syndrome and preparation method thereof
CN118791578B (en) * 2024-07-29 2024-12-27 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) Antigen epitope of nsp12 protein of porcine reproductive and respiratory syndrome virus, monoclonal antibody and application

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3137631A (en) * 1959-12-01 1964-06-16 Faberge Inc Encapsulation in natural products
US3080291A (en) * 1960-06-10 1963-03-05 Jensen Salsberg Lab Inc Serial passage of distemper virus in tissue cultures of chick embryo and canine tissue and vaccine therefrom
US3959457A (en) * 1970-06-05 1976-05-25 Temple University Microparticulate material and method of making such material
US4015100A (en) * 1974-01-07 1977-03-29 Avco Everett Research Laboratory, Inc. Surface modification
US4122167A (en) * 1977-02-09 1978-10-24 Merck & Co., Inc. Respiratory synctial vaccine
US4205060A (en) * 1978-12-20 1980-05-27 Pennwalt Corporation Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use
US4224412A (en) * 1979-05-01 1980-09-23 Dorofeev Viktor M Living virus culture vaccine against canine distemper and method of preparing same
US4554159A (en) * 1981-11-12 1985-11-19 Institute Merieux Vaccine and method of immunizing against herpes simplex virus (types 1 and 2)
US4452747A (en) * 1982-03-22 1984-06-05 Klaus Gersonde Method of and arrangement for producing lipid vesicles
US4468346A (en) * 1983-10-27 1984-08-28 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies to porcine immunoglobulins
DE3405100A1 (en) * 1984-02-14 1985-08-14 Drägerwerk AG, 2400 Lübeck PT CATALYST ON A CARRIER AS AN AIR PURIFIER
US4744933A (en) * 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
US5008050A (en) * 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
US4921706A (en) * 1984-11-20 1990-05-01 Massachusetts Institute Of Technology Unilamellar lipid vesicles and method for their formation
US4606940A (en) * 1984-12-21 1986-08-19 The Ohio State University Research Foundation Small particle formation and encapsulation
US5206163A (en) * 1985-07-08 1993-04-27 Chiron Corporation DNA encoding bovine diarrhea virus protein
US4753884A (en) * 1986-01-28 1988-06-28 Novagene, Inc. Pseudorabies virus mutants, vaccines containing same, methods for the production of same and methods for the use of same
FR2602791B1 (en) * 1986-08-18 1988-11-10 Ministere Agri Direction Quali METHOD FOR CULTURING TURKEY INFECTIOUS RHINOTRACHEITIS VIRUS, AND VACCINE PREPARED FROM THE VIRUS OBTAINED THEREBY
NZ222465A (en) 1986-11-07 1992-11-25 Pasteur Institut Nanb (non a, non b hepatitis viral) antigen
US5009956A (en) * 1987-02-24 1991-04-23 Univ Minnesota Phospholipase A2-resistant liposomes
DE3833925A1 (en) 1988-03-11 1989-09-21 Inst Angewandte Biotechnologie PROCESS AND MANUFACTURE OF VIRUS AND VIRAL ANTIGEN AND DEVICE THEREFOR
US5213759A (en) * 1988-05-05 1993-05-25 Elopak Systems A.G. Sterilization
US4927637A (en) * 1989-01-17 1990-05-22 Liposome Technology, Inc. Liposome extrusion method
US4944948A (en) * 1989-02-24 1990-07-31 Liposome Technology, Inc. EGF/Liposome gel composition and method
US5132117A (en) * 1990-01-11 1992-07-21 Temple University Aqueous core microcapsules and method for their preparation
AU7007491A (en) 1990-02-02 1991-08-08 Schweiz. Serum- & Impfinstitut Bern Cdna corresponding to the genome of negative-strand rna viruses, and process for the production of infectious negative-strand rna viruses
AU2196592A (en) * 1991-06-06 1993-01-08 Stichting Centraal Diergeneeskundig Instituut Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
MX9204885A (en) 1991-08-26 1994-05-31 Boehringer Animal Health Inc VACCINE COMPOSITION INCLUDING VIRUSES OF INFERTILITY AND RESPIRATORY SYNDROME OF PIGS.
US6080570A (en) * 1991-08-26 2000-06-27 Boehringer Ingelheim Vetmedica, Inc. Method of producing a vaccine for Swine Infertility and Respiratory Syndrome
US5846805A (en) * 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
DE601062T1 (en) * 1991-08-26 1995-05-18 David Allen Benfield VACCINE AGAINST AND DIAGNOSTIC METHOD FOR THE PIG INFERTILITY AND BREATHING SYNDROME (SUAS).
US6982160B2 (en) * 1991-08-26 2006-01-03 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions that include SIRS virus
WO1993006211A1 (en) 1991-09-16 1993-04-01 Collins James E Vaccine for mystery swine disease and method for diagnosis thereof
WO1993007898A1 (en) 1991-10-14 1993-04-29 Akzo Nobel N.V. Porcine reproductive respiratory syndrome vaccine and diagnostic
FR2686097B1 (en) * 1992-01-14 1994-12-30 Rhone Merieux PREPARATION OF ANTIGENS AND MYSTERY DISEASE VIRUS VACCINES, ANTIGENS AND VACCINES OBTAINED FOR THE PREVENTION OF THIS DISEASE.
US5338543A (en) * 1992-02-27 1994-08-16 Ambico, Inc. Thimerosal inactivated mycoplasma hyopneumoniae vaccine
TW289731B (en) * 1992-07-09 1996-11-01 Akzo Nv
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6251397B1 (en) * 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US5419907A (en) * 1992-11-10 1995-05-30 Iowa State University Research Foundation, Inc. Pathogenic porcine respiratory coronavirus
JP3710095B2 (en) * 1993-02-08 2005-10-26 バイエル・コーポレーシヨン Method for propagating porcine reproductive and respiratory syndrome virus and its use in vaccines
ES2074950B1 (en) 1993-09-17 1996-03-16 Iberica Cyanamid VACCINE FOR THE PREVENTION OF REPRODUCTIVE AND RESPIRATORY DISEASE OF THE SOW.
EP0659885A1 (en) * 1993-12-21 1995-06-28 Akzo Nobel N.V. Vaccine against viruses associated with antibody-dependent-enhancement of viral infectivity
DE4407489A1 (en) * 1994-03-07 1995-09-14 Bayer Ag Vaccine for the prevention of respiratory and reproductive diseases of the pig
EP0676467B1 (en) * 1994-04-11 2001-10-04 Akzo Nobel N.V. European vaccine strains of the porcine reproductive respiratory syndrome virus (PRRSV)
WO1995028227A1 (en) 1994-04-15 1995-10-26 Temple University Aqueous solvent encapsulation method, apparatus and microcapsules
GB2289279B (en) 1994-05-13 1998-09-16 Iberica Cyanamid Diagnostic kits and vaccines containing recombinant PRRSV proteins
CA2196555C (en) * 1994-08-05 2012-07-03 Michael P. Murtaugh Vr-2332 viral nucleotide sequence and methods of use
ES2223058T3 (en) 1995-03-14 2005-02-16 Akzo Nobel N.V. EXPRESSION IN THE SAME POLYPEPTIDE CELL OF THE VIRUS REPRODUCTIVE AND RESPIRATORY SYNDROME.
US5690940A (en) * 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof
ES2102971B1 (en) 1996-01-25 1998-03-01 Hipra Lab Sa NEW ATTENUATED STRAIN OF THE VIRUS CAUSING THE RESPIRATORY AND REPRODUCTIVE SYNDROME (PRRS), THE VACCINES AND DIAGNOSTIC MEDIA OBTAINABLE WITH THE SAME AND THE PROCEDURES FOR ITS OBTAINING.
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
SK119498A3 (en) 1996-03-01 1999-07-12 Schering Corp Porcine reproductive and respiratory syndrome vaccine
US6015663A (en) * 1996-03-01 2000-01-18 The United States Of America As Represented By The Secretary Of Agriculture Restriction enzyme screen for differentiating porcine reproductive and respiratory syndrome virus strains
US5976537A (en) * 1996-07-02 1999-11-02 The United States Of America As Represented By The Secretary Of Agriculture Porcine reproductive and respiratory syndrome vaccine
DK0835930T3 (en) * 1996-10-09 2001-06-18 Akzo Nobel Nv European vaccine strains of porcine reproductive and respiratory syndrome virus. (PRRSV)
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
WO1998035023A1 (en) 1997-02-07 1998-08-13 Origen, Inc. Method for growing porcine reproductive and respiratory syndrome virus for use as vaccines and diagnostic assays
ATE365746T1 (en) * 1997-05-06 2007-07-15 Boehringer Ingelheim Vetmed PRRSV ANTIGENS BASED ON PEPTIDE SEQUENCES OF THE PRRS VIRUS FOR USE AS VACCINES AND FOR DIAGNOSTIC TESTS
WO1998055626A2 (en) * 1997-06-05 1998-12-10 Origen, Inc. Recombinant porcine reproductive and respiratory syndrome virus (prrsv) for use as a vaccine
US7211379B2 (en) * 1997-10-03 2007-05-01 Merial Sas Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2
US6391314B1 (en) * 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
NZ501264A (en) * 1998-12-22 2001-09-28 Pfizer Prod Inc Polynucleotide DNA sequence encoding an infectious RNA molecule encoding a North American PRRS
US7132106B2 (en) * 1998-12-22 2006-11-07 Pfizer Inc. Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
US7618797B2 (en) 1998-12-22 2009-11-17 Pfizer Inc Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
US7691389B2 (en) 1998-12-22 2010-04-06 Pfizer Inc Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
FR2789695B1 (en) * 1999-02-11 2003-03-07 Merial Sas VIRAL VACCINES AND VACCINES BASED ON RECOMBINANT AND REPLICATIVE SWINE ADENOVIRUSES
JP3961222B2 (en) 1999-03-08 2007-08-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー PRRSV vaccine
CA2370372C (en) 1999-04-22 2009-02-24 United States Department Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
US20040213805A1 (en) * 1999-10-12 2004-10-28 Verheije Monique Helene Deletions in arterivirus replicons
WO2002095040A1 (en) 2001-05-21 2002-11-28 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Delections in arterivirus replicons
US20020012670A1 (en) * 2000-01-26 2002-01-31 Knut Elbers Recombinant attenuation of porcine reproductive and respiratory syndrome (PRRSV)
DK1255815T3 (en) 2000-02-08 2006-10-30 Univ Minnesota Porcine reproductive and respiratory syndrome virus for methods of use
EP1156111A1 (en) * 2000-05-19 2001-11-21 Stichting Dienst Landbouwkundig Onderzoek Chimeric arterivirus-like particles
US7018638B2 (en) * 2000-12-19 2006-03-28 Wyeth Mycoplasma hyopneumoniae bacterin vaccine
US7279166B2 (en) * 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US6841364B2 (en) 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
ATE557082T1 (en) * 2002-04-05 2012-05-15 Boehringer Ingelheim Vetmed SEQUENCE POSITIONS FOR ADJUSTMENT IN PRRSV
US7335361B2 (en) 2003-06-09 2008-02-26 Animal Technology Institute Taiwan Fusion antigen used as vaccine
US7722878B2 (en) 2004-06-17 2010-05-25 Boehringer Ingelheim Vetmedica, Inc. PRRSV subunit vaccines
RU2007101725A (en) 2004-06-18 2008-07-27 Риджентс Оф Дзе Юниверсити Оф Миннесота (Us) IDENTIFICATION OF VIRUS-INFECTED AND VIRUS-VACCINATED ORGANISMS
US20060063151A1 (en) * 2004-09-21 2006-03-23 Michael Roof Porcine reproductive and respiratory syndrome isolates and methods of use
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
EP1838343B1 (en) 2005-01-13 2010-03-31 Boehringer Ingelheim Vetmedica Gmbh Prrs vaccines
CN106075422B (en) 2005-11-29 2021-05-28 衣阿华州立大学研究基金公司 Identification and use of protective antigenic determinants of porcine reproductive and respiratory syndrome virus (PRRSV)
WO2008109237A2 (en) 2007-02-13 2008-09-12 Washington State University Research Foundation Macrophage cell-lines for propagation of porcine reproductive and respiratory syndrome virus
WO2008121958A1 (en) 2007-04-02 2008-10-09 Boehringer Ingelheim Vetmedica, Inc. Use of prrsv vaccines to reduce pcv2 viremia
US20100003278A1 (en) 2008-07-03 2010-01-07 Boehringer Ingelheim Vetmedica, Inc. Immunological Compositions Effective for Lessening the Severity or Incidence of PRRSV Signs and Methods of Use Thereof
CN102316895A (en) 2008-08-25 2012-01-11 贝林格尔.英格海姆维特梅迪卡有限公司 Vaccine against highly pathogenic porcine reproductive and respiratory syndrome (HP PRRS)
US20100129398A1 (en) 2008-11-26 2010-05-27 Boehringer Ingelheim Vetmedica, Inc. Materials and Methods for Control of Porcine Reproductive and Respiratory Syndrome
DK2558118T3 (en) 2010-04-16 2019-08-26 Univ Gent ANIMAL PROTECTIVE VACCINE AGAINST PIG REProduction and Respiratory Syndrome Virus
US8728487B2 (en) 2011-01-20 2014-05-20 Hua Wu Attenuated live vaccine for prevention of porcine reproductive and respiratory syndrome

Also Published As

Publication number Publication date
CA2366072A1 (en) 2000-09-14
WO2000053787A9 (en) 2012-04-26
US8790656B2 (en) 2014-07-29
EP1157121B1 (en) 2013-04-24
US20030049274A1 (en) 2003-03-13
JP2002537845A (en) 2002-11-12
WO2000053787A1 (en) 2000-09-14
JP3961222B2 (en) 2007-08-22
EP1157121A1 (en) 2001-11-28
PL351486A1 (en) 2003-04-22
US20060240041A1 (en) 2006-10-26
CA2366072C (en) 2007-07-10
PL204373B1 (en) 2010-01-29

Similar Documents

Publication Publication Date Title
AU3198200A (en) Prrsv vaccines
AU1173201A (en) Skin-gripper
AU3092999A (en) Digital-timeshare-exchange
AU6600300A (en) Pneumococcal vaccines
AU4115400A (en) Short-circuiter
AU6335000A (en) Depthimeter
AU5977700A (en) Vaccines
AU2023701A (en) Sketcher
AU2699800A (en) Organoceramics
AU2804600A (en) Arylaminoalkylamides
AU6098300A (en) Follistatin-3
AU6158700A (en) Vaccine
AU5811600A (en) Vaccine
AU1901801A (en) Glucofuranoses
AU3809500A (en) Expression
AU1915601A (en) Periotome
AU7303400A (en) Osseo-distractor
AU2582200A (en) Windturbine
AU7788600A (en) Colon-tumour-associated antigens
AU2197301A (en) Microlamp
AU5084300A (en) New vaccine formulations - 1
AU1737601A (en) Collectalbum
AU4935700A (en) New vaccine formulations-3
AU4351900A (en) Inducible vaccines
AU3174800A (en) Dartboards

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase