AU2123288A - Renin inhibiting peptides with nonpeptide linkages - Google Patents
Renin inhibiting peptides with nonpeptide linkagesInfo
- Publication number
- AU2123288A AU2123288A AU21232/88A AU2123288A AU2123288A AU 2123288 A AU2123288 A AU 2123288A AU 21232/88 A AU21232/88 A AU 21232/88A AU 2123288 A AU2123288 A AU 2123288A AU 2123288 A AU2123288 A AU 2123288A
- Authority
- AU
- Australia
- Prior art keywords
- nonpeptide
- linkages
- inhibiting peptides
- renin inhibiting
- renin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102100028255 Renin Human genes 0.000 title 1
- 108090000783 Renin Proteins 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8361487A | 1987-08-07 | 1987-08-07 | |
| US083614 | 1987-08-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2123288A true AU2123288A (en) | 1989-03-09 |
Family
ID=22179523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU21232/88A Abandoned AU2123288A (en) | 1987-08-07 | 1988-07-11 | Renin inhibiting peptides with nonpeptide linkages |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0364493A1 (en) |
| JP (1) | JPH02504509A (en) |
| AU (1) | AU2123288A (en) |
| WO (1) | WO1989001488A1 (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990003389A1 (en) * | 1988-09-26 | 1990-04-05 | The Upjohn Company | Renin inhibitory peptides containing maleamide substituents |
| PL335484A1 (en) | 1997-02-26 | 2000-04-25 | Pfizer | Derivatives of heteroarylhexamide, their production and application as selective inhibitors of mip-1a being assimilated by its ccr1 receptor |
| ES2275675T3 (en) | 2000-03-23 | 2007-06-16 | Elan Pharmaceuticals, Inc. | COMPOUNDS AND METHODS TO TREAT ALZHEIMER'S DISEASE. |
| US6846813B2 (en) | 2000-06-30 | 2005-01-25 | Pharmacia & Upjohn Company | Compounds to treat alzheimer's disease |
| EP1666452A2 (en) | 2000-06-30 | 2006-06-07 | Elan Pharmaceuticals, Inc. | Compounds to treat Alzheimer's disease |
| ES2252257T3 (en) | 2000-06-30 | 2006-05-16 | Elan Pharmaceuticals, Inc. | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE. |
| PE20020276A1 (en) | 2000-06-30 | 2002-04-06 | Elan Pharm Inc | SUBSTITUTE AMINE COMPOUNDS AS ß-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER |
| CA2452039A1 (en) | 2001-06-27 | 2003-01-09 | Elan Pharmaceuticals, Inc. | Beta-hydroxyamine derivatives useful in treatment of alzheimer's disease |
| KR100787131B1 (en) * | 2006-07-04 | 2007-12-21 | 한국생명공학연구원 | Compounds that inhibit HIF-1 activity, preparation method thereof, and pharmaceutical composition containing the same as an active ingredient |
| US11136295B2 (en) * | 2018-10-29 | 2021-10-05 | Kempharm, Inc. | D-amphetamine compounds, compositions, and processes for making and using the same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3418491A1 (en) * | 1984-05-18 | 1985-11-21 | Merck Patent Gmbh, 6100 Darmstadt | DIAMINO ACID DERIVATIVES |
| FI88400C (en) * | 1984-08-06 | 1993-05-10 | Upjohn Co | FRAMEWORK FOR THE FRAME STATION INHIBITION OF PEPTIDER |
| US4665055A (en) * | 1985-06-17 | 1987-05-12 | Merck & Co., Inc. | Peptide renin inhibitors |
| DE3538749A1 (en) * | 1985-10-31 | 1987-05-07 | Merck Patent Gmbh | PEPTIDE |
| FI870474A7 (en) * | 1986-02-07 | 1987-08-08 | Ciba Geigy Ag | MED SVAVELHALTIGA GRUPER SUBSTITUERADE 5-AMINO-4-HYDROXIVALERYL DERIVATIVES. |
-
1988
- 1988-07-11 AU AU21232/88A patent/AU2123288A/en not_active Abandoned
- 1988-07-11 EP EP88906552A patent/EP0364493A1/en not_active Withdrawn
- 1988-07-11 WO PCT/US1988/002255 patent/WO1989001488A1/en not_active Ceased
- 1988-07-11 JP JP88506281A patent/JPH02504509A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02504509A (en) | 1990-12-20 |
| WO1989001488A1 (en) | 1989-02-23 |
| EP0364493A1 (en) | 1990-04-25 |
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