AU2005269599A1 - Implantable device having reservoir with controlled release of medication and method of manufacturing the same - Google Patents
Implantable device having reservoir with controlled release of medication and method of manufacturing the same Download PDFInfo
- Publication number
- AU2005269599A1 AU2005269599A1 AU2005269599A AU2005269599A AU2005269599A1 AU 2005269599 A1 AU2005269599 A1 AU 2005269599A1 AU 2005269599 A AU2005269599 A AU 2005269599A AU 2005269599 A AU2005269599 A AU 2005269599A AU 2005269599 A1 AU2005269599 A1 AU 2005269599A1
- Authority
- AU
- Australia
- Prior art keywords
- medication
- reservoir
- head
- tip
- providing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000003814 drug Substances 0.000 title claims description 106
- 229940079593 drug Drugs 0.000 title claims description 105
- 238000004519 manufacturing process Methods 0.000 title claims description 14
- 238000013270 controlled release Methods 0.000 title description 2
- 239000000463 material Substances 0.000 claims description 49
- 238000000034 method Methods 0.000 claims description 18
- 238000003780 insertion Methods 0.000 claims description 16
- 230000037431 insertion Effects 0.000 claims description 16
- 230000035699 permeability Effects 0.000 claims description 15
- 241000083513 Punctum Species 0.000 claims description 12
- 241000124008 Mammalia Species 0.000 claims description 11
- 229920001296 polysiloxane Polymers 0.000 claims description 10
- 238000000465 moulding Methods 0.000 claims description 8
- 238000004873 anchoring Methods 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims 5
- 210000003128 head Anatomy 0.000 description 19
- 239000011148 porous material Substances 0.000 description 12
- 239000003889 eye drop Substances 0.000 description 8
- 239000006196 drop Substances 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 229940012356 eye drops Drugs 0.000 description 4
- 238000002483 medication Methods 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 210000004087 cornea Anatomy 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 230000000144 pharmacologic effect Effects 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 238000011200 topical administration Methods 0.000 description 3
- 238000013461 design Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- 206010006784 Burning sensation Diseases 0.000 description 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 description 1
- 206010013774 Dry eye Diseases 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000003477 cochlea Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000003500 cycloplegic effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000004452 decreased vision Effects 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 210000003027 ear inner Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002911 mydriatic effect Effects 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- 210000004083 nasolacrimal duct Anatomy 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00772—Apparatus for restoration of tear ducts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0023—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in porosity
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Ophthalmology & Optometry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Plastic & Reconstructive Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Prostheses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/899,416 | 2004-07-26 | ||
| US10/899,417 | 2004-07-26 | ||
| US10/899,417 US20060020253A1 (en) | 2004-07-26 | 2004-07-26 | Implantable device having reservoir with controlled release of medication and method of manufacturing the same |
| US10/899,416 US7117870B2 (en) | 2004-07-26 | 2004-07-26 | Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same |
| PCT/US2005/025998 WO2006014793A1 (fr) | 2004-07-26 | 2005-07-21 | Dispositif implantable comprenant un reservoir a liberation commandee de medicament et procede de fabrication de celui-ci |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2005269599A1 true AU2005269599A1 (en) | 2006-02-09 |
Family
ID=35787435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005269599A Abandoned AU2005269599A1 (en) | 2004-07-26 | 2005-07-21 | Implantable device having reservoir with controlled release of medication and method of manufacturing the same |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1778198A1 (fr) |
| AU (1) | AU2005269599A1 (fr) |
| CA (1) | CA2573892A1 (fr) |
| WO (1) | WO2006014793A1 (fr) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101052435B (zh) | 2004-07-02 | 2010-12-08 | Qlt塞子传递公司 | 治疗介质递送装置 |
| US8246569B1 (en) | 2004-08-17 | 2012-08-21 | California Institute Of Technology | Implantable intraocular pressure drain |
| EP1998829B1 (fr) | 2006-03-14 | 2011-02-09 | University Of Southern California | Dispositif Mems et procede de livraison d'agents therapeutiques |
| ES2640458T3 (es) | 2006-03-31 | 2017-11-03 | Mati Therapeutics Inc. | Implantes del sistema de drenaje nasolagrimal para terapia medicamentosa |
| US9474645B2 (en) * | 2006-06-21 | 2016-10-25 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
| BRPI0713719A2 (pt) * | 2006-06-21 | 2012-10-30 | Johnson & Johnson Vision Care | plugues punctais para a entrega de agentes ativos |
| US9173773B2 (en) * | 2006-06-21 | 2015-11-03 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
| SG138567A1 (en) * | 2006-06-21 | 2008-01-28 | Johnson & Johnson Vision Care | Punctal plugs for the delivery of active agents |
| NZ598483A (en) | 2007-09-07 | 2013-08-30 | Quadra Logic Tech Inc | Drug cores for sustained release of therapeutic agents |
| EP3372205A1 (fr) | 2007-09-07 | 2018-09-12 | Mati Therapeutics Inc. | Détection d'un implant lacrymal |
| US9308124B2 (en) | 2007-12-20 | 2016-04-12 | University Of Southern California | Apparatus and methods for delivering therapeutic agents |
| US20090192493A1 (en) | 2008-01-03 | 2009-07-30 | University Of Southern California | Implantable drug-delivery devices, and apparatus and methods for refilling the devices |
| US9849238B2 (en) | 2008-05-08 | 2017-12-26 | Minipumps, Llc | Drug-delivery pump with intelligent control |
| CN102202708B (zh) | 2008-05-08 | 2015-01-21 | 迷你泵有限责任公司 | 药物输送泵及其制造方法 |
| EP2898911A1 (fr) | 2008-05-08 | 2015-07-29 | MiniPumps, LLC | Pompes implantables et canules à cet effet |
| CN102202706A (zh) | 2008-05-08 | 2011-09-28 | 迷你泵有限责任公司 | 可植入药物传送装置与用于填充该装置的设备和方法 |
| USD629503S1 (en) | 2009-05-08 | 2010-12-21 | Sean Caffey | Implantable drug-delivery pump |
| CN102576385B (zh) | 2009-08-18 | 2016-02-24 | 迷你泵有限责任公司 | 具有自适应控制的电解药物输送泵 |
| US8808257B2 (en) | 2009-08-31 | 2014-08-19 | Johnson & Johnson Vision Care, Inc. | Methods and apparatus for pulsatile release of medicaments from a punctal plug |
| CA2781629A1 (fr) * | 2009-11-27 | 2011-06-03 | Sascha K. Zarins | Implants lacrimaux contenant un noyau de medicament fendu et inserable |
| US10286146B2 (en) | 2011-03-14 | 2019-05-14 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
| US9919099B2 (en) | 2011-03-14 | 2018-03-20 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
| US9603997B2 (en) | 2011-03-14 | 2017-03-28 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
| DK3290024T3 (da) | 2011-08-29 | 2019-06-03 | Mati Therapeutics Inc | Vedvarende indgivelse af aktive midler til behandling af glaukom og okulær hypertension |
| US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
| WO2018217662A1 (fr) * | 2017-05-22 | 2018-11-29 | California Institute Of Technology | Dispositif de transport de petite molécule doté d'une charge anti-condensation pour administration de médicament ou élimination de déchet |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3993071A (en) * | 1971-09-09 | 1976-11-23 | Alza Corporation | Bioerodible ocular device |
| US5378475A (en) * | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
| US6196993B1 (en) * | 1998-04-20 | 2001-03-06 | Eyelab Group, Llc | Ophthalmic insert and method for sustained release of medication to the eye |
-
2005
- 2005-07-21 WO PCT/US2005/025998 patent/WO2006014793A1/fr not_active Ceased
- 2005-07-21 AU AU2005269599A patent/AU2005269599A1/en not_active Abandoned
- 2005-07-21 CA CA002573892A patent/CA2573892A1/fr not_active Abandoned
- 2005-07-21 EP EP05773660A patent/EP1778198A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006014793A1 (fr) | 2006-02-09 |
| EP1778198A1 (fr) | 2007-05-02 |
| CA2573892A1 (fr) | 2006-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |