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AU2004269361B2 - Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells - Google Patents

Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells Download PDF

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Publication number
AU2004269361B2
AU2004269361B2 AU2004269361A AU2004269361A AU2004269361B2 AU 2004269361 B2 AU2004269361 B2 AU 2004269361B2 AU 2004269361 A AU2004269361 A AU 2004269361A AU 2004269361 A AU2004269361 A AU 2004269361A AU 2004269361 B2 AU2004269361 B2 AU 2004269361B2
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cells
neurons
population
neural
cell
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AU2004269361A1 (en
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Xue-Jun Li
Su-Chun Zhang
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Wisconsin Alumni Research Foundation
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
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    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00Drugs for disorders of the nervous system
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    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
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    • C12N2500/24Iron; Fe chelators; Transferrin
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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AU2004269361A 2003-08-29 2004-08-27 Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells Expired AU2004269361B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US49883103P 2003-08-29 2003-08-29
US60/498,831 2003-08-29
US49957003P 2003-09-02 2003-09-02
US60/499,570 2003-09-02
PCT/US2004/027841 WO2005021720A2 (fr) 2003-08-29 2004-08-27 Procede de differentiation in vitro de cellules souches neuronales, de neurones moteurs et de neurones de dopamine provenant de cellules souches embryonnaires de primates

Publications (2)

Publication Number Publication Date
AU2004269361A1 AU2004269361A1 (en) 2005-03-10
AU2004269361B2 true AU2004269361B2 (en) 2010-05-20

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AU2004269361A Expired AU2004269361B2 (en) 2003-08-29 2004-08-27 Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells

Country Status (8)

Country Link
EP (1) EP1670901A4 (fr)
JP (2) JP2007503811A (fr)
KR (2) KR20080109943A (fr)
AU (1) AU2004269361B2 (fr)
CA (1) CA2536588C (fr)
GB (1) GB2421029B (fr)
IL (2) IL173832A (fr)
WO (1) WO2005021720A2 (fr)

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US8153424B2 (en) 2001-10-03 2012-04-10 Wisconsin Alumni Research Foundation Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells
US7588937B2 (en) 2001-10-03 2009-09-15 Wisconsin Alumni Research Foundation Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells
US7632679B2 (en) * 2002-07-16 2009-12-15 The Trustees Of Columbia University In The City Of New York Systems and methods for screening for modulators of neural differentiation
JP4792290B2 (ja) * 2005-12-27 2011-10-12 財団法人 東京都医学総合研究所 神経幹細胞の製造方法
EA027648B9 (ru) 2006-03-07 2018-01-31 Гита Шроф КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ЭМБРИОНАЛЬНЫЕ СТВОЛОВЫЕ КЛЕТКИ ЧЕЛОВЕКА (ЭСКч) ИЛИ КЛЕТКИ-ПРОИЗВОДНЫЕ ЭСКч, И ИХ ПРИМЕНЕНИЕ
KR100838013B1 (ko) * 2006-06-07 2008-06-12 제일약품주식회사 인간배아줄기세포로부터 단계적 선별법을 통해 고수율로신경전구세포, 신경세포 및 기능성 도파민신경세포를생성하는 방법
CA2721952C (fr) 2008-04-22 2019-11-12 Regenerative Research Foundation Cellules souches de l'epithelium pigmentaire retinien
KR101168053B1 (ko) * 2009-11-06 2012-07-24 연세대학교 산학협력단 효율적이고 보편적인 전분화능 줄기세포의 신경세포 분화 유도방법
CN103052707A (zh) 2010-07-30 2013-04-17 剑桥实业有限公司 人类多能细胞的皮层生成
US9487752B2 (en) 2011-03-30 2016-11-08 Cellular Dynamics International, Inc. Priming of pluripotent stem cells for neural differentiation
JP6015112B2 (ja) * 2012-05-11 2016-10-26 株式会社ニコン 細胞評価装置、細胞評価方法およびプログラム
MA67580B1 (fr) * 2015-11-12 2024-09-30 F. Hoffmann-La Roche Ag Oligonucléotides pour induire l'expression de paternal ube3a
WO2017123806A1 (fr) 2016-01-12 2017-07-20 Cedars-Sinai Medical Center Procédé de suivi non destructeur de processus biologiques dans des systèmes de culture de tissu microfluidiques
WO2017136479A1 (fr) 2016-02-01 2017-08-10 Cedars-Sinai Medical Center Systèmes et procédés de mise en croissance de cellules intestinales dans des dispositifs microfluidiques
JPWO2017209290A1 (ja) * 2016-06-03 2019-04-11 国立大学法人京都大学 多能性幹細胞由来運動ニューロンの製造及びその用途
JP6376196B2 (ja) * 2016-09-29 2018-08-22 株式会社ニコン 細胞評価装置、細胞評価方法およびプログラム
WO2018140647A1 (fr) 2017-01-25 2018-08-02 Cedars-Sinai Medical Center Induction in vitro de différenciation de type mammaire à partir de cellules souches pluripotentes humaines
US11767513B2 (en) 2017-03-14 2023-09-26 Cedars-Sinai Medical Center Neuromuscular junction
WO2018176001A2 (fr) 2017-03-24 2018-09-27 Cedars-Sinai Medical Center Procédés et compositions pour la production d'épithélium de trompes de fallope
CN108048399B (zh) * 2017-11-13 2021-03-23 昆明医科大学 一种meth诱导树鼩多巴胺神经元原代细胞自噬的方法
JP2019106895A (ja) * 2017-12-15 2019-07-04 インダストリー‐ユニバーシティー コーぺレーション ファンデーション ハンヤン ユニバーシティ 神経幹細胞または神経前駆細胞からドーパミン神経細胞への分化方法
EP3768823A4 (fr) 2018-03-23 2022-03-09 Cedars-Sinai Medical Center Procédés d'utilisation de cellules des îlots pancréatiques
US11981918B2 (en) 2018-04-06 2024-05-14 Cedars-Sinai Medical Center Differentiation technique to generate dopaminergic neurons from induced pluripotent stem cells
US12241085B2 (en) 2018-04-06 2025-03-04 Cedars-Sinai Medical Center Human pluripotent stem cell derived neurodegenerative disease models on a microfluidic chip
JP2021532736A (ja) * 2018-06-06 2021-12-02 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California 神経幹細胞組成物および神経変性障害を処置するための方法
JP6798533B2 (ja) * 2018-07-26 2020-12-09 株式会社ニコン 細胞評価装置、インキュベータおよびプログラム
CN114375328B (zh) * 2019-09-06 2024-12-27 学校法人庆应义塾 包含胶质前体细胞的细胞聚集体的制备方法
WO2022098895A1 (fr) * 2020-11-04 2022-05-12 The Regents Of The University Of Michigan Dispositifs microfluidiques et procédés de développement de tissus du type tube neural ou sphéroïdes neuraux
JP7235027B2 (ja) * 2020-11-16 2023-03-08 株式会社ニコン 細胞評価装置、インキュベータおよびプログラム

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US20030068819A1 (en) * 2001-10-03 2003-04-10 Su-Chun Zhang Method of in vitro differentiation of transplantatable neural precursor cells from primate embryonic stem cells
US20030211605A1 (en) * 2001-05-01 2003-11-13 Lee Sang-Hun Derivation of midbrain dopaminergic neurons from embryonic stem cells

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US20020168763A1 (en) * 2000-11-30 2002-11-14 Yan Wen Liang Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same
US20030211605A1 (en) * 2001-05-01 2003-11-13 Lee Sang-Hun Derivation of midbrain dopaminergic neurons from embryonic stem cells
US20030068819A1 (en) * 2001-10-03 2003-04-10 Su-Chun Zhang Method of in vitro differentiation of transplantatable neural precursor cells from primate embryonic stem cells

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Also Published As

Publication number Publication date
IL173832A (en) 2011-02-28
CA2536588A1 (fr) 2005-03-10
GB2421029B (en) 2008-04-09
KR20080109943A (ko) 2008-12-17
AU2004269361A1 (en) 2005-03-10
CA2536588C (fr) 2018-04-24
EP1670901A2 (fr) 2006-06-21
IL198450A (en) 2011-01-31
GB0605851D0 (en) 2006-05-03
GB2421029A (en) 2006-06-14
WO2005021720A2 (fr) 2005-03-10
WO2005021720A3 (fr) 2005-05-19
JP2007503811A (ja) 2007-03-01
EP1670901A4 (fr) 2007-09-05
KR20060115351A (ko) 2006-11-08
IL173832A0 (en) 2006-07-05
JP5529561B2 (ja) 2014-06-25
JP2010162024A (ja) 2010-07-29

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