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AU2004241949A1 - Disease prevention and vaccination prior to thymic reactivations - Google Patents

Disease prevention and vaccination prior to thymic reactivations Download PDF

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Publication number
AU2004241949A1
AU2004241949A1 AU2004241949A AU2004241949A AU2004241949A1 AU 2004241949 A1 AU2004241949 A1 AU 2004241949A1 AU 2004241949 A AU2004241949 A AU 2004241949A AU 2004241949 A AU2004241949 A AU 2004241949A AU 2004241949 A1 AU2004241949 A1 AU 2004241949A1
Authority
AU
Australia
Prior art keywords
patient
cells
sex steroid
thymus
hsc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2004241949A
Other languages
English (en)
Inventor
Richard Boyd
Ann Patricia Chidgey
Gabrielle Lianne Goldberg
Jayne Suzanne Sutherland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norwood Immunology Ltd
Original Assignee
Norwood Immunology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/418,747 external-priority patent/US20040018180A1/en
Priority claimed from US10/419,068 external-priority patent/US20050002913A1/en
Priority claimed from US10/418,727 external-priority patent/US20040013641A1/en
Priority claimed from US10/419,066 external-priority patent/US20040037817A1/en
Priority claimed from US10/749,118 external-priority patent/US20040265285A1/en
Priority claimed from US10/748,831 external-priority patent/US20050020524A1/en
Priority claimed from US10/748,450 external-priority patent/US20040241842A1/en
Priority claimed from US10/749,122 external-priority patent/US20040259803A1/en
Application filed by Norwood Immunology Ltd filed Critical Norwood Immunology Ltd
Publication of AU2004241949A1 publication Critical patent/AU2004241949A1/en
Abandoned legal-status Critical Current

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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
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AU2004241949A 2003-04-18 2004-04-19 Disease prevention and vaccination prior to thymic reactivations Abandoned AU2004241949A1 (en)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US10/418,747 US20040018180A1 (en) 1999-04-15 2003-04-18 Stimulation of thymus for vaccination development
US10/419,068 2003-04-18
US10/418,747 2003-04-18
US10/419,068 US20050002913A1 (en) 1999-04-15 2003-04-18 Hematopoietic stem cell gene therapy
US10/419,066 2003-04-18
US10/418,727 US20040013641A1 (en) 1999-04-15 2003-04-18 Disease prevention by reactivation of the thymus
US10/419,066 US20040037817A1 (en) 1999-04-15 2003-04-18 Normalization of defective T cell responsiveness through manipulation of thymic regeneration
US10/418,727 2003-04-18
US52700103P 2003-12-05 2003-12-05
US60/527,001 2003-12-05
US10/748,831 2003-12-30
US10/749,118 US20040265285A1 (en) 1999-04-15 2003-12-30 Normalization of defective T cell responsiveness through manipulation of thymic regeneration
US10/748,450 2003-12-30
US10/748,831 US20050020524A1 (en) 1999-04-15 2003-12-30 Hematopoietic stem cell gene therapy
US10/749,122 2003-12-30
US10/748,450 US20040241842A1 (en) 1999-04-15 2003-12-30 Stimulation of thymus for vaccination development
US10/749,122 US20040259803A1 (en) 1999-04-15 2003-12-30 Disease prevention by reactivation of the thymus
US10/749,118 2003-12-30
PCT/US2004/011921 WO2004103271A2 (fr) 2003-04-18 2004-04-19 Prevention de maladies et vaccination avant reactivation thymique

Publications (1)

Publication Number Publication Date
AU2004241949A1 true AU2004241949A1 (en) 2004-12-02

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Application Number Title Priority Date Filing Date
AU2004241949A Abandoned AU2004241949A1 (en) 2003-04-18 2004-04-19 Disease prevention and vaccination prior to thymic reactivations

Country Status (6)

Country Link
EP (2) EP1620126A4 (fr)
JP (1) JP2007518699A (fr)
KR (1) KR20060022232A (fr)
AU (1) AU2004241949A1 (fr)
CA (1) CA2528521A1 (fr)
WO (2) WO2004094599A2 (fr)

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JP2007518699A (ja) * 2003-04-18 2007-07-12 ノーウッド・イミュノロジー・リミテッド 胸腺再生前の病気の予防およびワクチン接種
CN100425288C (zh) * 2005-01-28 2008-10-15 北京金迪克生物技术研究所 鼻腔喷雾型流感病毒灭活疫苗及其制备方法
GB0519303D0 (en) * 2005-09-21 2005-11-02 Oxford Biomedica Ltd Chemo-immunotherapy method
EP2288359B1 (fr) * 2008-04-21 2019-10-02 Tissue Regeneration Therapeutics Inc. Cellules périvasculaires génétiquement modifiées de cordon ombilical humain pour une prophylaxie ou un traitement d'agents biologiques ou chimiques
US20110144032A1 (en) * 2008-08-08 2011-06-16 Christopher Hovens Biological applications of steroid binding domains
US20110086051A1 (en) * 2009-10-08 2011-04-14 Dartmouth-Hitchcock Clinic System and method for monitoring and optimizing immune status in transplant recipients
EP2906223A1 (fr) * 2012-10-15 2015-08-19 CHAMAELEO Pharma Bvba Fosfestrol pour une utilisation dans le traitement curatif ou palliatif du cancer chez les mammifères femelles
WO2018134370A1 (fr) 2017-01-20 2018-07-26 Immune System Regulation Holding Ab Nouveaux composés (immunorhélines)
CN110431147A (zh) 2017-01-20 2019-11-08 免疫系统调节控股有限公司 新化合物(免疫刺激肽-细胞内感染)
WO2018153961A1 (fr) * 2017-02-22 2018-08-30 Immune System Regulation Holding Ab Hormones de libération des gonadotropines destinées à être utilisées en tant qu'adjuvants immunothérapeutiques

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP977899A0 (en) * 1999-04-15 1999-05-13 Monash University Improvement of t cell mediated immunity
US20040258672A1 (en) * 1999-04-15 2004-12-23 Monash University Graft acceptance through manipulation of thymic regeneration
US20020086000A1 (en) * 1999-04-15 2002-07-04 Richard Boyd Stimulation of thymus for vaccination development
AP2003002800A0 (en) * 2000-10-13 2003-06-30 Richard Boyd Hematopoietic stem cell gene therapy
NZ525830A (en) * 2000-10-13 2005-07-29 Norwood Immunology Ltd Disease prevention by reactivation of the thymus
JP2007518699A (ja) * 2003-04-18 2007-07-12 ノーウッド・イミュノロジー・リミテッド 胸腺再生前の病気の予防およびワクチン接種

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EP1620126A2 (fr) 2006-02-01
WO2004094599A2 (fr) 2004-11-04
CA2528521A1 (fr) 2004-12-02
EP1620126A4 (fr) 2007-07-04
KR20060022232A (ko) 2006-03-09
WO2004103271A2 (fr) 2004-12-02
EP1620545A4 (fr) 2007-07-04

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