AU2003301095A1 - 4(spiropiperidinyl)methyl substituted pyrrolidines as modulators of chemokine receptor activity - Google Patents
4(spiropiperidinyl)methyl substituted pyrrolidines as modulators of chemokine receptor activityInfo
- Publication number
- AU2003301095A1 AU2003301095A1 AU2003301095A AU2003301095A AU2003301095A1 AU 2003301095 A1 AU2003301095 A1 AU 2003301095A1 AU 2003301095 A AU2003301095 A AU 2003301095A AU 2003301095 A AU2003301095 A AU 2003301095A AU 2003301095 A1 AU2003301095 A1 AU 2003301095A1
- Authority
- AU
- Australia
- Prior art keywords
- spiropiperidinyl
- modulators
- chemokine receptor
- receptor activity
- methyl substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43612702P | 2002-12-23 | 2002-12-23 | |
| US60/436,127 | 2002-12-23 | ||
| PCT/US2003/040491 WO2004058763A1 (en) | 2002-12-23 | 2003-12-19 | 4(spiropiperidinyl)methyl substituted pyrrolidines as modulators of chemokine receptor activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003301095A1 true AU2003301095A1 (en) | 2004-07-22 |
Family
ID=32682344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003301095A Abandoned AU2003301095A1 (en) | 2002-12-23 | 2003-12-19 | 4(spiropiperidinyl)methyl substituted pyrrolidines as modulators of chemokine receptor activity |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2003301095A1 (en) |
| WO (1) | WO2004058763A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1786815B1 (en) | 2003-09-10 | 2011-08-24 | Virochem Pharma Inc. | Spiro compounds and methods for the modulation of chemokine receptor activity |
| JPWO2007013661A1 (en) * | 2005-07-26 | 2009-02-12 | 千寿製薬株式会社 | Ophthalmic transdermal preparation |
| CN103242276B (en) * | 2013-05-07 | 2014-07-16 | 白银安杰利生化科技有限公司 | Synthesis method of 2, 2-dimethyltetrahydro-2H-pyran-4-carboxylic acid |
| GB201617758D0 (en) | 2016-10-20 | 2016-12-07 | Almac Discovery Limited | Pharmaceutical compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6166037A (en) * | 1997-08-28 | 2000-12-26 | Merck & Co., Inc. | Pyrrolidine and piperidine modulators of chemokine receptor activity |
| US6498161B1 (en) * | 1999-04-06 | 2002-12-24 | Merck & Co., Inc. | Pyrrolidine modulators of chemokine receptor activity |
-
2003
- 2003-12-19 WO PCT/US2003/040491 patent/WO2004058763A1/en not_active Ceased
- 2003-12-19 AU AU2003301095A patent/AU2003301095A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004058763A1 (en) | 2004-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |