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AU2003300720A1 - C-8 linked pyrrolo(2,1-c)(1,4)benzodiazepine-acridone/acridine hybrids - Google Patents

C-8 linked pyrrolo(2,1-c)(1,4)benzodiazepine-acridone/acridine hybrids

Info

Publication number
AU2003300720A1
AU2003300720A1 AU2003300720A AU2003300720A AU2003300720A1 AU 2003300720 A1 AU2003300720 A1 AU 2003300720A1 AU 2003300720 A AU2003300720 A AU 2003300720A AU 2003300720 A AU2003300720 A AU 2003300720A AU 2003300720 A1 AU2003300720 A1 AU 2003300720A1
Authority
AU
Australia
Prior art keywords
acridone
benzodiazepine
acridine
hybrids
linked pyrrolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003300720A
Inventor
Ahmed Kamal
Pogula Praveen Kumar
Gujjar Ramesh
Poddutoori Ramulu
Olepu Srinivas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Council of Scientific and Industrial Research CSIR
Original Assignee
Council of Scientific and Industrial Research CSIR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council of Scientific and Industrial Research CSIR filed Critical Council of Scientific and Industrial Research CSIR
Publication of AU2003300720A1 publication Critical patent/AU2003300720A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003300720A 2003-12-31 2003-12-31 C-8 linked pyrrolo(2,1-c)(1,4)benzodiazepine-acridone/acridine hybrids Abandoned AU2003300720A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2003/000464 WO2005063760A1 (en) 2003-12-31 2003-12-31 C-8 LINKED PYRROLO[2,1-c][1,4]BENZODIAZEPINE-ACRIDONE/ACRIDINE HYBRIDS

Publications (1)

Publication Number Publication Date
AU2003300720A1 true AU2003300720A1 (en) 2005-07-21

Family

ID=34717581

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003300720A Abandoned AU2003300720A1 (en) 2003-12-31 2003-12-31 C-8 linked pyrrolo(2,1-c)(1,4)benzodiazepine-acridone/acridine hybrids

Country Status (4)

Country Link
JP (1) JP4718328B2 (en)
AU (1) AU2003300720A1 (en)
GB (1) GB2424884B (en)
WO (1) WO2005063760A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007054954A1 (en) * 2005-11-10 2007-05-18 Council Of Scientific & Industrial Research A novel pyrrolo[2,1-c][1,4]benzodiazepine hybrid and a process for the preparation thereof
ATE543826T1 (en) * 2007-08-01 2012-02-15 Council Scient Ind Res PYRROLOÄ2,1-CUÄ1,4ÜBENZODIAZEPINE GLYCOSIDE-PRODRU S SUITABLE AS SELECTIVE ANTITUMOR AGENTS
IL301638B2 (en) 2017-09-29 2024-09-01 Daiichi Sankyo Co Ltd Conjugation of an antibody with a pyrrolobenzodiazepine derivative

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
GB9621795D0 (en) * 1996-10-18 1996-12-11 Xenova Ltd Pharmaceutical compounds
DK1193270T3 (en) * 1998-08-27 2003-09-15 Spirogen Ltd pyrrolobenzodiazepines

Also Published As

Publication number Publication date
JP4718328B2 (en) 2011-07-06
GB0614754D0 (en) 2006-09-06
JP2007528344A (en) 2007-10-11
WO2005063760A1 (en) 2005-07-14
GB2424884B (en) 2008-06-11
GB2424884A (en) 2006-10-11

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase