AU2003233238A1 - Fap-activated anti-tumor prodrugs - Google Patents
Fap-activated anti-tumor prodrugsInfo
- Publication number
- AU2003233238A1 AU2003233238A1 AU2003233238A AU2003233238A AU2003233238A1 AU 2003233238 A1 AU2003233238 A1 AU 2003233238A1 AU 2003233238 A AU2003233238 A AU 2003233238A AU 2003233238 A AU2003233238 A AU 2003233238A AU 2003233238 A1 AU2003233238 A1 AU 2003233238A1
- Authority
- AU
- Australia
- Prior art keywords
- fap
- activated anti
- prodrugs
- tumor
- tumor prodrugs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02010552 | 2002-05-10 | ||
| EP02010552.4 | 2002-05-10 | ||
| PCT/EP2003/004713 WO2003094972A2 (en) | 2002-05-10 | 2003-05-06 | Fap-activated anti-tumor prodrugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003233238A8 AU2003233238A8 (en) | 2003-11-11 |
| AU2003233238A1 true AU2003233238A1 (en) | 2003-11-11 |
Family
ID=29414680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003233238A Abandoned AU2003233238A1 (en) | 2002-05-10 | 2003-05-06 | Fap-activated anti-tumor prodrugs |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1506221A2 (en) |
| AU (1) | AU2003233238A1 (en) |
| WO (1) | WO2003094972A2 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007087131A2 (en) * | 2006-01-05 | 2007-08-02 | The Johns Hopkins University | Peptide prodrugs |
| IL249370B (en) | 2014-06-13 | 2022-06-01 | Tufts College | Fap-activated medical substances and their related uses |
| US9737556B2 (en) | 2014-06-13 | 2017-08-22 | Trustees Of Tufts College | FAP-activated therapeutic agents, and uses related thereto |
| CA3203072A1 (en) | 2020-12-22 | 2022-06-30 | Andrea CASAZZA | Compounds comprising a tetrapeptidic moiety |
| WO2022167664A1 (en) | 2021-02-07 | 2022-08-11 | Cobiores Nv | Compounds comprising a tetrapeptidic moiety |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU708475B2 (en) * | 1995-10-18 | 1999-08-05 | Merck & Co., Inc. | Conjugates useful in the treatment of benign prostatic hyperplasia |
| WO2000033888A2 (en) * | 1998-12-11 | 2000-06-15 | Coulter Pharmaceutical, Inc. | Prodrug compounds and process for preparation thereof |
| US6613879B1 (en) * | 1999-05-14 | 2003-09-02 | Boehringer Ingelheim Pharma Kg | FAP-activated anti-tumour compounds |
| AU2002316539C1 (en) * | 2001-06-11 | 2008-10-30 | Medarex, Inc. | CD10-activated prodrug compounds |
-
2003
- 2003-05-06 WO PCT/EP2003/004713 patent/WO2003094972A2/en not_active Ceased
- 2003-05-06 AU AU2003233238A patent/AU2003233238A1/en not_active Abandoned
- 2003-05-06 EP EP03727438A patent/EP1506221A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003094972A2 (en) | 2003-11-20 |
| EP1506221A2 (en) | 2005-02-16 |
| AU2003233238A8 (en) | 2003-11-11 |
| WO2003094972A3 (en) | 2004-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase | ||
| TH | Corrigenda |
Free format text: IN VOL 18, NO 2, PAGE(S) 488 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG, APPLICATION NO. 2003233238, UNDER INID(43) CORRECT THE PUBLICATION DATE TO READ 24.11.2003 |