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AU2003233279A1 - Non-covalent inhibitors of cysteine proteases with atripeptide backbone - Google Patents

Non-covalent inhibitors of cysteine proteases with atripeptide backbone

Info

Publication number
AU2003233279A1
AU2003233279A1 AU2003233279A AU2003233279A AU2003233279A1 AU 2003233279 A1 AU2003233279 A1 AU 2003233279A1 AU 2003233279 A AU2003233279 A AU 2003233279A AU 2003233279 A AU2003233279 A AU 2003233279A AU 2003233279 A1 AU2003233279 A1 AU 2003233279A1
Authority
AU
Australia
Prior art keywords
atripeptide
backbone
cysteine proteases
covalent inhibitors
covalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003233279A
Other versions
AU2003233279A8 (en
Inventor
Robert Menard
Enrico O. Purisima
Traian Sulea
Jing Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Council of Canada
Original Assignee
National Research Council of Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Council of Canada filed Critical National Research Council of Canada
Publication of AU2003233279A8 publication Critical patent/AU2003233279A8/en
Publication of AU2003233279A1 publication Critical patent/AU2003233279A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2003233279A 2002-05-15 2003-05-15 Non-covalent inhibitors of cysteine proteases with atripeptide backbone Abandoned AU2003233279A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38027702P 2002-05-15 2002-05-15
US60/380,277 2002-05-15
PCT/CA2003/000730 WO2003097664A2 (en) 2002-05-15 2003-05-15 Non-covalent inhibitors of cysteine proteases with atripeptide backbone

Publications (2)

Publication Number Publication Date
AU2003233279A8 AU2003233279A8 (en) 2003-12-02
AU2003233279A1 true AU2003233279A1 (en) 2003-12-02

Family

ID=29549946

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003233279A Abandoned AU2003233279A1 (en) 2002-05-15 2003-05-15 Non-covalent inhibitors of cysteine proteases with atripeptide backbone

Country Status (2)

Country Link
AU (1) AU2003233279A1 (en)
WO (1) WO2003097664A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0604187D0 (en) * 2006-03-02 2006-04-12 Fusion Antibodies Ltd Peptide and uses thereof
GB0724951D0 (en) 2007-12-20 2008-01-30 Lytix Biopharma As Compounds
GB0818072D0 (en) 2008-10-02 2008-11-05 Lytix Biopharma As Compounds
US20140288007A1 (en) * 2011-11-04 2014-09-25 Oral Health Australia Pty. Ltd. Gingipain inhibitory propeptides
EP2633855A1 (en) 2012-03-01 2013-09-04 Veterinärmedizinische Universität Wien Protease inhibitors for treating Trichomonas gallinae infections

Also Published As

Publication number Publication date
AU2003233279A8 (en) 2003-12-02
WO2003097664A3 (en) 2004-05-06
WO2003097664A2 (en) 2003-11-27

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase