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AU2003232362A1 - 4-pyrazol-phenylalanine derivatives as ace-nep inhibitors - Google Patents

4-pyrazol-phenylalanine derivatives as ace-nep inhibitors

Info

Publication number
AU2003232362A1
AU2003232362A1 AU2003232362A AU2003232362A AU2003232362A1 AU 2003232362 A1 AU2003232362 A1 AU 2003232362A1 AU 2003232362 A AU2003232362 A AU 2003232362A AU 2003232362 A AU2003232362 A AU 2003232362A AU 2003232362 A1 AU2003232362 A1 AU 2003232362A1
Authority
AU
Australia
Prior art keywords
pyrazol
ace
phenylalanine derivatives
nep inhibitors
nep
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003232362A
Other versions
AU2003232362A8 (en
Inventor
Anthony William James Cooper
Jacqueline Elizabeth Mordaunt
Simon Peace
Paul William Smith
Steven Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AU2003232362A8 publication Critical patent/AU2003232362A8/en
Publication of AU2003232362A1 publication Critical patent/AU2003232362A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003232362A 2002-06-07 2003-06-05 4-pyrazol-phenylalanine derivatives as ace-nep inhibitors Abandoned AU2003232362A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0213122A GB0213122D0 (en) 2002-06-07 2002-06-07 Compounds
GB0213122.5 2002-06-07
PCT/GB2003/002502 WO2003104189A2 (en) 2002-06-07 2003-06-05 Compounds

Publications (2)

Publication Number Publication Date
AU2003232362A8 AU2003232362A8 (en) 2003-12-22
AU2003232362A1 true AU2003232362A1 (en) 2003-12-22

Family

ID=9938170

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003232362A Abandoned AU2003232362A1 (en) 2002-06-07 2003-06-05 4-pyrazol-phenylalanine derivatives as ace-nep inhibitors

Country Status (3)

Country Link
AU (1) AU2003232362A1 (en)
GB (1) GB0213122D0 (en)
WO (1) WO2003104189A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7855291B2 (en) 2005-12-29 2010-12-21 Lexicon Pharmaceuticals, Inc. Process for the preparation of substituted phenylalanines
AU2006337137B2 (en) 2005-12-29 2012-06-14 Tersera Therapeutics Llc Multicyclic amino acid derivatives and methods of their use
US7897763B2 (en) 2005-12-29 2011-03-01 Lexicon Pharmaceuticals, Inc. Process for the preparation of substituted phenylalanines
ES2848152T3 (en) 2007-08-24 2021-08-05 Tersera Therapeutics Llc Methods for preparing compounds based on 4-phenyl-6- (2,2,2-trifluoro-1-phenylethoxy) pyrimidine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277737B1 (en) * 1995-12-28 1997-11-12 Zambon Spa TIOLIC DERIVATIVES FOR METALLOPEPTIDASE INHIBITIVE ACTIVITY
GB0203665D0 (en) * 2002-02-15 2002-04-03 Glaxo Group Ltd Process

Also Published As

Publication number Publication date
GB0213122D0 (en) 2002-07-17
AU2003232362A8 (en) 2003-12-22
WO2003104189A2 (en) 2003-12-18
WO2003104189A3 (en) 2005-09-01

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase