AU2003226955A1 - Translocation dependent complementation for drug screening - Google Patents
Translocation dependent complementation for drug screeningInfo
- Publication number
- AU2003226955A1 AU2003226955A1 AU2003226955A AU2003226955A AU2003226955A1 AU 2003226955 A1 AU2003226955 A1 AU 2003226955A1 AU 2003226955 A AU2003226955 A AU 2003226955A AU 2003226955 A AU2003226955 A AU 2003226955A AU 2003226955 A1 AU2003226955 A1 AU 2003226955A1
- Authority
- AU
- Australia
- Prior art keywords
- drug screening
- translocation
- dependent complementation
- complementation
- translocation dependent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000001419 dependent effect Effects 0.000 title 1
- 238000007877 drug screening Methods 0.000 title 1
- 230000005945 translocation Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43595—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from coelenteratae, e.g. medusae
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200200591 | 2002-04-19 | ||
| DKPA200200591 | 2002-04-19 | ||
| DKPA200200896 | 2002-06-13 | ||
| DKPA200200896 | 2002-06-13 | ||
| DKPA200201029 | 2002-07-01 | ||
| DKPA200201029 | 2002-07-01 | ||
| PCT/DK2002/000882 WO2003089464A1 (en) | 2002-04-19 | 2002-12-19 | Two green fluorescent protein fragments and their use in a method for detecting protein - protein interactions |
| AU2002358466 | 2002-12-19 | ||
| PCT/DK2003/000266 WO2003089627A1 (en) | 2002-04-19 | 2003-04-22 | Translocation dependent complementation for drug screening |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003226955A1 true AU2003226955A1 (en) | 2003-11-03 |
Family
ID=29255411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003226955A Abandoned AU2003226955A1 (en) | 2002-04-19 | 2003-04-22 | Translocation dependent complementation for drug screening |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1509596A1 (en) |
| JP (1) | JP2005527210A (en) |
| AU (1) | AU2003226955A1 (en) |
| WO (1) | WO2003089627A1 (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7166424B2 (en) * | 1998-02-02 | 2007-01-23 | Odyssey Thera Inc. | Fragments of fluorescent proteins for protein fragment complementation assays |
| AU2004315485A1 (en) * | 2003-10-24 | 2005-08-18 | The Regents Of The University Of California | Self-assembling split-fluorescent protein systems |
| GB0327143D0 (en) * | 2003-11-21 | 2003-12-24 | Univ Belfast | Assay |
| EP2400030B1 (en) * | 2004-05-18 | 2016-01-20 | The Board of Trustees of the Leland Stanford Junior University | Detection of protein translocation by beta-galactosidase reporter fragment complementation |
| MXPA06013470A (en) * | 2004-05-19 | 2008-03-13 | Uinv Kobenhavns | Adam12, a novel marker for abnormal cell function. |
| US20060040338A1 (en) * | 2004-08-18 | 2006-02-23 | Odyssey Thera, Inc. | Pharmacological profiling of drugs with cell-based assays |
| EP1674478A1 (en) * | 2004-12-22 | 2006-06-28 | GSF-Forschungszentrum für Umwelt und Gesundheit GmbH | Fusion proteins and method for determining protein-protein-interactions in living cells and cell lysates, nucleic acids encoding these fusion proteins, as well as vectors and kits containing these |
| JP2008546411A (en) * | 2005-06-21 | 2008-12-25 | ディスカヴァーエックス インコーポレイテッド | Fission index assay |
| GB201503133D0 (en) | 2015-02-24 | 2015-04-08 | Ucl Business Plc And Syncona Partners Llp | Chimeric protein |
| CN112279921B (en) * | 2019-07-11 | 2025-07-29 | 厦门大学 | Complexes for intracellular delivery of molecules |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000073437A1 (en) * | 1999-05-27 | 2000-12-07 | Merck Frosst Canada & Co. | Assays for caspase activity using green fluorescent proteins |
| AU2001261499A1 (en) * | 2000-05-12 | 2001-11-26 | Yale University | Methods of detecting interactions between proteins, peptides or libraries thereof using fusion proteins |
-
2003
- 2003-04-22 WO PCT/DK2003/000266 patent/WO2003089627A1/en not_active Ceased
- 2003-04-22 EP EP03746819A patent/EP1509596A1/en not_active Withdrawn
- 2003-04-22 AU AU2003226955A patent/AU2003226955A1/en not_active Abandoned
- 2003-04-22 JP JP2003586340A patent/JP2005527210A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003089627A1 (en) | 2003-10-30 |
| JP2005527210A (en) | 2005-09-15 |
| EP1509596A1 (en) | 2005-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |