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AU2003205536A1 - Anti-retroviral 5,6-disubstituted acyclopyrimidine nucleoside derivatives - Google Patents

Anti-retroviral 5,6-disubstituted acyclopyrimidine nucleoside derivatives

Info

Publication number
AU2003205536A1
AU2003205536A1 AU2003205536A AU2003205536A AU2003205536A1 AU 2003205536 A1 AU2003205536 A1 AU 2003205536A1 AU 2003205536 A AU2003205536 A AU 2003205536A AU 2003205536 A AU2003205536 A AU 2003205536A AU 2003205536 A1 AU2003205536 A1 AU 2003205536A1
Authority
AU
Australia
Prior art keywords
retroviral
disubstituted
nucleoside derivatives
acyclopyrimidine nucleoside
acyclopyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003205536A
Inventor
Anne Marie Boel
Berit Dahan
Nasser R. El-Brollosy
Per Trolle Jorgensen
Claus Nielsen
Erik Bjerregaard Pedersen
Bent Faber Vestergaard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Statens Serum Institut SSI
Syddansk Universitet
Original Assignee
Statens Serum Institut SSI
Syddansk Universitet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Serum Institut SSI, Syddansk Universitet filed Critical Statens Serum Institut SSI
Publication of AU2003205536A1 publication Critical patent/AU2003205536A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003205536A 2002-01-11 2003-01-10 Anti-retroviral 5,6-disubstituted acyclopyrimidine nucleoside derivatives Abandoned AU2003205536A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200200044 2002-01-11
DKPA200200044 2002-01-11
PCT/DK2003/000014 WO2003057677A1 (en) 2002-01-11 2003-01-10 Anti-retroviral 5,6-disubstituted acyclopyrimidine nucleoside derivatives

Publications (1)

Publication Number Publication Date
AU2003205536A1 true AU2003205536A1 (en) 2003-07-24

Family

ID=8160984

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003205536A Abandoned AU2003205536A1 (en) 2002-01-11 2003-01-10 Anti-retroviral 5,6-disubstituted acyclopyrimidine nucleoside derivatives

Country Status (2)

Country Link
AU (1) AU2003205536A1 (en)
WO (1) WO2003057677A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0714880A2 (en) 2006-07-24 2013-05-21 Gilead Sciences Inc hiv reverse transcriptase inhibitors
US8354421B2 (en) 2007-06-29 2013-01-15 Korea Research Insitute Of Chemical Technology HIV reverse transcriptase inhibitors
KR101551238B1 (en) 2007-06-29 2015-09-09 한국화학연구원 Novel hiv reverse transcriptase inhibitors
WO2009085797A1 (en) 2007-12-21 2009-07-09 Gilead Sciences, Inc. Processes for preparing hiv reverse transcriptase inhibitors
MX351299B (en) 2011-11-11 2017-10-10 Pfizer 2-THIOPIRIMIDINONES.
CN102816184B (en) * 2012-09-07 2015-11-18 山东大学 (2-(2-oxygen base-4-thiopyrimidine) oxyethyl group) methyl-phosphorous acid ester derivative and preparation and application thereof
CN107531647A (en) 2015-05-05 2018-01-02 辉瑞大药厂 2 thiopyrimidine ketones

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU205917B (en) * 1989-09-29 1992-07-28 Mitsubishi Chem Ind Process for producing 6-substituted pyrimidine derivatives and antiviral pharmaceutical compositions containing them as active components

Also Published As

Publication number Publication date
WO2003057677A1 (en) 2003-07-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase