AU2003287108A1 - Fusion of the e2 protein of csfv with kdel , vts and/or ubiquitin for expression in transgenic plants for vaccine production - Google Patents

Fusion of the e2 protein of csfv with kdel , vts and/or ubiquitin for expression in transgenic plants for vaccine production

Info

Publication number: AU2003287108A1
Authority: AU; Australia
Prior art keywords: csfv; kdel; vts; ubiquitin; fusion
Prior art date: 2002-12-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2003287108A

Other versions

AU2003287108A8 (en

Inventor

Krystyna Bienkowska-Szewczyk

Magdalena Czaplinska

Jolanta Ficinska

Monika Gut-Winiarska

Femiak Iowona

Jozef Kapusta

Malgorzata Kesik

Andrzej B. Legocki

Olesia Lisowa

Katarzyna Miedzinska

Andrzej Plucienniczak

Tomasz Pniewski

Anna Porebska

Boguslaw Szewczyk

Jolanta Tyborowska

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

INSTITUTE OF BIOORGANIC CHEMISTRY

University of Gdansk

Institute of Biotechnology and Antibiotics

Original Assignee

INST OF BIOORG CHEMISTRY

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-04

Filing date

2003-12-04

Publication date

2004-06-23

2003-12-04 Application filed by INST OF BIOORG CHEMISTRY filed Critical INST OF BIOORG CHEMISTRY

2004-06-23 Publication of AU2003287108A1 publication Critical patent/AU2003287108A1/en

2004-06-23 Publication of AU2003287108A8 publication Critical patent/AU2003287108A8/en

Status Abandoned legal-status Critical Current

Links

102000044159 Ubiquitin Human genes 0.000 title 1
108090000848 Ubiquitin Proteins 0.000 title 1
LXWYCLOUQZZDBD-LIYNQYRNSA-N csfv Chemical compound C([C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O)C1=CC=C(O)C=C1 LXWYCLOUQZZDBD-LIYNQYRNSA-N 0.000 title 1
230000004927 fusion Effects 0.000 title 1
102000004169 proteins and genes Human genes 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1
230000009261 transgenic effect Effects 0.000 title 1
229960005486 vaccine Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/517—Plant cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/95—Fusion polypeptide containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Biochemistry (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Biophysics (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Gastroenterology & Hepatology (AREA)
Cell Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Mycology (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

AU2003287108A 2002-12-04 2003-12-04 Fusion of the e2 protein of csfv with kdel , vts and/or ubiquitin for expression in transgenic plants for vaccine production Abandoned AU2003287108A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
PLP.357518		2002-12-04
PL357518A PL201420B1 (en)	2002-12-04	2002-12-04	Chimeric protein, sequence, construction, vegetable cell, method of obtaining chimeric protein and transgenic plant, application of transgenic plant and chimeric protein
PCT/PL2003/000136 WO2004050692A2 (en)	2002-12-04	2003-12-04	Fusion of the e2 protein of csfv with kdel , vts and/or ubiquitin for expression in transgenic plants for vaccine production

Publications (2)

Publication Number	Publication Date
AU2003287108A1 true AU2003287108A1 (en)	2004-06-23
AU2003287108A8 AU2003287108A8 (en)	2004-06-23

Family

ID=32464756

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2003287108A Abandoned AU2003287108A1 (en)	2002-12-04	2003-12-04	Fusion of the e2 protein of csfv with kdel , vts and/or ubiquitin for expression in transgenic plants for vaccine production

Country Status (3)

Country	Link
AU (1)	AU2003287108A1 (en)
PL (1)	PL201420B1 (en)
WO (1)	WO2004050692A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2008504033A (en) *	2004-06-25	2008-02-14	アルター・バイオサイエンス・コーポレーション	Production of tissue factor in plants
RU2727847C2 (en) *	2016-05-12	2020-07-24	Биоэппликейшнз Инк.	Herbal composition for swine fever vaccination and a method for preparation thereof
CN107619435B (en) *	2017-09-19	2021-03-16	中国农业科学院上海兽医研究所	Preparation and application of antigenic epitope and antibody of a swine fever virus E2 protein
CN109324193A (en) *	2018-12-07	2019-02-12	中国农业科学院兰州兽医研究所	A visual rapid detection kit for swine fever virus antibody and its application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6068994A (en) *	1989-08-07	2000-05-30	Chiron Corporation	Ubiquitin expression system
EP0728213B2 (en) *	1993-11-09	2008-12-10	E.I. Du Pont De Nemours And Company	Transgenic fructan accumulating crops and methods for their production
US6319503B1 (en) *	1998-02-19	2001-11-20	Proteinix Company	Heat shock fusion-based vaccine system
WO2003013598A2 (en) *	2001-08-09	2003-02-20	Lam Dominic M K	Novel vaccine compositions and methods of vaccine preparation for veterinary and human diseases

2002
- 2002-12-04 PL PL357518A patent/PL201420B1/en not_active IP Right Cessation
2003
- 2003-12-04 WO PCT/PL2003/000136 patent/WO2004050692A2/en not_active Ceased
- 2003-12-04 AU AU2003287108A patent/AU2003287108A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2004050692A3 (en)	2004-12-09
PL357518A1 (en)	2004-06-14
AU2003287108A8 (en)	2004-06-23
WO2004050692A2 (en)	2004-06-17
PL201420B1 (en)	2009-04-30

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WO2005003313A3 (en)	2005-07-21	Methods and compositions for enhanced protein expression and purification
AU2002356861A1 (en)	2003-05-06	Fibrin membrane and methods for its preparation- application to artificial skin
EP1660638A4 (en)	2009-02-18	Lipoparticles comprising proteins, methods of making, and using the same
AU2003239365A1 (en)	2003-11-17	Recombinant glycosyltransferase fusion proteins
IL171926A0 (en)	2006-04-10	Glp-1 analog fusion proteins
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AU2003265637A1 (en)	2004-03-19	Nucleotide sequences encoding cry1bb proteins for enhanced expression in plants
WO2003057174A3 (en)	2004-03-04	Methods and compositions for protein expression and purification
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AU2003287108A1 (en)	2004-06-23	Fusion of the e2 protein of csfv with kdel , vts and/or ubiquitin for expression in transgenic plants for vaccine production
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AU2002221010A1 (en)	2002-06-11	Vectors for expressing heterologous peptides at the amino-terminus of potyvirus coat protein, methods for use thereof, plants infected with same and methods of vaccination using same
AU2002311620A1 (en)	2003-01-21	Methods of making and using expression constructs for the expression of recombinant proteins
AU2003225612A1 (en)	2003-09-09	Expression of hiv-related proteins in plants
AU2003264075A8 (en)	2004-03-11	Active fusion proteins and method for the production thereof

Legal Events

Date	Code	Title	Description
2005-08-18	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase
2005-09-01	TH	Corrigenda	Free format text: IN VOL 18, NO 29, PAGE(S) 7833 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME INSTITUTE OF BIOORGANIC CHEMISTRY, APPLICATION NO. 2003287108, UNDER INID (71) CORRECT THE NAME TO READ INSTITUTE OF BIOORGANIC CHEMISTRY; INSTITUTE OF BIOTECHNOLOGY ANTIBIOTICS; UNIWERSITY OF GDANSK