AU2003267907A1 - Prothrombin purification - Google Patents

Prothrombin purification

Info

Publication number: AU2003267907A1
Authority: AU; Australia
Prior art keywords: prothrombin; purification; prothrombin purification
Prior art date: 2002-12-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2003267907A

Inventor

Peter Aizawa

Stefan Winge

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Swedish Orphan Biovitrum AB

Original Assignee

Biovitrum AB

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-02

Filing date

2003-10-06

Publication date

2004-06-23

2003-10-06 Application filed by Biovitrum AB filed Critical Biovitrum AB

2004-06-23 Publication of AU2003267907A1 publication Critical patent/AU2003267907A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6429—Thrombin (3.4.21.5)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6432—Coagulation factor Xa (3.4.21.6)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21006—Coagulation factor Xa (3.4.21.6)

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AU2003267907A 2002-12-02 2003-10-06 Prothrombin purification Abandoned AU2003267907A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
SE0203551A SE0203551D0 (en)	2002-12-02	2002-12-02	Prothrombin purification
SE0203551-7		2002-12-02
PCT/SE2003/001549 WO2004050904A1 (en)	2002-12-02	2003-10-06	Prothrombin purification

Publications (1)

Publication Number	Publication Date
AU2003267907A1 true AU2003267907A1 (en)	2004-06-23

Family

ID=20289726

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2003267907A Abandoned AU2003267907A1 (en)	2002-12-02	2003-10-06	Prothrombin purification

Country Status (3)

Country	Link
AU (1)	AU2003267907A1 (en)
SE (1)	SE0203551D0 (en)
WO (1)	WO2004050904A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9956272B2 (en)	2007-05-30	2018-05-01	Bio Products Laboratory Limited	Methods for preparing factor X, activated factor X, inactivated factor X and inactivated factor Xa, and pharmaceutical compositions comprising same
GB0710321D0 (en)	2007-05-30	2007-07-11	Nhs Blood & Transplant	Method
EP2553095B1 (en) *	2010-03-30	2016-10-12	Octapharma AG	A process for purifying vitamin K dependent proteins such as coagulation factor IX
US9011846B2 (en) *	2011-05-02	2015-04-21	Biomet Biologics, Llc	Thrombin isolated from blood and blood fractions
MX2020004151A (en)	2017-10-30	2020-08-13	Takeda Pharmaceuticals Co	Environmentally compatible detergents for inactivation of lipid-enveloped viruses.
CN119709710A (en) *	2024-12-27	2025-03-28	广东双林生物制药有限公司	Method for purifying and activating prothrombin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3877529T2 (en) *	1987-10-23	1996-11-07	Centre Regional De Transfusion	Production of highly purified human factor IX and other plasma protein concentrate and its therapeutic use.
GB8729822D0 (en) *	1987-12-22	1988-02-03	Central Blood Lab Authority	Chemical process
IT1262899B (en) *	1992-03-27	1996-07-22	Sclavo Spa	PROCESS FOR THE INSULATION OF FACTOR IX, FACTOR X AND FACTOR II HIGHLY PURIFIED FROM THE PROTROMBINIC COMPLEX OR HUMAN PLASMA
US5219995A (en) *	1992-07-14	1993-06-15	Alpha Therapeutic Corporation	Plasma fraction purification
EP0796623B1 (en) *	1996-03-20	2005-05-25	Baxter Aktiengesellschaft	Pharmaceutical preparation for the treatment of blood coagulation disorders
JPH11228443A (en) *	1998-02-07	1999-08-24	Chemo Sero Therapeut Res Inst	New activation of prothrombin and production of thrombin on basis of the method
US6245548B1 (en) *	2000-03-09	2001-06-12	American National Red Cross	Activation of pure prothrombin to thrombin with about 30% to about 40% sodium citrate

2002
- 2002-12-02 SE SE0203551A patent/SE0203551D0/en unknown
2003
- 2003-10-06 AU AU2003267907A patent/AU2003267907A1/en not_active Abandoned
- 2003-10-06 WO PCT/SE2003/001549 patent/WO2004050904A1/en not_active Ceased

Also Published As

Publication number	Publication date
WO2004050904A1 (en)	2004-06-17
SE0203551D0 (en)	2002-12-02

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AU2003259219A1 (en)	2004-02-09	Superprimer
AU2003279366A1 (en)	2004-06-07	Novel compounds
AU2003272454A1 (en)	2004-04-08	Protein purification
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AU2003304383A1 (en)	2005-02-25	OBTUSIFOLIOL 14a- DEMETHYLASE
AU2003900554A0 (en)	2003-02-20	Thrombin purification

Legal Events

Date	Code	Title	Description
2005-08-18	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase