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AU2003267145A1 - Highly specific modulators of gtpases for target validation - Google Patents

Highly specific modulators of gtpases for target validation

Info

Publication number
AU2003267145A1
AU2003267145A1 AU2003267145A AU2003267145A AU2003267145A1 AU 2003267145 A1 AU2003267145 A1 AU 2003267145A1 AU 2003267145 A AU2003267145 A AU 2003267145A AU 2003267145 A AU2003267145 A AU 2003267145A AU 2003267145 A1 AU2003267145 A1 AU 2003267145A1
Authority
AU
Australia
Prior art keywords
gtpases
highly specific
target validation
specific modulators
modulators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003267145A
Other languages
English (en)
Other versions
AU2003267145A8 (en
Inventor
Maria A. Cuento
Kavita Shah
Fabien Vincent
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IRM LLC
Novartis Pharmaceuticals Corp
Original Assignee
IRM LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IRM LLC filed Critical IRM LLC
Publication of AU2003267145A1 publication Critical patent/AU2003267145A1/en
Publication of AU2003267145A8 publication Critical patent/AU2003267145A8/xx
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
AU2003267145A 2002-09-13 2003-09-10 Highly specific modulators of gtpases for target validation Abandoned AU2003267145A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41053602P 2002-09-13 2002-09-13
US60/410,536 2002-09-13
US46175503P 2003-04-09 2003-04-09
US60/461,755 2003-04-09
PCT/US2003/028594 WO2004024082A2 (fr) 2002-09-13 2003-09-10 Modulateurs hautement specifiques de gtpases pour validation de cibles

Publications (2)

Publication Number Publication Date
AU2003267145A1 true AU2003267145A1 (en) 2004-04-30
AU2003267145A8 AU2003267145A8 (en) 2004-04-30

Family

ID=31997959

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003267145A Abandoned AU2003267145A1 (en) 2002-09-13 2003-09-10 Highly specific modulators of gtpases for target validation

Country Status (3)

Country Link
US (1) US20040241706A1 (fr)
AU (1) AU2003267145A1 (fr)
WO (1) WO2004024082A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060079493A1 (en) * 2001-03-01 2006-04-13 Lawrence Fritz Methods for treating genetically- defined proliferative disorders with hsp90 inhibitors
EP2145888A1 (fr) 2003-09-18 2010-01-20 Conforma Therapeutics Corporation Dérivés de déazapurine en tant qu'inhibiteurs de l'HSP90
BRPI0609509A2 (pt) * 2005-03-30 2010-04-13 Conforma Therapeutics Corp composto ou um polimorfo, solvato, tautÈmero, enanciÈmero, pró-droga ou sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso do composto, polimorfo, solvato, tautÈmero, enanciÈmero, pró-droga ou sal farmaceuticamente aceitável
WO2007035963A2 (fr) * 2005-09-23 2007-03-29 Conforma Therapeutics Corporation Methodes antitumorales dans lesquelles sont utilises des inhibiteurs de hsp90 de synthese independants de la multiresistance aux medicaments
US20070191371A1 (en) * 2006-02-14 2007-08-16 Kalypsys, Inc. Heterocyclic modulators of ppar
US7678894B2 (en) * 2007-05-18 2010-03-16 Helicos Biosciences Corporation Nucleotide analogs
US9163053B2 (en) 2007-05-18 2015-10-20 Fluidigm Corporation Nucleotide analogs
EP2970360A4 (fr) * 2013-03-13 2017-02-22 Dana-Farber Cancer Institute, Inc. Inhibiteurs de ras et leurs utilisations
CN103204857A (zh) * 2013-05-08 2013-07-17 兰州聚成生物科技有限公司 一种4-氯-2-(甲硫基)-7h-吡咯并[2,3-d]嘧啶的合成方法
US20170017750A1 (en) * 2015-02-03 2017-01-19 Nantomics, Llc High Throughput Patient Genomic Sequencing And Clinical Reporting Systems
WO2016192083A1 (fr) * 2015-06-04 2016-12-08 Merck Sharp & Dohme Corp. Composés dihydropyrazolopyrimidinone utilisés en tant qu'en tant qu'inhibiteurs de pde2
CN110337437B (zh) 2016-12-28 2023-02-03 达特神经科学有限公司 作为pde2抑制剂的取代的吡唑并嘧啶酮化合物
KR102794907B1 (ko) 2017-11-27 2025-04-14 다트 뉴로사이언스, 엘엘씨 Pde1 억제제로서의 치환된 푸라노피리미딘 화합물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2279846C (fr) * 1997-02-07 2008-06-03 Princeton University Proteines kinases manipulees capables d'utiliser des substrats a triphosphate nucleotidique modifies

Also Published As

Publication number Publication date
US20040241706A1 (en) 2004-12-02
AU2003267145A8 (en) 2004-04-30
WO2004024082A2 (fr) 2004-03-25
WO2004024082A3 (fr) 2009-06-18

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase