[go: up one dir, main page]

AU2003263301A1 - Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate - Google Patents

Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate

Info

Publication number
AU2003263301A1
AU2003263301A1 AU2003263301A AU2003263301A AU2003263301A1 AU 2003263301 A1 AU2003263301 A1 AU 2003263301A1 AU 2003263301 A AU2003263301 A AU 2003263301A AU 2003263301 A AU2003263301 A AU 2003263301A AU 2003263301 A1 AU2003263301 A1 AU 2003263301A1
Authority
AU
Australia
Prior art keywords
morphine
preparation
tartrate
alternative processes
alternative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003263301A
Other versions
AU2003263301A8 (en
Inventor
Paul Mather
John Whittall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stylacats Ltd
Original Assignee
Stylacats Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stylacats Ltd filed Critical Stylacats Ltd
Publication of AU2003263301A8 publication Critical patent/AU2003263301A8/en
Publication of AU2003263301A1 publication Critical patent/AU2003263301A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003263301A 2002-09-03 2003-09-03 Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate Abandoned AU2003263301A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0220385.9 2002-09-03
GB0220385A GB2392670A (en) 2002-09-03 2002-09-03 (+)-Morphine production
PCT/GB2003/003805 WO2004022564A2 (en) 2002-09-03 2003-09-03 Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate

Publications (2)

Publication Number Publication Date
AU2003263301A8 AU2003263301A8 (en) 2004-03-29
AU2003263301A1 true AU2003263301A1 (en) 2004-03-29

Family

ID=9943367

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003263301A Abandoned AU2003263301A1 (en) 2002-09-03 2003-09-03 Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate

Country Status (3)

Country Link
AU (1) AU2003263301A1 (en)
GB (1) GB2392670A (en)
WO (1) WO2004022564A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006019246D1 (en) 2005-06-16 2011-02-10 Mallinckrodt Inc SYNTHETIC ROUTE TO 14-HYDROXYLOPIATES OVER 1-HALOGENHEBINE OR ANALOG
JP2010533719A (en) * 2007-07-17 2010-10-28 マリンクロッド・インコーポレイテッド Preparation of N-alkylated opiates by reductive amination
US8252928B2 (en) 2008-09-16 2012-08-28 Mallinckrodt LLC. Processes for the synthesis of five and six membered heterocyclic rings
NZ593198A (en) * 2008-12-02 2013-02-22 Mallinckrodt Llc Process for preparing hydrocodone comprising a super acid-assisted furan ring closure reaction
US8946419B2 (en) 2009-02-23 2015-02-03 Mallinckrodt Llc (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
WO2010096791A1 (en) * 2009-02-23 2010-08-26 Mallinckrodt Inc. (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
US8563727B2 (en) * 2009-02-23 2013-10-22 Mallinckrodt Llc (+)-morphinanium N-oxides and processes for their production
US10363251B2 (en) 2009-07-16 2019-07-30 Mallinckrodt Llc (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
WO2011009015A1 (en) * 2009-07-16 2011-01-20 Mallinckrodt Inc. (+) - morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
EP2593095B1 (en) 2010-07-16 2019-03-27 Mallinckrodt LLC (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
CN104672142B (en) * 2015-02-13 2017-08-04 江苏大学 Preparation and medical application of binary structure sinomenine derivatives
CN109666030B (en) * 2018-11-19 2021-04-27 兰州大学 A method for catalyzing asymmetric synthesis of codeine and morphine
WO2021195209A1 (en) * 2020-03-24 2021-09-30 University Of Padova Morphinan isomers and their structural modifications as nmdar antagonists and neuroplastogens

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1495271A (en) * 1974-04-10 1977-12-14 Macfarlan Smith Ltd Dehydrohalogenation of codeinone derivatives
CA2063607C (en) * 1989-08-17 2001-08-07 Patricia A. Broderick Microelectrodes and their use in cathodic electrochemical current arrangement with telemetric application

Also Published As

Publication number Publication date
AU2003263301A8 (en) 2004-03-29
WO2004022564A3 (en) 2004-07-01
GB0220385D0 (en) 2002-10-09
GB2392670A (en) 2004-03-10
WO2004022564A2 (en) 2004-03-18

Similar Documents

Publication Publication Date Title
AU2003248721A1 (en) Adsorbents, methods of preparation, and methods of use thereof
AU2003233010A1 (en) Process for the preparation of 3,3,4,4-tetrafluoropyrrolidine and derivatives thereof
AU2002348135A1 (en) Methods for the treatment of addiction
AU2003262747A1 (en) Compounds, compositions, and methods
AU2003236527A1 (en) Compounds, compositions, and methods
AU2003265242A1 (en) Compounds, compositions, and methods
AU2003270015A1 (en) Compounds, compositions, and methods
AU2003301066A1 (en) Al2o3-la2o3-y2o3-mgo ceramics, and methods of making the same
AU2003274211A1 (en) Flame-retardant composition, preparation method and use thereof
AU2003299612A1 (en) Compounds, compositions and methods
AU2003239614A1 (en) Cardiolipin compositions, methods of preparation and use
AU2003231352A1 (en) Biocidal formulation and methods for the preparation thereof
AU2003277079A1 (en) Compounds, compositions, and methods
AU2003207199A1 (en) Structure, method of manufacturing the same, and device using the same
AU2003263301A1 (en) Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate
AU2002341511A1 (en) Macroporous gel, its preparation and its use
AU2003296369A1 (en) Imminoamines and preparation thereof
AU2003290507A1 (en) Compounds, compositions and methods
EP1670894B8 (en) Compositions including different types of transfer factor, methods for making the compositions, and methods of treatment using the compositions
AU2002362589A1 (en) Basecoat composition and application methods therewith
AU2003260983A1 (en) Processes for the preparation of s-(-)-amlodipine
AU2002367890A1 (en) Process for the preparation of 4-methyl-thiazole-5-carbaldehyde intermediate
AU2003220026A1 (en) Methods and compositions for the treatment of ischemia
AU2003267169A1 (en) Compounds, compositions and methods
AU2003300031A1 (en) Compounds, compositions, and methods

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase