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AU2003260291A1 - Proximity-aided synthesis of templated molecules - Google Patents

Proximity-aided synthesis of templated molecules

Info

Publication number
AU2003260291A1
AU2003260291A1 AU2003260291A AU2003260291A AU2003260291A1 AU 2003260291 A1 AU2003260291 A1 AU 2003260291A1 AU 2003260291 A AU2003260291 A AU 2003260291A AU 2003260291 A AU2003260291 A AU 2003260291A AU 2003260291 A1 AU2003260291 A1 AU 2003260291A1
Authority
AU
Australia
Prior art keywords
proximity
templated molecules
aided synthesis
aided
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003260291A
Other versions
AU2003260291A8 (en
Inventor
Thomas Franch
Thomas Thisted
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuevolution AS
Original Assignee
Nuevolution AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuevolution AS filed Critical Nuevolution AS
Publication of AU2003260291A1 publication Critical patent/AU2003260291A1/en
Publication of AU2003260291A8 publication Critical patent/AU2003260291A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Wind Motors (AREA)
AU2003260291A 2002-09-12 2003-09-12 Proximity-aided synthesis of templated molecules Abandoned AU2003260291A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US40996802P 2002-09-12 2002-09-12
US60/409,968 2002-09-12
DKPA200201347 2002-09-12
DKPA200201347 2002-09-12
PCT/DK2003/000590 WO2004024929A2 (en) 2002-09-12 2003-09-12 Proximity-aided synthesis of templated molecules

Publications (2)

Publication Number Publication Date
AU2003260291A1 true AU2003260291A1 (en) 2004-04-30
AU2003260291A8 AU2003260291A8 (en) 2004-04-30

Family

ID=31995414

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003260291A Abandoned AU2003260291A1 (en) 2002-09-12 2003-09-12 Proximity-aided synthesis of templated molecules

Country Status (3)

Country Link
EP (1) EP1539953A2 (en)
AU (1) AU2003260291A1 (en)
WO (1) WO2004024929A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1423400E (en) 2001-03-19 2006-12-29 Harvard College Evolving new molecular function
US7727713B2 (en) 2001-06-20 2010-06-01 Nuevolution A/S Templated molecules and methods for using such molecules
NZ535144A (en) 2002-03-15 2006-03-31 Nuevolution As An improved method for synthesising templated molecules
US10730906B2 (en) 2002-08-01 2020-08-04 Nuevolutions A/S Multi-step synthesis of templated molecules
US7491494B2 (en) 2002-08-19 2009-02-17 President And Fellows Of Harvard College Evolving new molecular function
PT1558744E (en) * 2002-10-30 2011-09-22 Nuevolution As Enzymatic encoding
AU2011226815B2 (en) * 2002-10-30 2014-09-25 Nuevolution A/S Enzymatic encoding
DE60330406D1 (en) 2002-12-19 2010-01-14 Nuevolution As THROUGH QUASIZATIONAL STRUCTURES AND FUNCTIONS OF SYNTHESIS METHOD
EP1597395A2 (en) 2003-02-21 2005-11-23 Nuevolution A/S Method for producing second-generation library
DE602004019764D1 (en) 2003-03-20 2009-04-16 Nuevolution As LIGATION-RELATED CODING OF SMALL MOLECULES
DK1670939T3 (en) * 2003-09-18 2010-03-01 Nuevolution As Method for obtaining structural information on a coded molecule and method for selecting compounds
US7972994B2 (en) 2003-12-17 2011-07-05 Glaxosmithkline Llc Methods for synthesis of encoded libraries
EP2366705A1 (en) 2003-12-17 2011-09-21 Praecis Pharmaceuticals Incorporated Methods for synthesis of encoded libraries
DE602005017370D1 (en) 2004-03-22 2009-12-10 Nuevolution As LIGATION CODING USING OLIGONUCLEOTIDE COMPONENTS
DE602005012139D1 (en) 2004-11-08 2009-02-12 Vipergen Aps STRUCTURAL NUCLEIC ACID-LED CHEMICAL SYNTHESIS
ATE462005T1 (en) 2005-06-17 2010-04-15 Harvard College ITERATED BRANCHING PATHWAYS VIA NUCLEIC ACID-MEDIATED CHEMISTRY
CA2626325A1 (en) 2005-10-28 2007-05-10 Praecis Pharmaceuticals Incorporated Methods for identifying compounds of interest using encoded libraries
DK2336315T3 (en) 2005-12-01 2017-11-06 Nuevolution As Method for enzymatic coding by efficient synthesis of large libraries
AP3396A (en) 2009-02-13 2015-08-31 Chem Inc X Methods of creating and screening DNA-encoded libraries
US11225655B2 (en) 2010-04-16 2022-01-18 Nuevolution A/S Bi-functional complexes and methods for making and using such complexes
BR112014005205A2 (en) 2011-09-07 2017-03-21 X-Chem Inc methods for tagging dna encoded libraries
SG10201907347YA (en) 2012-07-13 2019-09-27 X Chem Inc Dna-encoded libraries having encoding oligonucleotide linkages not readable by polymerases
EP3532613A4 (en) * 2016-10-26 2020-05-06 ModernaTX, Inc. METHODS AND COMPOSITIONS FOR RNA MAPPING
US12215377B2 (en) 2018-09-07 2025-02-04 The J. David Gladstone Institute, a testamentary trust established under the Will of J. David Gladstone HIV or HCV detection with CRISPR-CAS13A
US12460259B2 (en) 2019-03-11 2025-11-04 Modernatx, Inc. Fed-batch in vitro transcription process

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573905A (en) * 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US7479472B1 (en) * 1998-10-19 2009-01-20 The Board Of Trustees Of The Leland Stanford Junior University DNA-templated combinatorial library chemistry
PT1423400E (en) * 2001-03-19 2006-12-29 Harvard College Evolving new molecular function
NZ535144A (en) * 2002-03-15 2006-03-31 Nuevolution As An improved method for synthesising templated molecules

Also Published As

Publication number Publication date
WO2004024929A2 (en) 2004-03-25
EP1539953A2 (en) 2005-06-15
WO2004024929A3 (en) 2004-05-06
AU2003260291A8 (en) 2004-04-30

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase