AU2003257982A8 - Pharmaceutical dosage form capable of maintaining stable dissolution profile upon storage - Google Patents

Pharmaceutical dosage form capable of maintaining stable dissolution profile upon storage

Info

Publication number: AU2003257982A8
Authority: AU; Australia
Prior art keywords: storage; dosage form; pharmaceutical dosage; dissolution profile; form capable
Prior art date: 2002-07-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

AU2003257982A

Other versions

AU2003257982A1 (en

Inventor

Ping Gao

Xiaorong He

Juliane M Bauer

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pharmacia LLC

Original Assignee

Pharmacia LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-31

Filing date

2003-07-31

Publication date

2004-02-16

2003-07-31 Application filed by Pharmacia LLC filed Critical Pharmacia LLC

2004-02-16 Publication of AU2003257982A8 publication Critical patent/AU2003257982A8/en

2004-02-16 Publication of AU2003257982A1 publication Critical patent/AU2003257982A1/en

Status Abandoned legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Neurosurgery (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Physical Education & Sports Medicine (AREA)
Reproductive Health (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Addiction (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Tropical Medicine & Parasitology (AREA)
Gastroenterology & Hepatology (AREA)
Ophthalmology & Optometry (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)

AU2003257982A 2002-07-31 2003-07-31 Pharmaceutical dosage form capable of maintaining stable dissolution profile upon storage Abandoned AU2003257982A1 (en)

Applications Claiming Priority (9)

Application Number	Priority Date	Filing Date	Title
US39986202P	2002-07-31	2002-07-31
US39986302P	2002-07-31	2002-07-31
US39977602P	2002-07-31	2002-07-31
US39980802P	2002-07-31	2002-07-31
US60/399,862		2002-07-31
US60/399,776		2002-07-31
US60/399,863		2002-07-31
US60/399,808		2002-07-31
PCT/US2003/024043 WO2004010973A2 (en)	2002-07-31	2003-07-31	Pharmaceutical dosage form capable of maintaining stable dissolution profile upon storage

Publications (2)

Publication Number	Publication Date
AU2003257982A8 true AU2003257982A8 (en)	2004-02-16
AU2003257982A1 AU2003257982A1 (en)	2004-02-16

Family

ID=31192378

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
AU2003257102A Abandoned AU2003257102A1 (en)	2002-07-31	2003-07-31	Pharmaceutical dosage form comprising a sulfite compound
AU2003257982A Abandoned AU2003257982A1 (en)	2002-07-31	2003-07-31	Pharmaceutical dosage form capable of maintaining stable dissolution profile upon storage
AU2003257981A Abandoned AU2003257981A1 (en)	2002-07-31	2003-07-31	Pellicle-resistant gelatin capsule
AU2003257103A Abandoned AU2003257103A1 (en)	2002-07-31	2003-07-31	Gelatin capsule exhibiting reduced cross-linking

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AU2003257102A Abandoned AU2003257102A1 (en)	2002-07-31	2003-07-31	Pharmaceutical dosage form comprising a sulfite compound

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AU2003257981A Abandoned AU2003257981A1 (en)	2002-07-31	2003-07-31	Pellicle-resistant gelatin capsule
AU2003257103A Abandoned AU2003257103A1 (en)	2002-07-31	2003-07-31	Gelatin capsule exhibiting reduced cross-linking

Country Status (7)

Country	Link
EP (4)	EP1526846A2 (en)
JP (4)	JP2005538102A (en)
AU (4)	AU2003257102A1 (en)
BR (4)	BR0313150A (en)
CA (4)	CA2493980A1 (en)
MX (4)	MXPA05000862A (en)
WO (4)	WO2004010972A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003103582A2 (en)	2002-06-05	2003-12-18	Ivax Corporation	Reduction of gelatin cross-linking
CN101142198B (en)	2005-02-17	2012-10-31	辛塔制药公司	Isoxazole cambrestatin derivatives for use in the treatment of diseases
US7485323B2 (en)	2005-05-31	2009-02-03	Gelita Ag	Process for making a low molecular weight gelatine hydrolysate and gelatine hydrolysate compositions
ATE485033T1 (en) *	2005-07-26	2010-11-15	Nicox Sa	PHARMACEUTICAL FORMULATION OF NITROOXY DERIVATIVES OF NSAIDS
JP5503939B2 (en) *	2009-10-16	2014-05-28	東洋カプセル株式会社	Azelastine hydrochloride-containing capsule
JP6887456B2 (en)	2018-07-04	2021-06-16	キャプシュゲル・ベルジウム・エヌ・ヴィ	A film-forming composition containing a surfactant or a surfactant and a salt as a whitening agent.
US11364478B2 (en) *	2019-05-22	2022-06-21	Mezzimatic, LLC	Method of manufacturing throwable paintballs and paintballs made therefrom
KR20220077091A (en) *	2020-12-01	2022-06-08	주식회사 엘지화학	Composite formulation for oral administration comprising 1-(3-cyano-1-isopropyl-indol-5-yl)pyrazol-4-carboxyl acid and a process for the preparation thereof
CN113230241A (en) *	2021-06-11	2021-08-10	北京畅盛医药科技有限公司	Application of tris (hydroxymethyl) aminomethane salt in medicine for treating cardiovascular and cerebrovascular diseases

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5115094B2 (en) *	1972-11-01	1976-05-14
US4349529A (en) *	1980-04-14	1982-09-14	E. R. Squibb & Sons, Inc.	Diagnostic and therapeutic capsules and method of producing
US4590183A (en) *	1985-04-22	1986-05-20	Sterling Drug Inc.	Gastric cytoprotection with sodium thiosulfate in oral administration of aspirin
FR2617047B1 (en) *	1987-06-23	1991-05-10	Sanofi Sa	TANNING RESISTANT GELATIN COMPOSITION, CAPSULES BASED ON THIS COMPOSITION AND THEIR PHARMACEUTICAL APPLICATION, IN PARTICULAR TO FENOFIBRATE
JP2790659B2 (en) *	1989-06-30	1998-08-27	帝国臓器製薬株式会社	Gelatin capsule
KR100338851B1 (en) *	1994-03-15	2002-10-12	센주 세이야꾸 가부시키가이샤	How to stabilize pranopropene and stable pranopropene
IT1269583B (en) *	1994-04-26	1997-04-08	Bayer Italia Spa	PHARMACEUTICAL PREPARATIONS BASED ON A SOLUTION OF KETOPROFENE IN SOFT GELATINE CAPSULES AND METHOD FOR THEIR PRODUCTION
DK0695544T3 (en) *	1994-08-05	2001-01-02	Shionogi & Co	Hard gelatin capsules that can withstand denaturation and methods of making them
US5620704A (en) *	1994-11-07	1997-04-15	Warner-Lambert Company	Process for stabilizing gelatin products
US7115565B2 (en) *	2001-01-18	2006-10-03	Pharmacia & Upjohn Company	Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability

2003
- 2003-07-31 BR BR0313150-5A patent/BR0313150A/en not_active IP Right Cessation
- 2003-07-31 EP EP03772161A patent/EP1526846A2/en not_active Withdrawn
- 2003-07-31 JP JP2004524263A patent/JP2005538102A/en not_active Abandoned
- 2003-07-31 EP EP03772160A patent/EP1526845A2/en not_active Withdrawn
- 2003-07-31 MX MXPA05000862A patent/MXPA05000862A/en not_active Application Discontinuation
- 2003-07-31 JP JP2004524262A patent/JP2005538994A/en not_active Withdrawn
- 2003-07-31 MX MXPA05001272A patent/MXPA05001272A/en unknown
- 2003-07-31 CA CA002493980A patent/CA2493980A1/en not_active Abandoned
- 2003-07-31 MX MXPA05001167A patent/MXPA05001167A/en unknown
- 2003-07-31 JP JP2004534259A patent/JP2006500389A/en not_active Withdrawn
- 2003-07-31 AU AU2003257102A patent/AU2003257102A1/en not_active Abandoned
- 2003-07-31 WO PCT/US2003/024042 patent/WO2004010972A2/en not_active Ceased
- 2003-07-31 CA CA002493974A patent/CA2493974A1/en not_active Abandoned
- 2003-07-31 JP JP2004524261A patent/JP2005538993A/en not_active Withdrawn
- 2003-07-31 CA CA002494069A patent/CA2494069A1/en not_active Abandoned
- 2003-07-31 WO PCT/US2003/024045 patent/WO2004010974A2/en not_active Ceased
- 2003-07-31 EP EP03794452A patent/EP1526847A2/en not_active Withdrawn
- 2003-07-31 WO PCT/US2003/024043 patent/WO2004010973A2/en not_active Ceased
- 2003-07-31 AU AU2003257982A patent/AU2003257982A1/en not_active Abandoned
- 2003-07-31 WO PCT/US2003/024044 patent/WO2004022032A2/en not_active Ceased
- 2003-07-31 BR BR0313064-9A patent/BR0313064A/en not_active IP Right Cessation
- 2003-07-31 MX MXPA05001166A patent/MXPA05001166A/en unknown
- 2003-07-31 BR BR0313149-1A patent/BR0313149A/en not_active IP Right Cessation
- 2003-07-31 BR BR0312875-0A patent/BR0312875A/en not_active IP Right Cessation
- 2003-07-31 CA CA002494358A patent/CA2494358A1/en not_active Abandoned
- 2003-07-31 AU AU2003257981A patent/AU2003257981A1/en not_active Abandoned
- 2003-07-31 EP EP03772159A patent/EP1526844A2/en not_active Withdrawn
- 2003-07-31 AU AU2003257103A patent/AU2003257103A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU2003257981A8 (en)	2004-02-16
JP2005538993A (en)	2005-12-22
WO2004010972A3 (en)	2004-07-29
WO2004022032A3 (en)	2004-08-12
AU2003257102A8 (en)	2004-03-29
CA2494358A1 (en)	2004-02-05
AU2003257102A1 (en)	2004-03-29
JP2006500389A (en)	2006-01-05
AU2003257981A1 (en)	2004-02-16
JP2005538994A (en)	2005-12-22
BR0313064A (en)	2005-06-28
BR0313150A (en)	2005-06-28
WO2004022032A2 (en)	2004-03-18
MXPA05001166A (en)	2005-05-16
EP1526844A2 (en)	2005-05-04
AU2003257103A8 (en)	2004-02-16
WO2004010972A2 (en)	2004-02-05
EP1526846A2 (en)	2005-05-04
EP1526845A2 (en)	2005-05-04
WO2004010973A3 (en)	2004-08-05
JP2005538102A (en)	2005-12-15
MXPA05001272A (en)	2005-04-28
WO2004010973A2 (en)	2004-02-05
BR0312875A (en)	2005-06-28
CA2494069A1 (en)	2004-02-05
WO2004010974A2 (en)	2004-02-05
WO2004010974A3 (en)	2004-08-05
CA2493980A1 (en)	2004-02-05
BR0313149A (en)	2005-06-28
EP1526847A2 (en)	2005-05-04
MXPA05001167A (en)	2005-05-16
AU2003257103A1 (en)	2004-02-16
AU2003257982A1 (en)	2004-02-16
MXPA05000862A (en)	2005-04-19
CA2493974A1 (en)	2004-03-18

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Date	Code	Title	Description
2005-05-19	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase