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AU2003252149A1 - Thiophene and furan derivatives as prostaglandin agonists and use thereof - Google Patents

Thiophene and furan derivatives as prostaglandin agonists and use thereof

Info

Publication number
AU2003252149A1
AU2003252149A1 AU2003252149A AU2003252149A AU2003252149A1 AU 2003252149 A1 AU2003252149 A1 AU 2003252149A1 AU 2003252149 A AU2003252149 A AU 2003252149A AU 2003252149 A AU2003252149 A AU 2003252149A AU 2003252149 A1 AU2003252149 A1 AU 2003252149A1
Authority
AU
Australia
Prior art keywords
thiophene
furan derivatives
prostaglandin agonists
prostaglandin
agonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003252149A
Other versions
AU2003252149A8 (en
Inventor
Gian Luca Araldi
Srinivasa Karra
Yihua Liao
Adulla P. Reddy
Zhong Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Research Systems ARS Holding NV
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Publication of AU2003252149A1 publication Critical patent/AU2003252149A1/en
Publication of AU2003252149A8 publication Critical patent/AU2003252149A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003252149A 2002-08-02 2003-07-25 Thiophene and furan derivatives as prostaglandin agonists and use thereof Abandoned AU2003252149A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40065402P 2002-08-02 2002-08-02
US60/400,654 2002-08-02
PCT/US2003/023165 WO2004012656A2 (en) 2002-08-02 2003-07-25 Thiophene and furan derivatives as prostaglandin agonists and use thereof

Publications (2)

Publication Number Publication Date
AU2003252149A1 true AU2003252149A1 (en) 2004-02-23
AU2003252149A8 AU2003252149A8 (en) 2004-02-23

Family

ID=31495849

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003252149A Abandoned AU2003252149A1 (en) 2002-08-02 2003-07-25 Thiophene and furan derivatives as prostaglandin agonists and use thereof

Country Status (2)

Country Link
AU (1) AU2003252149A1 (en)
WO (1) WO2004012656A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2373187C2 (en) * 2003-06-24 2009-11-20 Ф.Хоффманн-Ля Рош Аг Biaryloxymethylarene carboxylic acids
US7355049B2 (en) 2003-06-24 2008-04-08 Hoffmann-La Roche Inc. Biaryloxymethylarenecarboxylic acids as glycogen synthase activator
EP1723132A1 (en) 2004-02-12 2006-11-22 Asterand Uk Limited Ep2 receptor agonists
US7524870B2 (en) * 2004-12-03 2009-04-28 Hoffmann-La Roche Inc. Biaryloxymethylarenecarboxylic acids as glycogen synthase activators
CA2618486A1 (en) * 2005-08-09 2007-02-15 Asterand Uk Limited Ep2 receptor agonists
WO2008058766A1 (en) 2006-11-16 2008-05-22 Bayer Schering Pharma Aktiengesellschaft Ep2 and ep4 agonists as agents for the treatment of influenza a viral infection
EP2098226A1 (en) * 2008-03-06 2009-09-09 Forschungsverbund Berlin e.V. AKAP-PKA interaction inhibitors for use in the treatment of heart diseases
EP2149551A1 (en) 2008-07-30 2010-02-03 Bayer Schering Pharma AG N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors
EP2149554A1 (en) 2008-07-30 2010-02-03 Bayer Schering Pharma Aktiengesellschaft Indolyamides as modulators for an EP2 receptor
EP2149552A1 (en) 2008-07-30 2010-02-03 Bayer Schering Pharma AG 5,6 substituted benzamide derivatives as modulators of EP2 receptors
WO2012018980A2 (en) * 2010-08-04 2012-02-09 Yun Michael Shim Compositions and methods for treating inflammatory diseases
ES2481346B1 (en) * 2012-12-26 2015-05-08 Consejo Superior De Investigaciones Científicas (Csic) PROCEDURE FOR OBTAINING USEFUL ORGANIC MOLECULES AS NEW SURFACTING AGENTS.
CN113149941A (en) * 2020-01-22 2021-07-23 中国科学院上海药物研究所 Ether compound and pharmaceutical application thereof in preventing and treating diabetes and metabolic syndrome

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023272A (en) * 1989-06-23 1991-06-11 Norwich Eaton Pharmaceuticals, Inc. Use of 5-phenyl-2-furan esters and amides as antiepileptic agents

Also Published As

Publication number Publication date
WO2004012656A3 (en) 2004-07-01
WO2004012656A2 (en) 2004-02-12
AU2003252149A8 (en) 2004-02-23

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