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AU2002339423A1 - Organo-phosphorous compounds for activating gamma/delta T cells - Google Patents

Organo-phosphorous compounds for activating gamma/delta T cells

Info

Publication number
AU2002339423A1
AU2002339423A1 AU2002339423A AU2002339423A AU2002339423A1 AU 2002339423 A1 AU2002339423 A1 AU 2002339423A1 AU 2002339423 A AU2002339423 A AU 2002339423A AU 2002339423 A AU2002339423 A AU 2002339423A AU 2002339423 A1 AU2002339423 A1 AU 2002339423A1
Authority
AU
Australia
Prior art keywords
organo
delta
cells
phosphorous compounds
activating gamma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002339423A
Other versions
AU2002339423B2 (en
AU2002339423C1 (en
Inventor
Boran Altincicek
Mathias Eberl
Martin Hintz
Hassan Jomaa
Ann-Kristin Kollas
Armin Reichenberg
Jochen Wiesner
Oliver Wolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioagency AG
Original Assignee
Bioagency AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2001134705 external-priority patent/DE10134705A1/en
Priority claimed from DE2001135395 external-priority patent/DE10135395A1/en
Application filed by Bioagency AG filed Critical Bioagency AG
Priority claimed from PCT/EP2002/007986 external-priority patent/WO2003009855A2/en
Application granted granted Critical
Publication of AU2002339423C1 publication Critical patent/AU2002339423C1/en
Publication of AU2002339423A1 publication Critical patent/AU2002339423A1/en
Publication of AU2002339423B2 publication Critical patent/AU2002339423B2/en
Priority to AU2007202803A priority Critical patent/AU2007202803B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002339423A 2001-07-20 2002-07-18 Organo-phosphorous compounds for activating gamma/delta T cells Ceased AU2002339423B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2007202803A AU2007202803B2 (en) 2001-07-20 2007-06-15 Organo-phosphorous compounds for activating gamma/delta T cells

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE2001134705 DE10134705A1 (en) 2001-07-20 2001-07-20 New acyclic or cyclic organophosphorus compounds, are gamma-delta-T cell activators useful e.g. as medicaments for treating asthma, chronic bronchitis, ulcerative colitis, autoimmune diseases or allergies
DE10134705.7 2001-07-20
DE2001135395 DE10135395A1 (en) 2001-07-25 2001-07-25 New acyclic or cyclic organophosphorus compounds, are gamma-delta-T cell activators useful e.g. as medicaments for treating asthma, chronic bronchitis, ulcerative colitis, autoimmune diseases or allergies
DE10135395.2 2001-07-25
PCT/EP2002/007986 WO2003009855A2 (en) 2001-07-20 2002-07-18 Organo-phosphorous compounds for activating gamma/delta t cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2007202803A Division AU2007202803B2 (en) 2001-07-20 2007-06-15 Organo-phosphorous compounds for activating gamma/delta T cells

Publications (3)

Publication Number Publication Date
AU2002339423C1 AU2002339423C1 (en) 2003-02-17
AU2002339423A1 true AU2002339423A1 (en) 2003-05-29
AU2002339423B2 AU2002339423B2 (en) 2007-03-15

Family

ID=26009714

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002339423A Ceased AU2002339423B2 (en) 2001-07-20 2002-07-18 Organo-phosphorous compounds for activating gamma/delta T cells

Country Status (13)

Country Link
US (3) US7399756B2 (en)
EP (1) EP1408984B1 (en)
JP (1) JP4607451B2 (en)
KR (1) KR100906018B1 (en)
CN (1) CN1533279A (en)
AT (1) ATE411805T1 (en)
AU (1) AU2002339423B2 (en)
CA (1) CA2453817C (en)
DE (1) DE50212935D1 (en)
DK (1) DK1408984T3 (en)
ES (1) ES2315411T3 (en)
PT (1) PT1408984E (en)
WO (1) WO2003009855A2 (en)

Families Citing this family (35)

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DE10201458A1 (en) * 2001-04-11 2002-10-17 Adelbert Bacher New proteins involved in isoprenoid biosynthesis, useful in screening for inhibitors, also new intermediates, potential therapeutic agents, nucleic acids and antibodies
CA2453817C (en) * 2001-07-20 2011-09-20 Bioagency Ag Organophosphorus compounds for the activation of gamma/delta t-cells
FR2833266B1 (en) * 2001-12-11 2004-10-22 Mayoly Spindler Lab NOVEL PHOSPHONATE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR USE AS MODULATORS OF THE ACTIVITY OF TGAMMA9 DELTA2 LYMPHOCYTES
FR2836483B1 (en) * 2002-02-22 2006-09-15 Innate Pharma METHODS FOR PRODUCING GAMMA DELTA T LYMPHOCYTES
GB0212666D0 (en) * 2002-05-31 2002-07-10 Secr Defence Immunogenic sequences
DE60233576D1 (en) * 2002-12-02 2009-10-15 Innate Pharma Interleukin-2 and gamma Delta T cell activator containing compositions and their uses
AU2004233898B2 (en) * 2003-04-25 2010-12-23 Gilead Sciences, Inc. Antiviral phosphonate analogs
EP1689758A2 (en) * 2003-12-02 2006-08-16 Innate Pharma New class of gamma delta t cells activators and use thereof
US20100291118A1 (en) * 2003-12-02 2010-11-18 Innate Pharma Class of Gamma Delta T Cells Activators and Use Thereof
US20070134273A1 (en) * 2004-02-10 2007-06-14 Francois Romagne Composition and method for the treatment of carcinoma
WO2005102385A1 (en) 2004-04-26 2005-11-03 Innate Pharma Adjuvant composition and methods for its use
ES2363160T3 (en) 2004-07-27 2011-07-22 Gilead Sciences, Inc. NUCELOSIDIC PHOSPHONATE CONJUGATES AS ANTI-HIV AGENTS.
WO2006067635A2 (en) * 2004-12-20 2006-06-29 Innate Pharma S.A. USE OF Ϝδ T LYMPHOCYTE ACTIVATORS AS VACCINE ADJUVANT
EP1863572A2 (en) * 2005-03-22 2007-12-12 Innate Pharma New class of t cells activators and use thereof
GB2443591B (en) * 2005-09-07 2010-04-28 Secr Defence Adjuvanted vaccine
JP2009511449A (en) * 2005-10-06 2009-03-19 イナート・ファルマ Phosphorylated antigen salt of organic base and crystallization method thereof
WO2008012538A2 (en) 2006-07-25 2008-01-31 The Secretary Of State For Defence Live vaccine strains of francisella
EP2083830A1 (en) 2006-11-17 2009-08-05 Innate Pharma Improved methods of using phosphoantigen for the treatment of cancer
EP2123285A1 (en) 2008-05-21 2009-11-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Nucleosidic phosphoantigens for use in VGAMMA9DELTA2 T cell-mediated therapy
JP5620376B2 (en) 2008-07-08 2014-11-05 ギリアード サイエンシーズ, インコーポレイテッド Salts of HIV inhibitor compounds
EP2324040B1 (en) 2008-09-10 2014-01-01 Innate Pharma Novel polymorphic form of chdmapp, method of preparation thereof, and pharmaceutical composition comprising same
GB0901423D0 (en) * 2009-01-29 2009-03-11 Secr Defence Treatment
GB0901411D0 (en) * 2009-01-29 2009-03-11 Secr Defence Treatment
GB0906234D0 (en) 2009-04-14 2009-05-20 Secr Defence Vaccine
US10814006B2 (en) 2015-07-14 2020-10-27 University Of Iowa Research Foundation Fluorescent prodrugs
ES2892402T3 (en) 2017-08-01 2022-02-04 Gilead Sciences Inc Crystal forms of ((S)-((((2R,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl)oxy)methyl Ethyl)(phenoxy)phosphoryl)-L-alaninate to treat viral infections
CN109651429A (en) * 2017-10-11 2019-04-19 清华大学 The small molecule agonist of 2 T cell of V γ 9V δ of efficient stable
EP3723701B1 (en) 2017-12-11 2025-08-06 The Procter & Gamble Company Method of making phosphono-phosphate containing compounds
CN111465383A (en) 2017-12-11 2020-07-28 宝洁公司 Oral care compositions comprising polymers containing phosphonate groups and anionic groups
US11046798B2 (en) 2017-12-11 2021-06-29 The Procter & Gamble Company Phosphono-phosphate containing compounds and polymers
US11198763B2 (en) 2017-12-11 2021-12-14 The Procter & Gamble Company Oral care compositions comprising phosphono-phosphate and anionic group containing polymers
EP3723867A1 (en) 2017-12-11 2020-10-21 The Procter & Gamble Company Phosphono-phosphate and anionic group containing polymers
US11046817B2 (en) 2017-12-11 2021-06-29 The Procter & Gamble Company Compositions comprising multi-valent cations and phosphono-phosphate containing polymers
WO2019182904A1 (en) 2018-03-19 2019-09-26 University Of Iowa Research Foundation Phosphonamidate butyrophilin ligands
EP3856206A1 (en) 2018-09-27 2021-08-04 Phosphogam, Inc. Methods and compositions for the expansion and use of allogeneic gamma/delta-t cells

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639653A (en) * 1993-07-19 1997-06-17 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva Universtiy Method for proliferating Vγ2Vδ2 T cells
FR2715660A1 (en) 1994-01-28 1995-08-04 Centre Nat Rech Scient Organophosphorus activating compounds of Tgammadelta lymphocytes, process for preparing and / or isolating and / or characterizing these compounds, compositions and pharmaceutical uses.
EP0952834A2 (en) * 1996-05-15 1999-11-03 The University of Sheffield Isopentenyl pyrophosphate isomerase (ipi) and/or prenyl transferase inhibitors
DE19828450A1 (en) 1998-06-26 1999-12-30 Hassan Jomaa Use of bisphosphonic acid compounds and autoantigens or allergens
FR2782721B1 (en) 1998-09-01 2000-11-03 Inst Nat Sante Rech Med NOVEL PHOSPHOHALOHYDRIN COMPOUNDS, MANUFACTURING METHOD AND APPLICATIONS
CA2343919A1 (en) * 1998-09-22 2000-03-30 Hassan Jomaa Genes of the 1-desoxy-d-xylulose biosynthetic pathway
DE19854310A1 (en) 1998-11-25 2000-06-29 Hassan Jomaa Use of phosphonoformic acid derivatives for the therapeutic and prophylactic treatment of infections
WO2000043403A1 (en) * 1999-01-21 2000-07-27 Chugai Seiyaku Kabushiki Kaisha 2-methyl-3-butenyl-1-pyrophosphoric acid salts and agents for treating lymphocytes
FR2791981B1 (en) * 1999-04-06 2001-07-20 Inst Nat Sante Rech Med COMPOUNDS SELECTIVELY INHIBITING LYMPHOCYTES TGAMMA9DELTA2, AND APPLICATIONS THEREOF
WO2000072022A1 (en) * 1999-05-21 2000-11-30 Jomaa Pharmaka Gmbh Use of genes of the deoxy-d-xylulose phosphate biosynthetic pathway for altering the concentration of isoprenoid
WO2001022816A1 (en) 1999-09-30 2001-04-05 National Jewish Medical And Research Center MODULATION OF ηδ T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS
DE10027821A1 (en) 2000-06-05 2001-12-06 Adelbert Bacher New intermediate in isoprenoid biosynthesis, useful in screening for potential herbicides, comprises mutant encoding-enzymes sequences for imparting herbicide resistance
AU9052201A (en) 2000-08-07 2002-02-18 Monsanto Technology Llc Methyl-d-erythritol phosphate pathway genes
DE10201458A1 (en) * 2001-04-11 2002-10-17 Adelbert Bacher New proteins involved in isoprenoid biosynthesis, useful in screening for inhibitors, also new intermediates, potential therapeutic agents, nucleic acids and antibodies
DE10119905A1 (en) 2001-04-23 2002-10-24 Jomaa Pharmaka Gmbh Enriching intermediates in the mevalonate-independent pathway of isoprenoid synthesis, useful for therapeutic activation of T cells, comprises altering enzymatic activity in the pathway
CA2453817C (en) * 2001-07-20 2011-09-20 Bioagency Ag Organophosphorus compounds for the activation of gamma/delta t-cells
WO2003038072A1 (en) 2001-10-31 2003-05-08 Universite Libre De Bruxelles Generation and use of new types of dendritic cells

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