AU2002323873A1 - Active ingredient combination of E.G. galanthamine or deoxypeganine and E.G. acamprosate or memantine for treating an addiction such as alcoholism - Google Patents

Active ingredient combination of E.G. galanthamine or deoxypeganine and E.G. acamprosate or memantine for treating an addiction such as alcoholism

Info

Publication number: AU2002323873A1
Authority: AU; Australia
Prior art keywords: deoxypeganine; acamprosate; galanthamine; memantine; alcoholism
Prior art date: 2001-06-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU2002323873A

Other versions

AU2002323873B2 (en

Inventor

Joachim Moormann

Hermann Mucke

Klaus Opitz

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

HF Arzneimittelforschung GmbH and Co KG

Original Assignee

HF Arzneimittelforschung GmbH and Co KG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-18

Filing date

2002-06-15

Publication date

2003-05-15

2001-06-18 Priority claimed from DE10129265A external-priority patent/DE10129265A1/en

2002-06-15 Application filed by HF Arzneimittelforschung GmbH and Co KG filed Critical HF Arzneimittelforschung GmbH and Co KG

2003-05-15 Publication of AU2002323873A1 publication Critical patent/AU2002323873A1/en

2006-11-16 Application granted granted Critical

2006-11-16 Publication of AU2002323873B2 publication Critical patent/AU2002323873B2/en

2022-06-15 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

WUFQLZTXIWKION-UHFFFAOYSA-N Deoxypeganine Chemical compound C1C2=CC=CC=C2N=C2N1CCC2 WUFQLZTXIWKION-UHFFFAOYSA-N 0.000 title 2
ASUTZQLVASHGKV-JDFRZJQESA-N galanthamine Chemical compound O1C(=C23)C(OC)=CC=C2CN(C)CC[C@]23[C@@H]1C[C@@H](O)C=C2 ASUTZQLVASHGKV-JDFRZJQESA-N 0.000 title 2
HPOIPOPJGBKXIR-UHFFFAOYSA-N 3,6-dimethoxy-10-methyl-galantham-1-ene Natural products O1C(C(=CC=2)OC)=C3C=2CN(C)CCC23C1CC(OC)C=C2 HPOIPOPJGBKXIR-UHFFFAOYSA-N 0.000 title 1
208000007848 Alcoholism Diseases 0.000 title 1
LPCKPBWOSNVCEL-UHFFFAOYSA-N Chlidanthine Natural products O1C(C(=CC=2)O)=C3C=2CN(C)CCC23C1CC(OC)C=C2 LPCKPBWOSNVCEL-UHFFFAOYSA-N 0.000 title 1
VARHXCYGZKSOOO-UHFFFAOYSA-N Deoxyvasicinone Natural products C1=CC=C2C(=O)N(CCC3)C3=NC2=C1 VARHXCYGZKSOOO-UHFFFAOYSA-N 0.000 title 1
206010012335 Dependence Diseases 0.000 title 1
AFCGFAGUEYAMAO-UHFFFAOYSA-N acamprosate Chemical compound CC(=O)NCCCS(O)(=O)=O AFCGFAGUEYAMAO-UHFFFAOYSA-N 0.000 title 1
229960004047 acamprosate Drugs 0.000 title 1
239000004480 active ingredient Substances 0.000 title 1
201000007930 alcohol dependence Diseases 0.000 title 1
229960003980 galantamine Drugs 0.000 title 1
BGLNUNCBNALFOZ-WMLDXEAASA-N galanthamine Natural products COc1ccc2CCCC[C@@]34C=CCC[C@@H]3Oc1c24 BGLNUNCBNALFOZ-WMLDXEAASA-N 0.000 title 1
ASUTZQLVASHGKV-UHFFFAOYSA-N galanthamine hydrochloride Natural products O1C(=C23)C(OC)=CC=C2CN(C)CCC23C1CC(O)C=C2 ASUTZQLVASHGKV-UHFFFAOYSA-N 0.000 title 1
IYVSXSLYJLAZAT-NOLJZWGESA-N lycoramine Natural products CN1CC[C@@]23CC[C@H](O)C[C@@H]2Oc4cccc(C1)c34 IYVSXSLYJLAZAT-NOLJZWGESA-N 0.000 title 1
BUGYDGFZZOZRHP-UHFFFAOYSA-N memantine Chemical compound C1C(C2)CC3(C)CC1(C)CC2(N)C3 BUGYDGFZZOZRHP-UHFFFAOYSA-N 0.000 title 1
229960004640 memantine Drugs 0.000 title 1

AU2002323873A 2001-06-18 2002-06-15 Active ingredient combination of E.G. galanthamine or deoxypeganine and E.G. acamprosate or memantine for treating an addiction such as alcoholism Ceased AU2002323873B2 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE10129265A DE10129265A1 (en)	2001-06-18	2001-06-18	Active ingredient combination for drug addiction or intoxicant therapy
DE10129265.1		2001-06-18
PCT/EP2002/006630 WO2002102388A2 (en)	2001-06-18	2002-06-15	Active ingredient combination of e.g. galanthamine or deoxypeganine and e.g. acamprosate or memantine for treating an addiction such as alcoholism

Publications (2)

Publication Number	Publication Date
AU2002323873A1 true AU2002323873A1 (en)	2003-05-15
AU2002323873B2 AU2002323873B2 (en)	2006-11-16

Family

ID=7688529

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2002323873A Ceased AU2002323873B2 (en)	2001-06-18	2002-06-15	Active ingredient combination of E.G. galanthamine or deoxypeganine and E.G. acamprosate or memantine for treating an addiction such as alcoholism

Country Status (27)

Country	Link
US (1)	US20040192683A1 (en)
EP (1)	EP1397138B1 (en)
JP (1)	JP2005500298A (en)
KR (1)	KR20040010744A (en)
CN (1)	CN1527711A (en)
AR (1)	AR034493A1 (en)
AT (1)	ATE286397T1 (en)
AU (1)	AU2002323873B2 (en)
BR (1)	BR0211008A (en)
CA (1)	CA2450787C (en)
CZ (1)	CZ299951B6 (en)
DE (2)	DE10129265A1 (en)
EA (1)	EA006647B1 (en)
ES (1)	ES2236551T3 (en)
HU (1)	HUP0400865A3 (en)
IL (2)	IL159345A0 (en)
MX (1)	MXPA03011825A (en)
MY (1)	MY129726A (en)
NO (1)	NO20035458D0 (en)
NZ (1)	NZ529944A (en)
PL (1)	PL367207A1 (en)
PT (1)	PT1397138E (en)
SK (1)	SK287180B6 (en)
TW (1)	TWI325320B (en)
UA (1)	UA76753C2 (en)
WO (1)	WO2002102388A2 (en)
ZA (1)	ZA200309232B (en)

Families Citing this family (18)

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DE10134038A1 (en) *	2001-07-12	2003-02-06	Hf Arzneimittelforsch Gmbh	Active ingredient combination for drug therapy of nicotine addiction
DE10318714B4 (en) *	2003-04-25	2006-03-23	Hf Arzneimittelforschung Gmbh	Drug combinations and therapies to combat alcohol abuse
DE10354894A1 (en) *	2003-11-24	2005-07-07	Hf Arzneimittelforschung Gmbh	Oral formulations of deoxypeganine and their applications
DE102004048927A1 (en) *	2004-10-06	2006-04-20	Lts Lohmann Therapie-Systeme Ag	Pharmaceutical combination containing deoxypeganine and Cyp2D6 inhibitors
US7619007B2 (en)	2004-11-23	2009-11-17	Adamas Pharmaceuticals, Inc.	Method and composition for administering an NMDA receptor antagonist to a subject
BRPI0607017B8 (en)	2005-04-06	2021-05-25	Adamas Pharmaceuticals Inc	pharmaceutical composition comprising memantine and donezepil, and their use for the treatment of snc-related conditions
PT1895994E (en) *	2005-05-13	2010-12-03	Alza Corp	Multilayer drug delivery system with barrier against reservoir material flow
WO2007026841A1 (en)	2005-09-01	2007-03-08	Mitsubishi Chemical Corporation	Apparatus for heat treatment of polyester particle and method of multistage solid-phase polycondensation of polyester particle
US20070104771A1 (en) *	2005-09-23	2007-05-10	Jay Audett	Transdermal galantamine delivery system
US9463172B2 (en)	2009-02-12	2016-10-11	Indiana University Research & Technology Corporation	Material and methods for treating developmental disorders including comorbid and idiopathic autism
CN106389381A (en)	2009-12-02	2017-02-15	阿达玛斯医药公司	Amantadine compositions and methods of use
CA2850468C (en)	2010-09-28	2019-08-13	Depomed, Inc.	Gastric retentive dosage forms for extended release of acamprosate into the upper gastrointestinal tract
PL3884947T3 (en) *	2010-12-03	2024-05-06	Nalpropion Pharmaceuticals Llc	Increasing drug bioavailability in naltrexone therapy
WO2013160728A1 (en)	2012-04-26	2013-10-31	Alma Mater Studiorum - Universita' Di Bologna	Dual targeting compounds for the treatment of alzheimer's disease
US10154971B2 (en)	2013-06-17	2018-12-18	Adamas Pharma, Llc	Methods of administering amantadine
CN108210486B (en) *	2016-12-14	2020-05-19	陆汝斌	Use of composition for preparing medicine for treating alcohol addiction or alcohol abuse
AU2018320946B2 (en)	2017-08-24	2024-05-02	Adamas Pharma, Llc	Amantadine compositions, preparations thereof, and methods of use
BG67408B1 (en) *	2019-04-12	2022-01-17	Софарма Ад	Oral drug composition with plant alkaloid for treatment of addictions

Family Cites Families (19)

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US3797494A (en) *	1969-04-01	1974-03-19	Alza Corp	Bandage for the administration of drug by controlled metering through microporous materials
US3996934A (en) *	1971-08-09	1976-12-14	Alza Corporation	Medical bandage
US3742951A (en) *	1971-08-09	1973-07-03	Alza Corp	Bandage for controlled release of vasodilators
US4031894A (en) *	1975-12-08	1977-06-28	Alza Corporation	Bandage for transdermally administering scopolamine to prevent nausea
DE3315272C2 (en) *	1983-04-27	1986-03-27	Lohmann Gmbh & Co Kg, 5450 Neuwied	Pharmaceutical product and process for its manufacture
DE3843239C1 (en) *	1988-12-22	1990-02-22	Lohmann Therapie Syst Lts
EP0424179A3 (en) *	1989-10-20	1991-12-27	John William Olney	Use of combined excitatory amino acid and cholinergic antagonists to prevent neurological deterioration
DE4010079A1 (en) *	1990-03-29	1991-10-02	Lohmann Therapie Syst Lts	PHARMACEUTICAL FORMULATION FOR THE TREATMENT OF ALCOHOLISM
US5519017A (en) *	1990-03-29	1996-05-21	Lts Lohmann Therapie-Systeme Gmbh + Co. Kg	Pharmaceutic formulation for the treatment of alcoholism
US5668117A (en) *	1991-02-22	1997-09-16	Shapiro; Howard K.	Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments
PL184590B1 (en) *	1994-10-21	2002-11-29	Sanochemia Pharmazeutika Ag	A method for producing derivatives of hexahydro H benzofuro [a ef] [] benzazepines, a method for debromination of these derivatives, a method for producing N-type compounds, demethylbromo and epibromo-galantamine, and new compounds from a specific set
DE19509663A1 (en) *	1995-03-17	1996-09-19	Lohmann Therapie Syst Lts	Process for the isolation of galanthamine
GB9514821D0 (en) *	1995-07-19	1995-09-20	Sod Conseils Rech Applic	Galanthamine derivatives
AT403803B (en) *	1996-04-19	1998-05-25	Sanochemia Ltd	NEW BENZAZEPINE DERIVATIVES, THESE MEDICINAL PRODUCTS AND THE USE THEREOF FOR THE PRODUCTION OF MEDICINAL PRODUCTS
EP0945133A1 (en) *	1998-03-26	1999-09-29	Lipha	Combination for the treatment of alcohol and drug dependence containing an opioid antagonist and a NMDA receptor complex modulator
WO1999054280A1 (en) *	1998-04-17	1999-10-28	Kenneth Curry	Cubane derivatives as metabotropic glutamate receptor antagonists and process for their preparation
DE19906974C2 (en) *	1999-02-19	2003-10-09	Lohmann Therapie Syst Lts	Use of deoxypeganine for the treatment of alcoholism
DE19906978B4 (en) *	1999-02-19	2004-07-08	Lts Lohmann Therapie-Systeme Ag	Pharmaceutical composition containing deoxypeganine for the treatment of drug dependence
DE19906979B4 (en) *	1999-02-19	2004-07-08	Lts Lohmann Therapie-Systeme Ag	Use of deoxypeganine for the treatment of nicotine addiction

2001
- 2001-06-18 DE DE10129265A patent/DE10129265A1/en not_active Withdrawn
2002
- 2002-06-14 AR ARP020102244A patent/AR034493A1/en unknown
- 2002-06-15 BR BR0211008-3A patent/BR0211008A/en not_active Application Discontinuation
- 2002-06-15 AU AU2002323873A patent/AU2002323873B2/en not_active Ceased
- 2002-06-15 DE DE50201958T patent/DE50201958D1/en not_active Expired - Lifetime
- 2002-06-15 PT PT02754688T patent/PT1397138E/en unknown
- 2002-06-15 AT AT02754688T patent/ATE286397T1/en not_active IP Right Cessation
- 2002-06-15 KR KR10-2003-7016570A patent/KR20040010744A/en not_active Ceased
- 2002-06-15 CZ CZ20033390A patent/CZ299951B6/en not_active IP Right Cessation
- 2002-06-15 MX MXPA03011825A patent/MXPA03011825A/en active IP Right Grant
- 2002-06-15 US US10/480,287 patent/US20040192683A1/en not_active Abandoned
- 2002-06-15 UA UA20031211802A patent/UA76753C2/en unknown
- 2002-06-15 JP JP2003504974A patent/JP2005500298A/en active Pending
- 2002-06-15 HU HU0400865A patent/HUP0400865A3/en unknown
- 2002-06-15 CA CA002450787A patent/CA2450787C/en not_active Expired - Fee Related
- 2002-06-15 CN CNA028110196A patent/CN1527711A/en active Pending
- 2002-06-15 SK SK1565-2003A patent/SK287180B6/en not_active IP Right Cessation
- 2002-06-15 WO PCT/EP2002/006630 patent/WO2002102388A2/en not_active Ceased
- 2002-06-15 NZ NZ529944A patent/NZ529944A/en unknown
- 2002-06-15 ES ES02754688T patent/ES2236551T3/en not_active Expired - Lifetime
- 2002-06-15 EA EA200400041A patent/EA006647B1/en not_active IP Right Cessation
- 2002-06-15 EP EP02754688A patent/EP1397138B1/en not_active Expired - Lifetime
- 2002-06-15 PL PL02367207A patent/PL367207A1/en unknown
- 2002-06-15 IL IL15934502A patent/IL159345A0/en active IP Right Grant
- 2002-06-17 MY MYPI20022245A patent/MY129726A/en unknown
- 2002-06-17 TW TW091113176A patent/TWI325320B/en not_active IP Right Cessation
2003
- 2003-11-27 ZA ZA200309232A patent/ZA200309232B/en unknown
- 2003-12-08 NO NO20035458A patent/NO20035458D0/en not_active Application Discontinuation
- 2003-12-11 IL IL159345A patent/IL159345A/en not_active IP Right Cessation

Publication	Publication Date	Title
AU2002323873A1 (en)	2003-05-15	Active ingredient combination of E.G. galanthamine or deoxypeganine and E.G. acamprosate or memantine for treating an addiction such as alcoholism
WO2001098236A3 (en)	2002-03-28	7-phenyl-substituted tetracycline compounds
MXPA03008710A (en)	2003-12-11	Compositions and methods of zearalenone detoxification.
AU2002345970A1 (en)	2003-01-21	Stabilized compositions and processes of their preparation
AU2001272189A1 (en)	2003-05-22	Configuration of implanted devices
WO2002102388A3 (en)	2003-09-18	Active ingredient combination of e.g. galanthamine or deoxypeganine and e.g. acamprosate or memantine for treating an addiction such as alcoholism
ZA200204019B (en)	2003-11-21	Combination treatment for alcoholism and alcohol dependence.
AU2002231206A1 (en)	2002-07-01	Treatment of depression
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