|
EP1631676A4
(en)
*
|
2003-06-10 |
2006-12-20 |
Toolgen Inc |
Transducible dna-binding proteins
|
|
US20120196370A1
(en)
|
2010-12-03 |
2012-08-02 |
Fyodor Urnov |
Methods and compositions for targeted genomic deletion
|
|
US7888121B2
(en)
|
2003-08-08 |
2011-02-15 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted cleavage and recombination
|
|
WO2005014791A2
(en)
|
2003-08-08 |
2005-02-17 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted cleavage and recombination
|
|
EP1678315B1
(en)
|
2003-09-19 |
2011-08-03 |
Sangamo BioSciences, Inc. |
Engineered zinc finger proteins for regulation of gene expression
|
|
CA2544214C
(en)
|
2003-11-05 |
2018-08-28 |
International Institute Of Cancer Immunology, Inc. |
Hla-dr-binding antigen peptide derived from wt1
|
|
DE102005026163A1
(en)
*
|
2004-08-24 |
2006-03-02 |
Dade Behring Marburg Gmbh |
Antibodies directed against the Marburg I polymorphism of Factor VII activating protease (FSAP), their production and use
|
|
CA2579677A1
(en)
|
2004-09-16 |
2006-03-30 |
Sangamo Biosciences, Inc. |
Compositions and methods for protein production
|
|
US20090263900A1
(en)
|
2008-04-14 |
2009-10-22 |
Sangamo Biosciences, Inc. |
Linear donor constructs for targeted integration
|
|
KR101419729B1
(en)
|
2005-07-26 |
2014-07-17 |
상가모 바이오사이언스 인코포레이티드 |
Targeted integration and expression of exogenous nucleic acid sequences
|
|
CA2651494C
(en)
|
2006-05-25 |
2015-09-29 |
Sangamo Biosciences, Inc. |
Engineered cleavage half-domains
|
|
AU2007267874B2
(en)
|
2006-05-25 |
2012-03-15 |
Sangamo Therapeutics, Inc. |
Methods and compositions for gene inactivation
|
|
JP2010500029A
(en)
|
2006-08-11 |
2010-01-07 |
ダウ アグロサイエンシィズ エルエルシー |
Zinc finger nuclease-mediated homologous recombination
|
|
AU2007319881B2
(en)
*
|
2006-11-13 |
2012-05-17 |
Sangamo Therapeutics, Inc. |
Zinc finger nuclease for targeting the human glucocorticoid receptor locus
|
|
JP5632610B2
(en)
|
2006-12-14 |
2014-11-26 |
ダウ アグロサイエンシィズ エルエルシー |
Optimized non-canonical zinc finger protein
|
|
EP2119778B1
(en)
|
2007-02-27 |
2015-11-04 |
International Institute of Cancer Immunology, Inc. |
Method for activation of helper T cell and composition for use in the method
|
|
AU2008244473B2
(en)
|
2007-04-26 |
2013-06-20 |
Sangamo Therapeutics, Inc. |
Targeted integration into the PPP1R12C locus
|
|
CA2691440A1
(en)
|
2007-06-29 |
2009-01-08 |
Pioneer Hi-Bred International, Inc. |
Methods for altering the genome of a monocot plant cell
|
|
WO2009009086A2
(en)
|
2007-07-12 |
2009-01-15 |
Sangamo Biosciences, Inc. |
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (fut 8) gene expression
|
|
EP2188384B1
(en)
|
2007-09-27 |
2015-07-15 |
Sangamo BioSciences, Inc. |
Rapid in vivo identification of biologically active nucleases
|
|
US8563314B2
(en)
|
2007-09-27 |
2013-10-22 |
Sangamo Biosciences, Inc. |
Methods and compositions for modulating PD1
|
|
CA2937438C
(en)
|
2007-09-27 |
2020-07-07 |
Dow Agrosciences Llc |
Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
|
|
US11235026B2
(en)
|
2007-09-27 |
2022-02-01 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modulating PD1
|
|
WO2009054985A1
(en)
|
2007-10-25 |
2009-04-30 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted integration
|
|
US9394531B2
(en)
|
2008-05-28 |
2016-07-19 |
Sangamo Biosciences, Inc. |
Compositions for linking DNA-binding domains and cleavage domains
|
|
EP2130836B1
(en)
*
|
2008-06-03 |
2013-02-13 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Means and methods for producing zinc fingers and concatemers thereof
|
|
KR101802393B1
(en)
|
2008-06-10 |
2017-11-28 |
상가모 테라퓨틱스, 인코포레이티드 |
Methods and compositions for generation of bax- and bak-deficient cell lines
|
|
EP2789691B1
(en)
|
2008-08-22 |
2018-08-08 |
Sangamo Therapeutics, Inc. |
Methods and compositions for targeted single-stranded cleavage and targeted integration
|
|
JP5756016B2
(en)
|
2008-10-29 |
2015-07-29 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
Method and composition for inactivating expression of glutamine synthetase gene
|
|
ES2627552T3
(en)
|
2008-12-04 |
2017-07-28 |
Sigma Aldrich Company |
Genome editing in rats using zinc finger nucleases
|
|
KR101683928B1
(en)
|
2008-12-17 |
2016-12-07 |
다우 아그로사이언시즈 엘엘씨 |
Targeted integration into the Zp15 locus
|
|
US8551945B2
(en)
|
2009-02-04 |
2013-10-08 |
Sangamo Biosciences, Inc. |
Methods and compositions for treating neuropathies
|
|
EP2408921B1
(en)
|
2009-03-20 |
2017-04-19 |
Sangamo BioSciences, Inc. |
Modification of cxcr4 using engineered zinc finger proteins
|
|
JP6215533B2
(en)
|
2009-04-09 |
2017-10-18 |
サンガモ セラピューティクス, インコーポレイテッド |
Targeted integration into stem cells
|
|
US8772008B2
(en)
|
2009-05-18 |
2014-07-08 |
Sangamo Biosciences, Inc. |
Methods and compositions for increasing nuclease activity
|
|
CA2765488C
(en)
|
2009-06-30 |
2018-01-02 |
Sangamo Biosciences, Inc. |
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
|
|
US9234016B2
(en)
|
2009-07-28 |
2016-01-12 |
Sangamo Biosciences, Inc. |
Engineered zinc finger proteins for treating trinucleotide repeat disorders
|
|
JP5940977B2
(en)
|
2009-08-11 |
2016-06-29 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
Homozygous organisms by targeted modification
|
|
BR122019025207B1
(en)
|
2009-10-22 |
2022-10-04 |
Sangamo Biosciences, Inc. |
NON-NATURALLY OCCURRING ZINC FINGER PROTEIN AND FUSION PROTEIN
|
|
US8956828B2
(en)
|
2009-11-10 |
2015-02-17 |
Sangamo Biosciences, Inc. |
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
|
|
AU2010339481B2
(en)
|
2009-12-30 |
2016-02-04 |
Pioneer Hi-Bred International, Inc. |
Methods and compositions for targeted polynucleotide modification
|
|
WO2011090804A1
(en)
|
2010-01-22 |
2011-07-28 |
Dow Agrosciences Llc |
Targeted genomic alteration
|
|
ES2751916T3
(en)
|
2010-02-08 |
2020-04-02 |
Sangamo Therapeutics Inc |
Genomanipulated half-cleavages
|
|
EP2660318A1
(en)
|
2010-02-09 |
2013-11-06 |
Sangamo BioSciences, Inc. |
Targeted genomic modification with partially single-stranded donor molecules
|
|
SG185367A1
(en)
|
2010-04-26 |
2012-12-28 |
Sangamo Biosciences Inc |
Genome editing of a rosa locus using zinc-finger nucleases
|
|
WO2011139349A1
(en)
|
2010-05-03 |
2011-11-10 |
Sangamo Biosciences, Inc. |
Compositions for linking zinc finger modules
|
|
JP6208580B2
(en)
|
2010-05-17 |
2017-10-04 |
サンガモ セラピューティクス, インコーポレイテッド |
Novel DNA binding protein and use thereof
|
|
JP6050230B2
(en)
|
2010-07-21 |
2016-12-21 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
Methods and compositions for modification of HLA loci
|
|
EP2622090B1
(en)
|
2010-09-27 |
2019-06-19 |
Sangamo Therapeutics, Inc. |
Compositions for inhibiting viral entry into cells
|
|
EP2626418B8
(en)
|
2010-10-05 |
2021-03-24 |
International Institute of Cancer Immunology, Inc. |
Method for activating helper t cell
|
|
RU2608643C2
(en)
*
|
2010-10-12 |
2017-01-23 |
Дзе Чилдрен`З Хоспитал Оф Филадельфия |
Methods and compositions for treating hemophilia b
|
|
WO2012094132A1
(en)
|
2011-01-05 |
2012-07-12 |
Sangamo Biosciences, Inc. |
Methods and compositions for gene correction
|
|
WO2012098546A2
(en)
*
|
2011-01-20 |
2012-07-26 |
Oneday - Biotech And Pharma Ltd. |
Antioxidant, anti-inflammatory, anti-radiation, metal chelating compounds and uses thereof
|
|
BR112013024337A2
(en)
|
2011-03-23 |
2017-09-26 |
Du Pont |
complex transgenic trace locus in a plant, plant or seed, method for producing in a plant a complex transgenic trace locus and expression construct
|
|
SG194089A1
(en)
|
2011-04-27 |
2013-11-29 |
Amyris Inc |
Methods for genomic modification
|
|
WO2013066423A2
(en)
|
2011-06-21 |
2013-05-10 |
Pioneer Hi-Bred International, Inc. |
Methods and compositions for producing male sterile plants
|
|
US20140274812A1
(en)
|
2011-07-15 |
2014-09-18 |
The General Hospital Corporation |
Methods of Transcription Activator Like Effector Assembly
|
|
EP2737063B1
(en)
|
2011-07-25 |
2016-06-01 |
Sangamo BioSciences, Inc. |
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (cftr) gene
|
|
CA2848417C
(en)
|
2011-09-21 |
2023-05-02 |
Sangamo Biosciences, Inc. |
Methods and compositions for regulation of transgene expression
|
|
CA3099582A1
(en)
|
2011-10-27 |
2013-05-02 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of the hprt locus
|
|
HK1200871A1
(en)
|
2011-11-16 |
2015-08-14 |
Sangamo Therapeutics, Inc. |
Modified dna-binding proteins and uses thereof
|
|
EP2820159B1
(en)
|
2012-02-29 |
2019-10-23 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treating huntington's disease
|
|
HK1208052A1
(en)
|
2012-05-02 |
2016-02-19 |
陶氏益农公司 |
Targeted modification of malate dehydrogenase
|
|
WO2013169802A1
(en)
|
2012-05-07 |
2013-11-14 |
Sangamo Biosciences, Inc. |
Methods and compositions for nuclease-mediated targeted integration of transgenes
|
|
US9890364B2
(en)
|
2012-05-29 |
2018-02-13 |
The General Hospital Corporation |
TAL-Tet1 fusion proteins and methods of use thereof
|
|
ES2613691T3
(en)
|
2012-07-11 |
2017-05-25 |
Sangamo Biosciences, Inc. |
Methods and compositions for the treatment of lysosomal storage diseases
|
|
CA2878037C
(en)
|
2012-07-11 |
2021-08-31 |
Sangamo Biosciences, Inc. |
Methods and compositions for delivery of biologics
|
|
US10648001B2
(en)
|
2012-07-11 |
2020-05-12 |
Sangamo Therapeutics, Inc. |
Method of treating mucopolysaccharidosis type I or II
|
|
CN104717970A
(en)
|
2012-07-23 |
2015-06-17 |
万德-生物技术及制药有限公司 |
Compositions for increasing glutathione and uses thereof
|
|
EP2877194A4
(en)
|
2012-07-25 |
2016-03-16 |
Oneday Biotech And Pharma Ltd |
Compositions and methods for increasing carnitine level in muscle tissues
|
|
AU2013308770B2
(en)
|
2012-08-29 |
2019-01-17 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treatment of a genetic condition
|
|
UA118090C2
(en)
|
2012-09-07 |
2018-11-26 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Fad2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
|
|
UA119135C2
(en)
|
2012-09-07 |
2019-05-10 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Engineered transgene integration platform (etip) for gene targeting and trait stacking
|
|
AU2013312538B2
(en)
|
2012-09-07 |
2019-01-24 |
Corteva Agriscience Llc |
FAD3 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
|
|
EP3763810A3
(en)
|
2012-10-10 |
2021-07-14 |
Sangamo Therapeutics, Inc. |
T cell modifying compounds and uses thereof
|
|
EP2906602B1
(en)
|
2012-10-12 |
2019-01-16 |
The General Hospital Corporation |
Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins
|
|
JP2016500254A
(en)
|
2012-12-05 |
2016-01-12 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
Methods and compositions for the regulation of metabolic diseases
|
|
BR102013032200A2
(en)
|
2012-12-13 |
2015-11-24 |
Dow Agrosciences Llc |
precise targeting of a gene to a specific locus in maize
|
|
ES2805337T3
(en)
|
2012-12-17 |
2021-02-11 |
Otsuka Pharma Co Ltd |
Method to activate helper T cells
|
|
EP3623463B1
(en)
|
2013-02-07 |
2021-10-20 |
The General Hospital Corporation |
Tale transcriptional activators
|
|
EP2958996B1
(en)
|
2013-02-25 |
2019-10-16 |
Sangamo Therapeutics, Inc. |
Methods and compositions for enhancing nuclease-mediated gene disruption
|
|
US9937207B2
(en)
|
2013-03-21 |
2018-04-10 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell receptor genes using talens
|
|
WO2014165612A2
(en)
|
2013-04-05 |
2014-10-09 |
Dow Agrosciences Llc |
Methods and compositions for integration of an exogenous sequence within the genome of plants
|
|
AU2014262867B2
(en)
|
2013-05-10 |
2019-12-05 |
Sangamo Therapeutics, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering
|
|
HK1223401A1
(en)
|
2013-05-15 |
2017-07-28 |
桑格摩生物科学股份有限公司 |
Methods and compositions for treatment of a genetic condition
|
|
EP3591045B1
(en)
|
2013-08-28 |
2024-07-17 |
Sangamo Therapeutics, Inc. |
Compositions for linking dna-binding domains and cleavage domains
|
|
US10117899B2
(en)
|
2013-10-17 |
2018-11-06 |
Sangamo Therapeutics, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells
|
|
WO2015057980A1
(en)
|
2013-10-17 |
2015-04-23 |
Sangamo Biosciences, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering
|
|
WO2015066634A2
(en)
|
2013-11-04 |
2015-05-07 |
Dow Agrosciences Llc |
Optimal soybean loci
|
|
NZ735257A
(en)
|
2013-11-04 |
2018-09-28 |
Dow Agrosciences Llc |
Optimal soybean loci
|
|
JP6633532B2
(en)
|
2013-11-04 |
2020-01-22 |
ダウ アグロサイエンシィズ エルエルシー |
Optimal corn loci
|
|
WO2015066636A2
(en)
|
2013-11-04 |
2015-05-07 |
Dow Agrosciences Llc |
Optimal maize loci
|
|
US10369201B2
(en)
|
2013-11-11 |
2019-08-06 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treating Huntington's disease
|
|
HRP20211706T1
(en)
|
2013-11-13 |
2022-02-04 |
The Children's Medical Center Corporation |
Nuclease-mediated regulation of gene expression
|
|
CA2931848A1
(en)
|
2013-12-09 |
2015-06-18 |
Sangamo Biosciences, Inc. |
Methods and compositions for genome engineering
|
|
PT3083958T
(en)
|
2013-12-19 |
2019-06-27 |
Amyris Inc |
Methods for genomic integration
|
|
EP3110454B1
(en)
|
2014-02-24 |
2020-11-18 |
Sangamo Therapeutics, Inc. |
Methods and compositions for nuclease-mediated targeted integration
|
|
AU2015231353B2
(en)
|
2014-03-18 |
2020-11-05 |
Sangamo Therapeutics, Inc. |
Methods and compositions for regulation of zinc finger protein expression
|
|
WO2015164748A1
(en)
|
2014-04-24 |
2015-10-29 |
Sangamo Biosciences, Inc. |
Engineered transcription activator like effector (tale) proteins
|
|
AU2015255877B2
(en)
|
2014-05-08 |
2020-03-26 |
Chdi Foundation, Inc. |
Methods and compositions for treating huntington's disease
|
|
CA2947622A1
(en)
|
2014-05-13 |
2015-11-19 |
Sangamo Biosciences, Inc. |
Genome editing methods and compositions for prevention or treatment of a disease
|
|
US9970001B2
(en)
|
2014-06-05 |
2018-05-15 |
Sangamo Therapeutics, Inc. |
Methods and compositions for nuclease design
|
|
WO2016005449A1
(en)
|
2014-07-08 |
2016-01-14 |
Vib Vzw |
Means and methods to increase plant yield
|
|
AU2015289799B2
(en)
|
2014-07-14 |
2018-07-26 |
The University Court Of The University Of Edinburgh |
NANOS knock-out that ablates germline cells
|
|
US11278572B2
(en)
|
2014-07-18 |
2022-03-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Reducing CXCR4 expression and/or function to enhance engraftment of hematopoietic stem cells
|
|
US9816074B2
(en)
|
2014-07-25 |
2017-11-14 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells
|
|
WO2016014837A1
(en)
|
2014-07-25 |
2016-01-28 |
Sangamo Biosciences, Inc. |
Gene editing for hiv gene therapy
|
|
US9616090B2
(en)
|
2014-07-30 |
2017-04-11 |
Sangamo Biosciences, Inc. |
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells
|
|
KR20170054445A
(en)
|
2014-09-16 |
2017-05-17 |
상가모 테라퓨틱스, 인코포레이티드 |
Methods and compositions for nuclease-mediated genome engineering and correction in hematopoietic stem cells
|
|
US10889834B2
(en)
|
2014-12-15 |
2021-01-12 |
Sangamo Therapeutics, Inc. |
Methods and compositions for enhancing targeted transgene integration
|
|
US20180002379A1
(en)
|
2015-01-21 |
2018-01-04 |
Sangamo Therapeutics, Inc. |
Methods and compositions for identification of highly specific nucleases
|
|
US20180094243A1
(en)
|
2015-04-03 |
2018-04-05 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of genome editing of b-cells
|
|
US10179918B2
(en)
|
2015-05-07 |
2019-01-15 |
Sangamo Therapeutics, Inc. |
Methods and compositions for increasing transgene activity
|
|
MX382223B
(en)
|
2015-05-12 |
2025-03-13 |
Sangamo Therapeutics Inc |
NUCLEASE-MEDIATED REGULATION OF GENE EXPRESSION.
|
|
US9957501B2
(en)
|
2015-06-18 |
2018-05-01 |
Sangamo Therapeutics, Inc. |
Nuclease-mediated regulation of gene expression
|
|
CN108024544B
(en)
|
2015-07-13 |
2022-04-29 |
桑格摩生物治疗股份有限公司 |
Delivery methods and compositions for nuclease-mediated genome engineering
|
|
CN108025034B
(en)
*
|
2015-07-15 |
2022-09-30 |
新加坡科技研究局 |
Regulation of hepatitis b virus replication
|
|
SI3331355T1
(en)
|
2015-08-06 |
2024-10-30 |
The Curators Of The University Of Missouri |
Porcine reproductive and respiratory syndrome virus (prrsv)-resistant porcine and cells having modified cd163 genes
|
|
PT3352776T
(en)
|
2015-09-23 |
2025-06-27 |
Sangamo Therapeutics Inc |
HTT REPRESSORS AND THEIR USES
|
|
JP6976249B2
(en)
|
2015-11-23 |
2021-12-08 |
サンガモ セラピューティクス, インコーポレイテッド |
Methods and compositions for engineering immunity
|
|
WO2017106528A2
(en)
|
2015-12-18 |
2017-06-22 |
Sangamo Biosciences, Inc. |
Targeted disruption of the t cell receptor
|
|
WO2017106537A2
(en)
|
2015-12-18 |
2017-06-22 |
Sangamo Biosciences, Inc. |
Targeted disruption of the mhc cell receptor
|
|
EP3402533B1
(en)
|
2016-01-15 |
2021-08-04 |
Sangamo Therapeutics, Inc. |
Methods and compositions for the treatment of neurologic disease
|
|
EP3769775A3
(en)
|
2016-02-02 |
2021-03-17 |
Sangamo Therapeutics, Inc. |
Compositions for linking dna-binding domains and cleavage domains
|
|
US20190249172A1
(en)
|
2016-02-18 |
2019-08-15 |
The Regents Of The University Of California |
Methods and compositions for gene editing in stem cells
|
|
WO2017161043A1
(en)
|
2016-03-16 |
2017-09-21 |
The J. David Gladstone Institutes |
Methods and compositions for treating obesity and/or diabetes and for identifying candidate treatment agents
|
|
AU2017238512B2
(en)
|
2016-03-23 |
2022-12-08 |
Dana-Farber Cancer Institute, Inc. |
Methods for enhancing the efficiency of gene editing
|
|
US11293033B2
(en)
|
2016-05-18 |
2022-04-05 |
Amyris, Inc. |
Compositions and methods for genomic integration of nucleic acids into exogenous landing pads
|
|
EP4219462A1
(en)
|
2016-07-13 |
2023-08-02 |
Vertex Pharmaceuticals Incorporated |
Methods, compositions and kits for increasing genome editing efficiency
|
|
MA45793A
(en)
|
2016-07-27 |
2021-03-24 |
Univ Case Western Reserve |
MYELINATION STIMULATION COMPOUNDS AND METHODS
|
|
JP7066126B2
(en)
|
2016-08-09 |
2022-05-13 |
ブイアイビー ブイゼットダブリュ |
Cellulose synthase inhibitors and mutant plants
|
|
HRP20212025T1
(en)
|
2016-08-24 |
2022-04-01 |
Sangamo Therapeutics, Inc. |
Regulation of gene expression using engineered nucleases
|
|
WO2018039448A1
(en)
|
2016-08-24 |
2018-03-01 |
Sangamo Therapeutics, Inc. |
Engineered target specific nucleases
|
|
EP3509645A4
(en)
|
2016-09-07 |
2020-06-17 |
Sangamo Therapeutics, Inc. |
Modulation of liver genes
|
|
EP3757120B8
(en)
|
2016-10-04 |
2022-06-15 |
Precision Biosciences, Inc. |
Co-stimulatory domains for use in genetically-modified cells
|
|
MX2019004487A
(en)
|
2016-10-20 |
2020-02-07 |
Sangamo Therapeutics Inc |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF FABRY'S DISEASE.
|
|
CA3041668A1
(en)
|
2016-10-31 |
2018-05-03 |
Sangamo Therapeutics, Inc. |
Gene correction of scid-related genes in hematopoietic stem and progenitor cells
|
|
CA3043635A1
(en)
|
2016-12-01 |
2018-06-07 |
Sangamo Therapeutics, Inc. |
Tau modulators and methods and compositions for delivery thereof
|
|
WO2018106782A1
(en)
|
2016-12-08 |
2018-06-14 |
Case Western Reserve University |
Methods and compositions for enhancing functional myelin production
|
|
WO2018112282A1
(en)
|
2016-12-14 |
2018-06-21 |
Ligandal, Inc. |
Compositions and methods for nucleic acid and/or protein payload delivery
|
|
AU2018255975A1
(en)
|
2017-04-20 |
2019-08-15 |
Oregon Health & Science University |
Human gene correction
|
|
RU2019139045A
(en)
|
2017-05-03 |
2021-06-03 |
Сангамо Терапьютикс, Инк. |
METHODS AND COMPOSITIONS FOR MODIFICATION OF THE TRANSMEMBRANE CONDUCTIVITY REGULATOR GENE IN CYSTIC FIBROSIS (CFTR)
|
|
AU2018266698A1
(en)
|
2017-05-08 |
2019-11-28 |
Precision Biosciences, Inc. |
Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof
|
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
|
WO2019005957A1
(en)
|
2017-06-30 |
2019-01-03 |
Precision Biosciences, Inc. |
Genetically-modified t cells comprising a modified intron in the t cell receptor alpha gene
|
|
EP3692063A1
(en)
|
2017-10-03 |
2020-08-12 |
Juno Therapeutics, Inc. |
Hpv-specific binding molecules
|
|
US20200239544A1
(en)
|
2017-10-03 |
2020-07-30 |
Precision Biosciences, Inc. |
Modified epidermal growth factor receptor peptides for use in genetically-modified cells
|
|
WO2019089913A1
(en)
|
2017-11-01 |
2019-05-09 |
Precision Biosciences, Inc. |
Engineered nucleases that target human and canine factor viii genes as a treatment for hemophilia a
|
|
AU2018364660B2
(en)
|
2017-11-09 |
2022-05-19 |
Sangamo Therapeutics, Inc. |
Genetic modification of cytokine inducible SH2-containing protein (CISH) gene
|
|
JP7401432B2
(en)
|
2017-12-01 |
2023-12-19 |
エンコーデッド セラピューティクス, インコーポレイテッド |
engineered DNA binding protein
|
|
CA3084572A1
(en)
|
2017-12-18 |
2019-06-27 |
Syngenta Participations Ag |
Targeted insertion sites in the maize genome
|
|
IL276081B2
(en)
|
2018-01-17 |
2023-10-01 |
Vertex Pharma |
Quinoxalinone compounds, preparations, methods and kits for increasing the efficiency of genome editing
|
|
IL276080B2
(en)
|
2018-01-17 |
2023-10-01 |
Vertex Pharma |
DNA-PK suppressor compounds, UTP-containing preparations and their uses
|
|
KR20200109358A
(en)
|
2018-01-17 |
2020-09-22 |
버텍스 파마슈티칼스 인코포레이티드 |
DNA-PK inhibitor
|
|
BR112020015488A2
(en)
|
2018-02-08 |
2020-12-08 |
Sangamo Therapeutics, Inc. |
MODIFIED TARGET-SPECIFIC NUCLEASES
|
|
JP7589047B2
(en)
|
2018-04-05 |
2024-11-25 |
ジュノー セラピューティクス インコーポレイテッド |
Methods for producing cells expressing recombinant receptors and related compositions
|
|
WO2019195491A1
(en)
|
2018-04-05 |
2019-10-10 |
Juno Therapeutics, Inc. |
T cells expressing a recombinant receptor, related polynucleotides and methods
|
|
WO2019204457A1
(en)
|
2018-04-18 |
2019-10-24 |
Sangamo Therapeutics, Inc. |
Zinc finger protein compositions for modulation of huntingtin (htt)
|
|
US11690921B2
(en)
|
2018-05-18 |
2023-07-04 |
Sangamo Therapeutics, Inc. |
Delivery of target specific nucleases
|
|
CA3109592A1
(en)
|
2018-08-23 |
2020-02-27 |
Sangamo Therapeutics, Inc. |
Engineered target specific base editors
|
|
EP3853244A4
(en)
|
2018-09-18 |
2022-09-14 |
Sangamo Therapeutics, Inc. |
Programmed cell death 1 (pd1) specific nucleases
|
|
IL322436A
(en)
|
2018-09-21 |
2025-09-01 |
Acuitas Therapeutics Inc |
Systems and methods for manufacturing lipid nanoparticles and liposomes
|
|
KR20210070344A
(en)
|
2018-10-02 |
2021-06-14 |
상가모 테라퓨틱스, 인코포레이티드 |
Methods and compositions for modulation of tau protein
|
|
US20220090047A1
(en)
|
2018-12-21 |
2022-03-24 |
Precision Biosciences, Inc. |
Genetic modification of the hydroxyacid oxidase 1 gene for treatment of primary hyperoxaluria
|
|
WO2020146805A1
(en)
|
2019-01-11 |
2020-07-16 |
Acuitas Therapeutics, Inc. |
Lipids for lipid nanoparticle delivery of active agents
|
|
EP3826664A4
(en)
|
2019-02-06 |
2022-10-26 |
Sangamo Therapeutics, Inc. |
METHODS OF TREATMENT OF MUCOPOLYSACCHARIDOSIS TYPE I
|
|
WO2020163856A1
(en)
|
2019-02-10 |
2020-08-13 |
The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone |
Modified mitochondrion and methods of use thereof
|
|
CN113939586A
(en)
|
2019-04-02 |
2022-01-14 |
桑格摩生物治疗股份有限公司 |
Methods of treating beta-thalassemia
|
|
IL316764A
(en)
|
2019-04-03 |
2025-01-01 |
Prec Biosciences Inc |
Genetically-modified immune cells comprising a microrna-adapted shrna (shrnamir)
|
|
CA3136265A1
(en)
|
2019-04-05 |
2020-10-08 |
Precision Biosciences, Inc. |
Methods of preparing populations of genetically-modified immune cells
|
|
SG11202111443SA
(en)
|
2019-04-23 |
2021-11-29 |
Sangamo Therapeutics Inc |
Modulators of chromosome 9 open reading frame 72 gene expression and uses thereof
|
|
MX2021013223A
(en)
|
2019-05-01 |
2022-02-17 |
Juno Therapeutics Inc |
CELLS EXPRESSING A CHIMERIC RECEPTOR OF A MODIFIED CD247 LOCUS, RELATED POLYNUCLOTIDES AND METHODS.
|
|
CN114025788A
(en)
|
2019-05-01 |
2022-02-08 |
朱诺治疗学股份有限公司 |
Cells, related polynucleotides and methods for expressing recombinant receptors from modified TGFBR2 loci
|
|
EP4004216A1
(en)
|
2019-07-25 |
2022-06-01 |
Precision BioSciences, Inc. |
Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
|
|
WO2021035054A1
(en)
|
2019-08-20 |
2021-02-25 |
Precision Biosciences, Inc. |
Lymphodepletion dosing regimens for cellular immunotherapies
|
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
JP2022550608A
(en)
|
2019-10-02 |
2022-12-02 |
サンガモ セラピューティクス, インコーポレイテッド |
Zinc finger protein transcription factors for the treatment of prion diseases
|
|
AU2020356962A1
(en)
|
2019-10-02 |
2022-04-14 |
Sangamo Therapeutics, Inc. |
Zinc finger protein transcription factors for repressing alpha-synuclein expression
|
|
WO2021087305A1
(en)
|
2019-10-30 |
2021-05-06 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
|
EP4051787A1
(en)
|
2019-11-01 |
2022-09-07 |
Sangamo Therapeutics, Inc. |
Gin recombinase variants
|
|
WO2021113543A1
(en)
|
2019-12-06 |
2021-06-10 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy, using lymphodepletion regimens and cd19, cd20 or bcma allogeneic car t cells
|
|
JP2023511908A
(en)
|
2020-01-22 |
2023-03-23 |
サンガモ セラピューティクス, インコーポレイテッド |
A zinc finger protein transcription factor for tau repression
|
|
WO2021158915A1
(en)
|
2020-02-06 |
2021-08-12 |
Precision Biosciences, Inc. |
Recombinant adeno-associated virus compositions and methods for producing and using the same
|
|
WO2021188286A2
(en)
*
|
2020-02-28 |
2021-09-23 |
The Broad Institute, Inc. |
Zinc finger degradation domains
|
|
US20230263121A1
(en)
|
2020-03-31 |
2023-08-24 |
Elo Life Systems |
Modulation of endogenous mogroside pathway genes in watermelon and other cucurbits
|
|
CA3177093A1
(en)
|
2020-05-06 |
2021-11-11 |
Cellectis S.A. |
Methods for targeted insertion of exogenous sequences in cellular genomes
|
|
WO2021224416A1
(en)
|
2020-05-06 |
2021-11-11 |
Cellectis S.A. |
Methods to genetically modify cells for delivery of therapeutic proteins
|
|
US20230183664A1
(en)
|
2020-05-11 |
2023-06-15 |
Precision Biosciences, Inc. |
Self-limiting viral vectors encoding nucleases
|
|
KR20230022868A
(en)
|
2020-05-13 |
2023-02-16 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Method for producing donor-batch cells expressing a recombinant acceptor
|
|
US20240216508A1
(en)
|
2020-06-26 |
2024-07-04 |
Juno Therapeutics Gmbh |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
|
BR112023000327A2
(en)
|
2020-07-16 |
2023-01-31 |
Acuitas Therapeutics Inc |
CATION LIPIDS FOR USE IN LIPID NANOPARTICLES
|
|
EP4192875A1
(en)
|
2020-08-10 |
2023-06-14 |
Precision BioSciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
|
EP4501951A3
(en)
|
2020-08-25 |
2025-04-30 |
Kite Pharma, Inc. |
T cells with improved functionality
|
|
CA3196599A1
(en)
|
2020-09-25 |
2022-03-31 |
Sangamo Therapeutics, Inc. |
Zinc finger fusion proteins for nucleobase editing
|
|
IL301795A
(en)
|
2020-10-02 |
2023-05-01 |
Sangamo Therapeutics Inc |
Novel zinc finger protein transcription factors for repressing alpha-synuclein expression
|
|
US20230365995A1
(en)
|
2020-10-07 |
2023-11-16 |
Precision Biosciences, Inc. |
Lipid nanoparticle compositions
|
|
CR20230175A
(en)
|
2020-10-23 |
2023-07-26 |
Elo Life Systems Inc |
Methods for producing vanilla plants with improved flavor and agronomic production
|
|
EP4240756A1
(en)
|
2020-11-04 |
2023-09-13 |
Juno Therapeutics, Inc. |
Cells expressing a chimeric receptor from a modified invariant cd3 immunoglobulin superfamily chain locus and related polynucleotides and methods
|
|
MX2023005665A
(en)
|
2020-11-16 |
2023-08-01 |
Pig Improvement Co Uk Ltd |
Influenza a-resistant animals having edited anp32 genes.
|
|
EP4284823A1
(en)
|
2021-01-28 |
2023-12-06 |
Precision BioSciences, Inc. |
Modulation of tgf beta signaling in genetically-modified eukaryotic cells
|
|
WO2022226316A1
(en)
|
2021-04-22 |
2022-10-27 |
Precision Biosciences, Inc. |
Compositions and methods for generating male sterile plants
|
|
WO2023064872A1
(en)
|
2021-10-14 |
2023-04-20 |
Precision Biosciences, Inc. |
Combinations of anti-bcma car t cells and gamma secretase inhibitors
|
|
WO2023070003A1
(en)
|
2021-10-19 |
2023-04-27 |
Precision Biosciences, Inc. |
Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency
|
|
WO2023081900A1
(en)
|
2021-11-08 |
2023-05-11 |
Juno Therapeutics, Inc. |
Engineered t cells expressing a recombinant t cell receptor (tcr) and related systems and methods
|
|
US20250009800A1
(en)
|
2021-11-16 |
2025-01-09 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
|
US20250064032A1
(en)
|
2021-12-10 |
2025-02-27 |
Pig Improvement Company Uk Limited |
Editing tmprss2/4 for disease resistance in livestock
|
|
KR20240123832A
(en)
|
2021-12-16 |
2024-08-14 |
아퀴타스 테라퓨틱스 인크. |
Lipids for use in lipid nanoparticle formulations
|
|
CA3241193A1
(en)
|
2021-12-22 |
2023-06-29 |
Friedrich A. FAUSER |
Novel zinc finger fusion proteins for nucleobase editing
|
|
EP4460571A1
(en)
|
2022-01-05 |
2024-11-13 |
Vib Vzw |
Means and methods to increase abiotic stress tolerance in plants
|
|
WO2023131637A1
(en)
|
2022-01-06 |
2023-07-13 |
Vib Vzw |
Improved silage grasses
|
|
WO2023144199A1
(en)
|
2022-01-26 |
2023-08-03 |
Vib Vzw |
Plants having reduced levels of bitter taste metabolites
|
|
WO2024013514A2
(en)
|
2022-07-15 |
2024-01-18 |
Pig Improvement Company Uk Limited |
Gene edited livestock animals having coronavirus resistance
|
|
WO2024100604A1
(en)
|
2022-11-09 |
2024-05-16 |
Juno Therapeutics Gmbh |
Methods for manufacturing engineered immune cells
|
|
CN121002052A
(en)
|
2023-02-03 |
2025-11-21 |
C3S2 有限公司 |
Methods for non-viral production of engineered immune cells
|
|
CN121152635A
(en)
|
2023-03-31 |
2025-12-16 |
布里卡尔治疗公司 |
Methods for enhancing immunogenicity of cellular vaccines
|
|
WO2024216118A1
(en)
|
2023-04-14 |
2024-10-17 |
Precision Biosciences, Inc. |
Muscle-specific expression cassettes
|
|
WO2024216116A1
(en)
|
2023-04-14 |
2024-10-17 |
Precision Biosciences, Inc. |
Muscle-specific expression cassettes
|
|
WO2024238723A1
(en)
|
2023-05-16 |
2024-11-21 |
Omega Therapeutics, Inc. |
Methods and compositions for modulating pcsk9 expression
|
|
WO2024238726A1
(en)
|
2023-05-16 |
2024-11-21 |
Omega Therapeutics, Inc. |
Methods and compositions for modulating methylation of a target gene
|
|
TW202515898A
(en)
|
2023-06-30 |
2025-04-16 |
日商武田藥品工業股份有限公司 |
Htt repressors and uses thereof
|
|
WO2025019742A1
(en)
|
2023-07-19 |
2025-01-23 |
Omega Therapeutics, Inc. |
Methods and compositions for modulating ctnnb1 expression
|
|
WO2025194124A1
(en)
|
2024-03-14 |
2025-09-18 |
Tessera Therapeutics, Inc. |
Modified st1cas9 guide nucleic acids
|
|
WO2025235563A1
(en)
|
2024-05-07 |
2025-11-13 |
Omega Therapeutics, Inc. |
Epigenetic modulation for upregulation of genes
|
|
US20250345431A1
(en)
|
2024-05-10 |
2025-11-13 |
Juno Therapeutics, Inc. |
Genetically engineered t cells expressing a cd19 chimeric antigen receptor (car) and uses thereof for allogeneic cell therapy
|