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AU2002308000A1 - Antibacterial oxazolidinones with a cyclic sulphilimine or sulphoximine - Google Patents

Antibacterial oxazolidinones with a cyclic sulphilimine or sulphoximine

Info

Publication number
AU2002308000A1
AU2002308000A1 AU2002308000A AU2002308000A AU2002308000A1 AU 2002308000 A1 AU2002308000 A1 AU 2002308000A1 AU 2002308000 A AU2002308000 A AU 2002308000A AU 2002308000 A AU2002308000 A AU 2002308000A AU 2002308000 A1 AU2002308000 A1 AU 2002308000A1
Authority
AU
Australia
Prior art keywords
sulphilimine
sulphoximine
cyclic
oxazolidinones
antibacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002308000A
Inventor
Michael John Betts
Neil James Hales
Hoan Khai Huynh
Michael Lingard Swain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2002308000A1 publication Critical patent/AU2002308000A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU2002308000A 2001-04-07 2002-04-03 Antibacterial oxazolidinones with a cyclic sulphilimine or sulphoximine Abandoned AU2002308000A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0108764.2 2001-04-07
GBGB0108764.2A GB0108764D0 (en) 2001-04-07 2001-04-07 Chemical compounds
PCT/GB2002/001615 WO2002080841A2 (en) 2001-04-07 2002-04-03 Antibacterial oxazolidinones with a cyclic sulphilimine or sulphoximine

Publications (1)

Publication Number Publication Date
AU2002308000A1 true AU2002308000A1 (en) 2002-10-21

Family

ID=9912442

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002308000A Abandoned AU2002308000A1 (en) 2001-04-07 2002-04-03 Antibacterial oxazolidinones with a cyclic sulphilimine or sulphoximine

Country Status (3)

Country Link
AU (1) AU2002308000A1 (en)
GB (1) GB0108764D0 (en)
WO (1) WO2002080841A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
DK1427711T3 (en) 2001-09-11 2005-10-17 Astrazeneca Ab Oxazolidinone and / or isoxazoline derivatives as antibacterial agents
US7022705B2 (en) 2001-10-25 2006-04-04 Astrazeneca Ab Isoxazoline derivatives useful as antimicrobials
WO2003072575A1 (en) 2002-02-28 2003-09-04 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
NZ535591A (en) 2002-02-28 2006-07-28 Astrazeneca Ab Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
AR043050A1 (en) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc BIFunctional HETEROCICLICAL COMPOUNDS AND METHODS TO PREPARE AND USE THE SAME
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
PT1656370E (en) 2003-06-03 2012-11-29 Rib X Pharmaceuticals Inc Biaryl heterocyclic compounds and methods of making and using the same
US7265140B2 (en) * 2003-09-23 2007-09-04 Pfizer Inc Acyloxymethylcarbamate prodrugs of oxazolidinones
AR046782A1 (en) 2003-12-17 2005-12-21 Rib X Pharmaceuticals Inc HALEROCICLY COMPOUNDS OF HALOGENATED BIARILO, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, METHODS FOR THEIR ELABORATION AND ITS USE AS MEDICATIONS.
EP1723159B1 (en) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Macrocyclic compounds and methods of making and using the same
KR101394307B1 (en) 2005-06-08 2014-05-13 멜린타 테라퓨틱스, 인크. Process for the synthesis of triazoles
CN112543756A (en) 2018-07-25 2021-03-23 卡迪拉保健有限公司 Substituted oxazolidinones for the treatment of mammalian infections
WO2020234636A1 (en) 2019-05-17 2020-11-26 Cadila Healthcare Limited Novel compounds for the treatment of mammalian infections
WO2021184339A1 (en) * 2020-03-20 2021-09-23 Merck Sharp & Dohme Corp. Oxazolidinone compound and methods of use thereof as an antibacterial agent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
SK283487B6 (en) * 1995-09-01 2003-08-05 Pharmacia And Upjohn Company Phenyloxazolidinones having C-C bond in 4 to 8 membered heterocyclic rings
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
JP2003518117A (en) * 1999-12-21 2003-06-03 ファルマシア・アンド・アップジョン・カンパニー Oxazolidinones with sulfoximine functional groups and their use as antimicrobial agents

Also Published As

Publication number Publication date
WO2002080841A3 (en) 2003-02-27
GB0108764D0 (en) 2001-05-30
WO2002080841A2 (en) 2002-10-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase