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AU2002304785A1 - Use of cysteine protease-inhibitors for treating illnesses - Google Patents

Use of cysteine protease-inhibitors for treating illnesses

Info

Publication number
AU2002304785A1
AU2002304785A1 AU2002304785A AU2002304785A AU2002304785A1 AU 2002304785 A1 AU2002304785 A1 AU 2002304785A1 AU 2002304785 A AU2002304785 A AU 2002304785A AU 2002304785 A AU2002304785 A AU 2002304785A AU 2002304785 A1 AU2002304785 A1 AU 2002304785A1
Authority
AU
Australia
Prior art keywords
inhibitors
cysteine protease
treating illnesses
illnesses
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002304785A
Inventor
Wilfried Lubisch
Achim Moeller
Heinz Neuhof
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Abbott GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott GmbH and Co KG filed Critical Abbott GmbH and Co KG
Publication of AU2002304785A1 publication Critical patent/AU2002304785A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002304785A 2001-03-26 2002-03-26 Use of cysteine protease-inhibitors for treating illnesses Abandoned AU2002304785A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10114762.7 2001-03-26
DE10114762A DE10114762A1 (en) 2001-03-26 2001-03-26 Treatment of lung diseases, especially adult respiratory distress syndrome, by administration of cysteine protease inhibitor, especially calpain inhibitor
PCT/EP2002/003399 WO2003080182A1 (en) 2001-03-26 2002-03-26 Use of cysteine protease-inhibitors for treating illnesses

Publications (1)

Publication Number Publication Date
AU2002304785A1 true AU2002304785A1 (en) 2003-10-08

Family

ID=7679056

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002304785A Abandoned AU2002304785A1 (en) 2001-03-26 2002-03-26 Use of cysteine protease-inhibitors for treating illnesses

Country Status (3)

Country Link
AU (1) AU2002304785A1 (en)
DE (1) DE10114762A1 (en)
WO (1) WO2003080182A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101616908B (en) 2006-12-29 2014-09-10 Abbvie德国有限责任两合公司 Carboxamide compounds and their use as calpain inhibitors
TWI453019B (en) 2007-12-28 2014-09-21 Abbvie Deutschland Carboxamide compounds
WO2009145956A2 (en) * 2008-03-06 2009-12-03 The Trustees Of Columbia University In The City Of New York Uses of calpain inhibitors to inhibit inflammation
TWI519530B (en) 2009-02-20 2016-02-01 艾伯維德國有限及兩合公司 Carboxamide compounds and their use as calpain inhibitors
US8236798B2 (en) 2009-05-07 2012-08-07 Abbott Gmbh & Co. Kg Carboxamide compounds and their use as calpain inhibitors
US8598211B2 (en) 2009-12-22 2013-12-03 Abbvie Inc. Carboxamide compounds and their use as calpain inhibitors IV
US9051304B2 (en) 2009-12-22 2015-06-09 AbbVie Deutschland GmbH & Co. KG Carboxamide compounds and their use as calpain inhibitors V
EP2648731B1 (en) 2010-12-09 2017-01-25 Abbvie Deutschland GmbH & Co. KG Carboxamide compounds and their use as calpain inhibitors v
CA2867210A1 (en) 2012-04-03 2013-10-10 AbbVie Deutschland GmbH & Co. KG Carboxamide compounds and their use as calpain inhibitors v
EP3426674A4 (en) 2016-03-09 2019-08-14 Blade Therapeutics, Inc. CYCLIC CE-AMIDE COMPOUNDS AS MODULATORS OF CALPAIN, AND METHODS OF MAKING AND USING SAME
US11292801B2 (en) 2016-07-05 2022-04-05 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
AU2017336523B2 (en) 2016-09-28 2022-07-21 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013549A1 (en) * 1991-02-07 1992-08-20 Research Corporation Technologies, Inc. Inhibition of cell proliferation by hydrophobic peptides
US5916887A (en) * 1996-09-23 1999-06-29 National Research Council Of Canada 4-substituted-3-(2-amino-2-cycloalkyl methyl)-acetamido azetidin-2-one derivatives as cysteine proteinase regulators
DE19642591A1 (en) * 1996-10-15 1998-04-16 Basf Ag New piperidine-ketocarboxylic acid derivatives, their production and use
DE19648793A1 (en) * 1996-11-26 1998-05-28 Basf Ag New benzamides and their application
DE19818614A1 (en) * 1998-04-20 1999-10-21 Basf Ag New benzamide derivatives useful as cysteine protease inhibitors for treating neurodegenerative diseases, neuronal damage, stroke, cranial trauma, Alzheimer's disease, etc.
CA2328396C (en) * 1998-04-20 2009-02-10 Basf Aktiengesellschaft New substituted amides, their production and their use
DE19817461A1 (en) * 1998-04-20 1999-10-21 Basf Ag New benzamide derivatives useful as cysteine protease inhibitors for treating neurodegenerative diseases, neuronal damage, stroke, cranial trauma, Alzheimer's disease, etc.
ES2325140T3 (en) * 1998-04-20 2009-08-26 ABBOTT GMBH & CO. KG AMIDAS REPLACED WITH HETEROCICLES AS INHIBITORS OF THE CALPAINA.
DE19817459A1 (en) * 1998-04-20 1999-10-21 Basf Ag New heterocyclic amide derivatives useful as cysteine protease inhibitors for treating neurodegenerative diseases, neuronal damage, stroke, cranial trauma, Alzheimer's disease, etc.
BR9909819A (en) * 1998-04-20 2000-12-19 Basf Ag Amide, use of amides, and, pharmaceutical preparation for oral, parenteral or intraperitoneal use
WO1999061423A1 (en) * 1998-05-25 1999-12-02 Basf Aktiengesellschaft New heterocyclically substituted amides, their production and their use

Also Published As

Publication number Publication date
WO2003080182A1 (en) 2003-10-02
DE10114762A1 (en) 2002-10-02

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase