AU2002366362A1 - 2-substituted pyrrolo(2.1-a)isoquinolines against cancer - Google Patents

2-substituted pyrrolo(2.1-a)isoquinolines against cancer

Info

Publication number: AU2002366362A1
Authority: AU; Australia
Prior art keywords: isoquinolines; against cancer; substituted pyrrolo; pyrrolo; substituted
Prior art date: 2001-12-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2002366362A

Other languages

English (en)

Inventor

Stephen J. Boyer

Jennifer Burke

Nils Burkhardt

Christopher A. Carter

Dongping Fan

Tindy Li

Maria Niewoehner

Ulrich Niewoehner

Josef Pernerstorfer

Brian C. Raudenbush

Ming Wang

Yamin Wang

Wai C. Wong

Shihong Ying

Chengzhi Zhang

Qian Zhao

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer AG

Bayer Corp

Original Assignee

Bayer AG

Bayer Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-18

Filing date

2002-12-18

Publication date

2003-06-30

2002-12-18 Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG

2003-06-30 Publication of AU2002366362A1 publication Critical patent/AU2002366362A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AU2002366362A 2001-12-18 2002-12-18 2-substituted pyrrolo(2.1-a)isoquinolines against cancer Abandoned AU2002366362A1 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US34136701P	2001-12-18	2001-12-18
US60/341,367		2001-12-18
US34231001P	2001-12-19	2001-12-19
US60/342,310		2001-12-19
PCT/US2002/040328 WO2003051877A1 (fr)	2001-12-18	2002-12-18	2-substitues pyrrolo[2.1-a]isoquinolines contre le cancer

Publications (1)

Publication Number	Publication Date
AU2002366362A1 true AU2002366362A1 (en)	2003-06-30

Family

ID=26992477

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2002366362A Abandoned AU2002366362A1 (en)	2001-12-18	2002-12-18	2-substituted pyrrolo(2.1-a)isoquinolines against cancer

Country Status (2)

Country	Link
AU (1)	AU2002366362A1 (fr)
WO (1)	WO2003051877A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN113735681A (zh) *	2021-10-11	2021-12-03	丽珠集团新北江制药股份有限公司	一种氟雷拉纳中间体及其制备氟雷拉纳的方法

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA05013553A (es) *	2003-06-30	2006-03-09	Altana Pharma Ag	Pirrolodihidroisoquinolinas como inhibidores de pde10.
ATE438398T1 (de) *	2003-06-30	2009-08-15	Nycomed Gmbh	Pyrrolo-dihydroisochinolin-derivate als pde10- inhibitoren
WO2005028426A1 (fr) *	2003-09-19	2005-03-31	Chugai Seiyaku Kabushiki Kaisha	Nouveau derive de 4-phenylamino-benzaldoxime et son utilisation en tant qu'inhibiteur de mek
JP2007509044A (ja)	2003-10-08	2007-04-12	バーテックス　ファーマシューティカルズ　インコーポレイテッド	シクロアルキルピラニル基を含むａｔｐ結合カセットトランスポーターのモジュレータ
US7618981B2 (en) *	2004-05-06	2009-11-17	Cytokinetics, Inc.	Imidazopyridinyl-benzamide anti-cancer agents
MY144232A (en)	2004-07-26	2011-08-15	Chugai Pharmaceutical Co Ltd	5-substituted-2-phenylamino benzamides as mek inhibitors
EP1645556A1 (fr) *	2004-10-07	2006-04-12	Boehringer Ingelheim International GmbH	Derives d'arylpiperazine-benzoylamide utiles comme agents pharmaceutiques
JP2008526818A (ja) *	2005-01-12	2008-07-24	ニコメッドゲゼルシャフトミットベシュレンクテルハフツング	Ｐｄｅ１０インヒビターとしての新規のピロロジヒドロイソキノリン
ME01541B (me)	2005-04-13	2014-04-20	Astex Therapeutics Ltd	DERIVATI HIDROKSIBENZAMIDA l NJIHOVA PRIMJENA KAO INHIBITORA HSP90
US7754725B2 (en)	2006-03-01	2010-07-13	Astex Therapeutics Ltd.	Dihydroxyphenyl isoindolymethanones
US9730912B2 (en)	2006-10-12	2017-08-15	Astex Therapeutics Limited	Pharmaceutical compounds
WO2008044027A2 (fr)	2006-10-12	2008-04-17	Astex Therapeutics Limited	Composés pharmaceutiques
JP5528807B2 (ja)	2006-10-12	2014-06-25	アステックス、セラピューティックス、リミテッド	複合薬剤
EP2073802A1 (fr)	2006-10-12	2009-07-01	Astex Therapeutics Limited	Combinaisons pharmaceutiques
JP5528806B2 (ja)	2006-10-12	2014-06-25	アステックス、セラピューティックス、リミテッド	複合薬剤
GB0620259D0 (en)	2006-10-12	2006-11-22	Astex Therapeutics Ltd	Pharmaceutical compounds
TW200944523A (en)	2008-02-08	2009-11-01	Organon Nv	(Dihydro)pyrrolo[2,1-a]isoquinolines
GB0806527D0 (en)	2008-04-11	2008-05-14	Astex Therapeutics Ltd	Pharmaceutical compounds
WO2011008597A1 (fr) *	2009-07-14	2011-01-20	Schering Corporation	Dérivés de dihydroimidazoisoquinoléine utiles en tant qu'inhibiteurs de pde10
GB201021104D0 (en) *	2010-12-13	2011-01-26	Univ Leuven Kath	Novel compounds for the treatment of neurodegenerative diseases
US20120174381A1 (en)	2011-01-10	2012-07-12	David Messick	Apparatus and method for frame crimping
US10023564B2 (en)	2014-08-08	2018-07-17	The Regents Of The University Of Michigan	G protein-coupled receptor kinase 2 inhibitors and methods for use of the same
US11952378B1 (en)	2023-12-14	2024-04-09	King Faisal University	Pyrrolo[2,3-c]isoquinoline-1,2-dione compounds as CK2 inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002048144A1 (fr) *	2000-12-13	2002-06-20	Bayer Aktiengesellschaft	Pyrrolo (2.1-a) dihydroisoquinolines et utilisation en tant qu'inhibiteurs de phosphodiesterase 10a

2002
- 2002-12-18 AU AU2002366362A patent/AU2002366362A1/en not_active Abandoned
- 2002-12-18 WO PCT/US2002/040328 patent/WO2003051877A1/fr not_active Ceased

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN113735681A (zh) *	2021-10-11	2021-12-03	丽珠集团新北江制药股份有限公司	一种氟雷拉纳中间体及其制备氟雷拉纳的方法
CN113735681B (zh) *	2021-10-11	2023-12-12	丽珠集团新北江制药股份有限公司	一种氟雷拉纳中间体及其制备氟雷拉纳的方法

Also Published As

Publication number	Publication date
WO2003051877A1 (fr)	2003-06-26

Publication	Publication Date	Title
AU2002366362A1 (en)	2003-06-30	2-substituted pyrrolo(2.1-a)isoquinolines against cancer
AU2002359373A1 (en)	2003-06-23	Alkene-platinum-silyl complexes
AU2002210714A1 (en)	2002-06-11	Substituted quinolines as antitumor agents
AU2002247304A1 (en)	2002-09-19	Anti-neovasculature preparations for cancer
AU2002360766A1 (en)	2003-07-30	Methods for cancer imaging
AU2002224595A1 (en)	2002-02-13	Antitumor agents
AU2002253971A1 (en)	2002-09-12	Rotatable shelf
AUPR969501A0 (en)	2002-01-24	Forfaiting transactions
AU2002343312A1 (en)	2003-06-10	Two fixed-beams tx-diversity
AU2002357476A1 (en)	2003-06-10	Metal detector
AU2002356405A1 (en)	2003-06-10	Locking amplifier
AU7446000A (en)	2001-04-30	Antitumor agents
AU2002351382A1 (en)	2003-06-23	Combination cancer therapy
AU2002330997A1 (en)	2003-02-24	Pyrrolo(2.1-a)isoquinoline derivatives
AU2002355846A1 (en)	2003-02-17	Immune complexes
AU2002355340A1 (en)	2003-02-24	3-substituted pyrrolo (2.1-a) isoquinoline derivatives
AU2002326524A1 (en)	2003-02-24	3-substituted pyrrolo(2.1-a)isoquinoline derivatives
AU2002335452A1 (en)	2003-04-14	Antitumor agent
AU2002310928A1 (en)	2002-10-21	Palladium-complexes based on pyrroline-metal complexes
AU2002313260A1 (en)	2003-01-08	Antitumor agents
AU2002309041A1 (en)	2002-11-25	Antitumor agents
AU2002336502A1 (en)	2003-04-01	New antitumor agent
AU2002355220A1 (en)	2003-02-17	Cancer diagnostics
AUPR639601A0 (en)	2001-08-09	Quinoxaline derivatives
AU2002243125A1 (en)	2002-09-04	Anticancer agent

Legal Events

Date	Code	Title	Description
2004-09-16	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase