AU2002360305A1 - Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample - Google Patents
Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sampleInfo
- Publication number
- AU2002360305A1 AU2002360305A1 AU2002360305A AU2002360305A AU2002360305A1 AU 2002360305 A1 AU2002360305 A1 AU 2002360305A1 AU 2002360305 A AU2002360305 A AU 2002360305A AU 2002360305 A AU2002360305 A AU 2002360305A AU 2002360305 A1 AU2002360305 A1 AU 2002360305A1
- Authority
- AU
- Australia
- Prior art keywords
- nucleic acids
- same sample
- morphological features
- multiparameter analysis
- comprehensive nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000000877 morphologic effect Effects 0.000 title 1
- 238000011527 multiparameter analysis Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2550/00—Electrophoretic profiling, e.g. for proteome analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33066901P | 2001-10-26 | 2001-10-26 | |
| US60/330,669 | 2001-10-26 | ||
| US36994502P | 2002-04-04 | 2002-04-04 | |
| US60/369,945 | 2002-04-04 | ||
| PCT/US2002/034397 WO2003035894A2 (fr) | 2001-10-26 | 2002-10-28 | Analyse de parametres multiples d'acides nucleiques et de caracteristiques morphologiques d'ensemble sur le meme echantillon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002360305A1 true AU2002360305A1 (en) | 2003-05-06 |
Family
ID=26987390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002360305A Abandoned AU2002360305A1 (en) | 2001-10-26 | 2002-10-28 | Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1438398A2 (fr) |
| JP (1) | JP2005507997A (fr) |
| KR (1) | KR20040047971A (fr) |
| CN (1) | CN1610752A (fr) |
| AU (1) | AU2002360305A1 (fr) |
| BR (1) | BR0213520A (fr) |
| CA (2) | CA2465274A1 (fr) |
| IL (1) | IL161357A0 (fr) |
| WO (2) | WO2003035894A2 (fr) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6913697B2 (en) | 2001-02-14 | 2005-07-05 | Science & Technology Corporation @ Unm | Nanostructured separation and analysis devices for biological membranes |
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| US7318902B2 (en) | 2002-02-04 | 2008-01-15 | Colorado School Of Mines | Laminar flow-based separations of colloidal and cellular particles |
| AU2003277153A1 (en) | 2002-09-27 | 2004-04-19 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| WO2005040396A2 (fr) * | 2003-10-16 | 2005-05-06 | Genomic Health, Inc. | Systeme d'essai qrt-pcr pour le profilage d'expression genetique |
| US7332597B2 (en) | 2004-06-28 | 2008-02-19 | University Of Kentucky Research Foundation | Primers and probe to identify mycobacterium tuberculosis complex |
| ITBO20040420A1 (it) | 2004-07-07 | 2004-10-07 | Type S R L | Macchina per taglio e formatura di piattine metalliche |
| DE102005013261A1 (de) * | 2005-03-22 | 2006-09-28 | Adnagen Ag | Reagenz und Verfahren zur Verhinderung der zeitabhängigen Expression in biologischen Zellen |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| DE102005029808A1 (de) * | 2005-06-27 | 2007-01-04 | Siemens Ag | Trägermaterial, Verfahren zu seiner Herstellung und Verwendung |
| ITBO20050481A1 (it) | 2005-07-19 | 2007-01-20 | Silicon Biosystems S R L | Metodo ed apparato per la manipolazione e/o l'individuazione di particelle |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| KR101446626B1 (ko) | 2005-09-02 | 2014-10-06 | 도레이 카부시키가이샤 | 신장암 진단, 신장암 환자 예후 예측을 위한 조성물 및 방법 |
| US20070059683A1 (en) * | 2005-09-15 | 2007-03-15 | Tom Barber | Veterinary diagnostic system |
| US9134237B2 (en) | 2005-09-20 | 2015-09-15 | Janssen Diagnotics, LLC | High sensitivity multiparameter method for rare event analysis in a biological sample |
| ES2886923T3 (es) | 2005-09-20 | 2021-12-21 | Menarini Silicon Biosystems Spa | Métodos y composición para generar sondas de ADN de secuencia única, marcaje de sondas de ADN y el uso de estas sondas |
| ITBO20050646A1 (it) | 2005-10-26 | 2007-04-27 | Silicon Biosystem S R L | Metodo ed apparato per la caratterizzazione ed il conteggio di particelle |
| US8119976B2 (en) | 2007-07-03 | 2012-02-21 | Colorado School Of Mines | Optical-based cell deformability |
| US9885644B2 (en) | 2006-01-10 | 2018-02-06 | Colorado School Of Mines | Dynamic viscoelasticity as a rapid single-cell biomarker |
| US9487812B2 (en) | 2012-02-17 | 2016-11-08 | Colorado School Of Mines | Optical alignment deformation spectroscopy |
| US9878326B2 (en) | 2007-09-26 | 2018-01-30 | Colorado School Of Mines | Fiber-focused diode-bar optical trapping for microfluidic manipulation |
| ITTO20060226A1 (it) | 2006-03-27 | 2007-09-28 | Silicon Biosystem S P A | Metodo ed apparato per il processamento e o l'analisi e o la selezione di particelle, in particolare particelle biologiche |
| US8012480B2 (en) * | 2006-04-18 | 2011-09-06 | Wellstat Biologics Corporation | Detection of proteins from circulating neoplastic cells |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| EP2589668A1 (fr) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Analyse de cellules rares utilisant la division d'échantillons et les marqueurs d'ADN |
| WO2007147074A2 (fr) | 2006-06-14 | 2007-12-21 | Living Microsystems, Inc. | Utilisation de génotypage snp fortement parallèle pour diagnostic fœtal |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| CA2657621A1 (fr) | 2006-07-14 | 2008-01-17 | Aviva Biosciences Corporation | Procedes et compositions servant a detecter des cellules rares dans un echantillon biologique |
| JP4926812B2 (ja) * | 2007-02-01 | 2012-05-09 | シスメックス株式会社 | 血球分析装置および体液分析方法 |
| US10722250B2 (en) | 2007-09-04 | 2020-07-28 | Colorado School Of Mines | Magnetic-field driven colloidal microbots, methods for forming and using the same |
| ITTO20070771A1 (it) | 2007-10-29 | 2009-04-30 | Silicon Biosystems Spa | Metodo e apparato per la identificazione e manipolazione di particelle |
| WO2010033578A2 (fr) | 2008-09-20 | 2010-03-25 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic non effractif d'aneuploïdie foetale par sequençage |
| IT1391619B1 (it) | 2008-11-04 | 2012-01-11 | Silicon Biosystems Spa | Metodo per l'individuazione, selezione e analisi di cellule tumorali |
| US10895575B2 (en) | 2008-11-04 | 2021-01-19 | Menarini Silicon Biosystems S.P.A. | Method for identification, selection and analysis of tumour cells |
| CA2782123C (fr) | 2009-03-17 | 2017-05-02 | Silicon Biosystems S.P.A. | Dispositif microfluidique |
| JP5729904B2 (ja) * | 2009-06-02 | 2015-06-03 | キヤノン株式会社 | 細胞から蛋白質、dna、rnaを調製する方法 |
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| EP2614160B1 (fr) | 2010-09-10 | 2016-04-06 | Bio-Rad Laboratories, Inc. | Détection des régions d'interaction de l'arn au sein de l'adn |
| CN102565404B (zh) * | 2010-12-24 | 2014-04-16 | 牛刚 | 一种检测血液中游离大肠癌细胞标志物的试剂盒 |
| CN102156164B (zh) * | 2011-01-13 | 2012-12-12 | 北京肿瘤医院 | 核仁磷酸蛋白可变剪接体的质谱鉴定方法和胃癌诊断试剂盒 |
| CN102109525B (zh) * | 2011-01-26 | 2013-10-16 | 牛刚 | 一种检测血液中游离乳腺癌细胞标志物的试剂盒 |
| WO2012112606A1 (fr) | 2011-02-15 | 2012-08-23 | Bio-Rad Laboratories, Inc. | Détection de méthylation dans une sous-population d'adn génomique |
| US20120252038A1 (en) * | 2011-04-01 | 2012-10-04 | Chianese David A | Steroid receptor assays |
| WO2013019960A1 (fr) | 2011-08-03 | 2013-02-07 | Bio-Rad Laboratories, Inc. | Filtration de petits acides nucléiques à l'aide de cellules perméabilisées |
| ITTO20110990A1 (it) | 2011-10-28 | 2013-04-29 | Silicon Biosystems Spa | Metodo ed apparato per l'analisi ottica di particelle a basse temperature |
| ITBO20110766A1 (it) | 2011-12-28 | 2013-06-29 | Silicon Biosystems Spa | Dispositivi, apparato, kit e metodo per il trattamento di un campione biologico |
| WO2014067528A1 (fr) * | 2012-10-29 | 2014-05-08 | Arcedi Biotech Aps | Enrichissement et détection améliorés de cellules sanguines rares |
| EP2972202B1 (fr) * | 2013-03-15 | 2017-11-15 | Iris International, Inc. | Procédé et composition permettant de colorer et de traiter un échantillon d'urine |
| US9857361B2 (en) | 2013-03-15 | 2018-01-02 | Iris International, Inc. | Flowcell, sheath fluid, and autofocus systems and methods for particle analysis in urine samples |
| US9771571B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| CN111484992B (zh) * | 2014-02-28 | 2024-04-02 | 简·探针公司 | 从含有甲醛的液基细胞学防腐剂中的样本分离核酸的方法 |
| US9771572B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| JP2014158468A (ja) * | 2014-03-05 | 2014-09-04 | Clinical Genomics Pty Ltd | 検出方法 |
| RU2761432C2 (ru) * | 2015-02-10 | 2021-12-08 | Иллюмина, Инк. | Способ и композиция для анализа клеточных компонентов |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| US10282588B2 (en) * | 2016-06-09 | 2019-05-07 | Siemens Healthcare Gmbh | Image-based tumor phenotyping with machine learning from synthetic data |
| HUE068517T2 (hu) | 2017-10-19 | 2024-12-28 | Streck Llc | A hemolízis és a véralvadás szabályozására, valamint az extracelluláris vezikulák stabilizálására szolgáló készítmények |
| CN110456034B (zh) * | 2018-05-07 | 2022-07-22 | 上海市第十人民医院 | 一种循环肿瘤细胞的检测方法 |
| CN109402240B (zh) * | 2019-01-08 | 2020-08-25 | 圣湘生物科技股份有限公司 | 核酸释放剂、核酸pcr扩增方法和pcr扩增试剂盒 |
| WO2023080601A1 (fr) * | 2021-11-05 | 2023-05-11 | 고려대학교 세종산학협력단 | Procédé et dispositif de diagnostic de maladie faisant appel à une technologie d'imagerie par ombre sans lentille basée sur l'apprentissage machine |
| KR102707636B1 (ko) * | 2021-11-05 | 2024-09-20 | 고려대학교 세종산학협력단 | 머신러닝 기반의 렌즈프리 그림자 이미징 기술을 이용한 백혈병 진단 방법 및 장치 |
| JP7757800B2 (ja) * | 2022-01-14 | 2025-10-22 | 株式会社島津製作所 | 電気泳動システム、電気泳動装置、電気泳動解析方法、および、電気泳動解析プログラム |
| CN116042772B (zh) * | 2023-02-10 | 2025-07-29 | 上海立闻生物科技有限公司 | 针对少量来自于新鲜样本的肿瘤细胞全转录组测序的方法和试剂盒 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4929556A (en) * | 1986-02-06 | 1990-05-29 | The Dow Chemical Company | Enzyme immobilization with polysulfonium salts |
| US5346994A (en) * | 1992-01-28 | 1994-09-13 | Piotr Chomczynski | Shelf-stable product and process for isolating RNA, DNA and proteins |
| CA2262403C (fr) * | 1995-07-31 | 2011-09-20 | Urocor, Inc. | Biomarqueurs et cibles de diagnostic, de pronostic et de traitement du cancer de la prostate |
| PT938320E (pt) * | 1996-03-26 | 2010-09-22 | Michael S Kopreski | Método que permite a utilização de arn extracelular extraído de plasma ou de soro para detectar, monitorizar ou avaliar o cancro |
| US6156564A (en) * | 1996-06-07 | 2000-12-05 | The United States Of America As Represented By The Department Of Health And Human Services | Cellular apoptosis susceptibility protein (CSP) and antisense CSP |
| BR9907852A (pt) * | 1998-02-12 | 2000-10-24 | Immunivest Corp | Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes |
| US6156515A (en) * | 1999-02-09 | 2000-12-05 | Urocor, Inc. | Prostate-specific gene for diagnosis, prognosis and management of prostate cancer |
| US6358697B2 (en) * | 1999-04-21 | 2002-03-19 | Children's Hospital Medical Center | Intracellular pharmaceutical targeting |
-
2002
- 2002-10-28 CA CA002465274A patent/CA2465274A1/fr not_active Abandoned
- 2002-10-28 BR BRPI0213520-5A patent/BR0213520A/pt unknown
- 2002-10-28 WO PCT/US2002/034397 patent/WO2003035894A2/fr not_active Ceased
- 2002-10-28 CN CNA028261313A patent/CN1610752A/zh active Pending
- 2002-10-28 IL IL16135702A patent/IL161357A0/xx unknown
- 2002-10-28 AU AU2002360305A patent/AU2002360305A1/en not_active Abandoned
- 2002-10-28 KR KR10-2004-7006181A patent/KR20040047971A/ko not_active Withdrawn
- 2002-10-28 WO PCT/US2002/034570 patent/WO2003035895A2/fr not_active Ceased
- 2002-10-28 EP EP02795554A patent/EP1438398A2/fr not_active Withdrawn
- 2002-10-28 JP JP2003538395A patent/JP2005507997A/ja not_active Ceased
- 2002-10-28 CA CA002465288A patent/CA2465288A1/fr not_active Abandoned
- 2002-10-28 EP EP02795565A patent/EP1438419A2/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003035894A8 (fr) | 2004-06-03 |
| JP2005507997A (ja) | 2005-03-24 |
| CA2465288A1 (fr) | 2003-05-01 |
| WO2003035895A3 (fr) | 2004-01-08 |
| EP1438398A2 (fr) | 2004-07-21 |
| BR0213520A (pt) | 2006-05-23 |
| CN1610752A (zh) | 2005-04-27 |
| WO2003035895A2 (fr) | 2003-05-01 |
| IL161357A0 (en) | 2004-09-27 |
| WO2003035894A3 (fr) | 2003-12-04 |
| EP1438419A2 (fr) | 2004-07-21 |
| WO2003035894A2 (fr) | 2003-05-01 |
| CA2465274A1 (fr) | 2003-05-01 |
| KR20040047971A (ko) | 2004-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |