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AU2002348942A8 - Process for the preparation of tofisopam and new intermediates - Google Patents

Process for the preparation of tofisopam and new intermediates

Info

Publication number
AU2002348942A8
AU2002348942A8 AU2002348942A AU2002348942A AU2002348942A8 AU 2002348942 A8 AU2002348942 A8 AU 2002348942A8 AU 2002348942 A AU2002348942 A AU 2002348942A AU 2002348942 A AU2002348942 A AU 2002348942A AU 2002348942 A8 AU2002348942 A8 AU 2002348942A8
Authority
AU
Australia
Prior art keywords
tofisopam
preparation
new intermediates
intermediates
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002348942A
Other versions
AU2002348942A1 (en
Inventor
Pal Vago
Erika Molnarne Samu
Gyula Simig
Zoltan Greff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU0105326A external-priority patent/HU225411B1/en
Priority claimed from HU0105327A external-priority patent/HUP0105327A3/en
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of AU2002348942A8 publication Critical patent/AU2002348942A8/en
Publication of AU2002348942A1 publication Critical patent/AU2002348942A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22Radicals substituted by singly bound oxygen or sulfur atoms etherified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002348942A 2001-12-13 2002-12-12 Process for the preparation of tofisopam and new intermediates Abandoned AU2002348942A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
HUP0105327 2001-12-13
HU0105326A HU225411B1 (en) 2001-12-13 2001-12-13 Process for producing tofisopam
HU0105327A HUP0105327A3 (en) 2001-12-13 2001-12-13 Process for the production of 3-[2-(3,4-dimethoxybenzoyl)-4,5-dimethoxyphenyl]-pentane-2-one
HUP0105326 2001-12-13
PCT/HU2002/000141 WO2003050092A2 (en) 2001-12-13 2002-12-12 Process for the preparation of tofisopam and new intermediates

Publications (2)

Publication Number Publication Date
AU2002348942A8 true AU2002348942A8 (en) 2003-06-23
AU2002348942A1 AU2002348942A1 (en) 2003-06-23

Family

ID=89979996

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002348942A Abandoned AU2002348942A1 (en) 2001-12-13 2002-12-12 Process for the preparation of tofisopam and new intermediates

Country Status (7)

Country Link
EP (1) EP1465879A2 (en)
AU (1) AU2002348942A1 (en)
BG (1) BG108801A (en)
CZ (1) CZ2004792A3 (en)
PL (1) PL370036A1 (en)
SK (1) SK2792004A3 (en)
WO (1) WO2003050092A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227044B1 (en) * 2002-12-16 2010-05-28 Egis Gyogyszergyar Nyilvanosan Process for producing 3-[2-(3,4-dimethoxybenzoyl)-4,5-dimethoxyphenyl]-pentan-2-one
FR2996845A1 (en) * 2012-10-12 2014-04-18 Servier Lab NOVEL PROCESS FOR THE SYNTHESIS OF 3- (2-BROMO-4,5-DIMETHOXYPHENYL) PROPANENITRILE, AND APPLICATION TO THE SYNTHESIS OF IVABRADINE AND ITS SALTS OF ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA712798B (en) * 1970-11-06 1972-02-23 Egyt Gyogyszervegyeszeti Gyar New,pharmaceutically active 2,3-diazabicyclo(5.4.0)undecapentaene derivative and process for preparing same

Also Published As

Publication number Publication date
SK2792004A3 (en) 2004-11-03
CZ2004792A3 (en) 2004-12-15
PL370036A1 (en) 2005-05-16
AU2002348942A1 (en) 2003-06-23
BG108801A (en) 2005-04-30
EP1465879A2 (en) 2004-10-13
WO2003050092A2 (en) 2003-06-19
WO2003050092A3 (en) 2003-11-06

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase