AU2002348942A8 - Process for the preparation of tofisopam and new intermediates - Google Patents
Process for the preparation of tofisopam and new intermediatesInfo
- Publication number
- AU2002348942A8 AU2002348942A8 AU2002348942A AU2002348942A AU2002348942A8 AU 2002348942 A8 AU2002348942 A8 AU 2002348942A8 AU 2002348942 A AU2002348942 A AU 2002348942A AU 2002348942 A AU2002348942 A AU 2002348942A AU 2002348942 A8 AU2002348942 A8 AU 2002348942A8
- Authority
- AU
- Australia
- Prior art keywords
- tofisopam
- preparation
- new intermediates
- intermediates
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- RUJBDQSFYCKFAA-UHFFFAOYSA-N Tofisopam Chemical compound N=1N=C(C)C(CC)C2=CC(OC)=C(OC)C=C2C=1C1=CC=C(OC)C(OC)=C1 RUJBDQSFYCKFAA-UHFFFAOYSA-N 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 229960002501 tofisopam Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUP0105327 | 2001-12-13 | ||
| HU0105326A HU225411B1 (en) | 2001-12-13 | 2001-12-13 | Process for producing tofisopam |
| HU0105327A HUP0105327A3 (en) | 2001-12-13 | 2001-12-13 | Process for the production of 3-[2-(3,4-dimethoxybenzoyl)-4,5-dimethoxyphenyl]-pentane-2-one |
| HUP0105326 | 2001-12-13 | ||
| PCT/HU2002/000141 WO2003050092A2 (en) | 2001-12-13 | 2002-12-12 | Process for the preparation of tofisopam and new intermediates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002348942A8 true AU2002348942A8 (en) | 2003-06-23 |
| AU2002348942A1 AU2002348942A1 (en) | 2003-06-23 |
Family
ID=89979996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002348942A Abandoned AU2002348942A1 (en) | 2001-12-13 | 2002-12-12 | Process for the preparation of tofisopam and new intermediates |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1465879A2 (en) |
| AU (1) | AU2002348942A1 (en) |
| BG (1) | BG108801A (en) |
| CZ (1) | CZ2004792A3 (en) |
| PL (1) | PL370036A1 (en) |
| SK (1) | SK2792004A3 (en) |
| WO (1) | WO2003050092A2 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU227044B1 (en) * | 2002-12-16 | 2010-05-28 | Egis Gyogyszergyar Nyilvanosan | Process for producing 3-[2-(3,4-dimethoxybenzoyl)-4,5-dimethoxyphenyl]-pentan-2-one |
| FR2996845A1 (en) * | 2012-10-12 | 2014-04-18 | Servier Lab | NOVEL PROCESS FOR THE SYNTHESIS OF 3- (2-BROMO-4,5-DIMETHOXYPHENYL) PROPANENITRILE, AND APPLICATION TO THE SYNTHESIS OF IVABRADINE AND ITS SALTS OF ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA712798B (en) * | 1970-11-06 | 1972-02-23 | Egyt Gyogyszervegyeszeti Gyar | New,pharmaceutically active 2,3-diazabicyclo(5.4.0)undecapentaene derivative and process for preparing same |
-
2002
- 2002-12-12 PL PL02370036A patent/PL370036A1/en unknown
- 2002-12-12 CZ CZ2004792A patent/CZ2004792A3/en unknown
- 2002-12-12 WO PCT/HU2002/000141 patent/WO2003050092A2/en not_active Ceased
- 2002-12-12 EP EP02781451A patent/EP1465879A2/en not_active Withdrawn
- 2002-12-12 SK SK279-2004A patent/SK2792004A3/en unknown
- 2002-12-12 AU AU2002348942A patent/AU2002348942A1/en not_active Abandoned
-
2004
- 2004-07-13 BG BG108801A patent/BG108801A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK2792004A3 (en) | 2004-11-03 |
| CZ2004792A3 (en) | 2004-12-15 |
| PL370036A1 (en) | 2005-05-16 |
| AU2002348942A1 (en) | 2003-06-23 |
| BG108801A (en) | 2005-04-30 |
| EP1465879A2 (en) | 2004-10-13 |
| WO2003050092A2 (en) | 2003-06-19 |
| WO2003050092A3 (en) | 2003-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |